Protein

MIA_05557_1

Length
754 amino acids

Browser: contig08:805925-808378+

Protein function

EGGNOG:0PHACPGUG_02378DNA- helicase
SGD closest match:S000003628SRS2ATP-dependent DNA helicase SRS2
CGD closest match:CAL0000191874orf19.5970DNA helicase

Protein alignments

%idAln lengthE-value
MCA_02052_135.615%7165.16e-139MCA_02052_1
A0A0J9X763_GEOCN38.543%6594.06e-138Similar to Saccharomyces cerevisiae YJL092W SRS2 DNA helicase and DNA-dependent ATPase involved in DNA repair OS=Geotrichum candidum GN=BN980_GECA04s02947g PE=4 SV=1
UniRef50_A0A0J9X76338.543%6598.32e-135Similar to Saccharomyces cerevisiae YJL092W SRS2 DNA helicase and DNA-dependent ATPase involved in DNA repair n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X763_GEOCN
A0A060TCZ7_BLAAD31.982%6668.81e-91ARAD1B19910p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19910g PE=4 SV=1
A0A167BZ03_9ASCO31.164%5841.26e-64DNA helicase SRS2 OS=Sugiyamaella lignohabitans GN=SRS2 PE=4 SV=1
Q6C4F2_YARLI30.339%6795.02e-60YALI0E27269p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27269g PE=4 SV=1
A0A1E3PIX6_9ASCO27.697%6861.39e-51p-loop containing nucleoside triphosphate hydrolase protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_10623 PE=4 SV=1
Q5AND3_CANAL25.784%7334.81e-48DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5970 PE=4 SV=1
SRS2_YEAST29.002%4317.13e-29ATP-dependent DNA helicase SRS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRS2 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0107

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 754

Detailed signature matches

  1. Domain IPR014016
    UvrD-like helicase, ATP-binding domain
    1. PS51198 (UVRD_HELIC...)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR034739
    UvrD/AddA helicase, N-terminal
    1. PF00580 (UvrD-helicase)
  4. Domain IPR014017
    UvrD-like DNA helicase, C-terminal
    1. PF13361 (UvrD_C)
    2. PS51217 (UVRD_HELIC...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MIA_05557_1
MTDEEIEIGHEENVQQEMLDVSVVMNQEQYEAVTKPLGTNVQVLAGPGTGKTLTLVNRVLYLLSKGVPPNSILVLTYTNR
AIYEFRTRLNGVLGQELGSRLRIHTVHSYCQDLLMRHGQLIGLPEVQIIANKLDKEYIEGIVIRKIQNMHACKDYKEAKR
LFHAALDSKLNKRSLSPVLESLKKDVLEIYNEELHKAFLFDYDDLIILTEKLLIKFPEVAKDLDSVLVDEFQDISQPLWN
VIKRLAIHSSLYVAGDPDQNIFGFLGAHSLIFKEMRNAFKVDQVILTRSYRSSQPILDAAYELISHDKQREHSKKLVADE
SYLSQNMIENTPPRLIVLKTATDEMDWVSCTARLLMDQGVPANDIVVLARTGRIASEIADPIQHGSGARTIVIGGTSLLE
TEEASVCNTILRFLQYPNRNLFVLNLIRRYRLFITPKDLDMAISKAAEEGVSLIDVFRDPSPWITSAKREKLNSFLEMID
RSHDIMRENPQSLENVIEALRYCLGKLQLAEKVRLKYTRTYRKRMRNIDKFIEYLYSIKDYVAWELESHPERTFLEQLLA
SSVFYHITPTVDELVISTVHAAKGREWRVVFIVNADDKVYPHMRTHGSPKELNEERRVLYVAMTRAKERLLISYHKESPY
NTFTENTPSRFFTKPVLNKFEVTKGTVDPSSVYSNCKFLSFTITYFLLTFYPKDALAEAKYPLLFKQPQYYSTTVKKRFH
TLARPTAPTHGSIYALSITARRFSHIPRLMSRFL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.