Protein

MCA_02052_1

Length
742 amino acids

Description: UvrD-like helicase

Browser: contigB:104742-107219-

RNA-seq: read pairs 851, FPKM 14.2, percentile rank 32.7% (100% = highest expression)

Protein function

Annotation:UvrD-like helicase
KEGG:K03657uvrD DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]
EGGNOG:0PHACPGUG_02378DNA- helicase
SGD closest match:S000003628SRS2ATP-dependent DNA helicase SRS2
CGD closest match:CAL0000191874orf19.5970DNA helicase

Protein alignments

%idAln lengthE-value
MIA_05557_135.61%7162e-137MIA_05557_1
A0A0J9X763_GEOCN30.20%7122e-98Similar to Saccharomyces cerevisiae YJL092W SRS2 DNA helicase and DNA-dependent ATPase involved in DNA repair OS=Geotrichum candidum GN=BN980_GECA04s02947g PE=4 SV=1
UniRef50_A0A0J9X76330.20%7125e-95Similar to Saccharomyces cerevisiae YJL092W SRS2 DNA helicase and DNA-dependent ATPase involved in DNA repair n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X763_GEOCN
A0A060TCZ7_BLAAD27.51%6981e-70ARAD1B19910p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19910g PE=4 SV=1
A0A1E3PIX6_9ASCO27.40%6973e-57p-loop containing nucleoside triphosphate hydrolase protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_10623 PE=4 SV=1
A0A167BZ03_9ASCO29.20%5894e-56DNA helicase SRS2 OS=Sugiyamaella lignohabitans GN=SRS2 PE=4 SV=1
Q6C4F2_YARLI26.10%7053e-51YALI0E27269p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E27269g PE=4 SV=1
Q5AND3_CANAL27.16%7401e-45DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.5970 PE=4 SV=1
SRS2_YEAST26.55%5317e-28ATP-dependent DNA helicase SRS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SRS2 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0125

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 742

Detailed signature matches

  1. Domain IPR014016
    UvrD-like helicase, ATP-binding domain
    1. PS51198 (UVRD_HELIC...)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR034739
    UvrD/AddA helicase, N-terminal
    1. PF00580 (UvrD-helicase)
  4. Domain IPR014017
    UvrD-like DNA helicase, C-terminal
    1. PF13361 (UvrD_C)
    2. PS51217 (UVRD_HELIC...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MCA_02052_1
MEDFEPEVYEIHPKVVVNKEQYEAITQPTSQNVQVIAGPGTGKTKTIINRVLYLISKGIVPSKIVVITLTNRATNELRAR
FEQLVGEDITNQLQISTIHGFCFTYLSRYGENIGVPKPIIIASNEDKNSIRNSIYNDFIQGKIDLELKDKDRKSFSSLFN
TAIDSNSLELASPILVQLKNLYKERLHSNGLLDYQDLITKGEELFKENEELSKYFEAIIIDEFQDLSLQLWNVVRNISKK
SALFVAGDPDQSIFLFRDEDRMTSLFDTMSLEFPDVKRLVFTRNYRSTQKILDLCYDVIDEDTKRLHSERLQRSRTDLVS
NLPSVEPCYYYFETISEEIKWVAFKISQLVVKENIPISEIAIISRTGNYPPEVISTLEELLPFKVILVGGNTGMRTEEGA
LCTSIIRLLLYPEQDSFTLNLIRKYKKFISPSKLNEAISTSQETGEPLLKVFEFPQFDKKSIQVKQFAQMVNNLRKKLLD
EALDGSSLISILKEFLNFIEYEKYLKSYYRATYKRRLHKMETVFEFISDISKKYEKPKTDTTFEGPDFLLSLLNAPLLSD
ITANNGLVVTTVHSAKGLEWKVVFLIDASDNSFPHVRSRGTEVAIAEERRILYVGLSRARDQLYITHSKEVPIYMDGFEF
QPSRFFNQKILDKIYKNGRIAGYSKPLSLADTKYNAVKSKYPLIFKPPPVLNRYEPSKLGQTRKYSTITGYYNPVMTRNI
VSMSKTSRNLFWLTRNVFSKIK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005524 ATP binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.