Protein

MIA_05556_1

Length
227 amino acids


Browser: contig08:805007-805789+

Protein function

EGGNOG:0PGK8FG00564.1The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)
SGD closest match:S000005889PRE10Probable proteasome subunit alpha type-7
CGD closest match:CAL0000177938PRE10Proteasome endopeptidase complex

Protein alignments

%idAln lengthE-value
MCA_02053_185.581%2151.59e-130MCA_02053_1
A0A0J9XC06_GEOCN82.326%2157.82e-128Proteasome endopeptidase complex OS=Geotrichum candidum GN=BN980_GECA09s03585g PE=3 SV=1
A0A1E3PN21_9ASCO76.056%2134.17e-118Proteasome endopeptidase complex OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82538 PE=3 SV=1
A0A060TC35_BLAAD78.404%2131.65e-117Proteasome endopeptidase complex OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B19888g PE=3 SV=1
Q6C2J2_YARLI68.396%2121.03e-105Proteasome endopeptidase complex OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F07469g PE=3 SV=1
A0A1D8PQW1_CANAL64.789%2135.12e-102Proteasome endopeptidase complex OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRE10 PE=3 SV=1
PSA7_YEAST65.278%2163.93e-96Probable proteasome subunit alpha type-7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PRE10 PE=1 SV=2
UniRef50_P2124265.278%2169.39e-93Probable proteasome subunit alpha type-7 n=42 Tax=saccharomyceta TaxID=716545 RepID=PSA7_YEAST
A0A1E4TFJ1_9ASCO58.962%2124.36e-87Proteasome endopeptidase complex OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31463 PE=3 SV=1
A0A167F7Z8_9ASCO80.645%933.01e-43Proteasome core particle subunit alpha 7 OS=Sugiyamaella lignohabitans GN=PRE10 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0197

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 227

Detailed signature matches

    1. PF00227 (Proteasome)
    1. PS51475 (PROTEASOME...)
    1. SSF56235 (N-termina...)

Protein sequence

>MIA_05556_1
MKAVENAGTSIGIKFKDGVVFAVEKIINSKLLVPGSNKRLQTIDKHVGVAYSGLLPDGRHFVNRGRDDARSWRDLYKSQI
PVSTLADHMGGYAQAYTLYNSVRPFGVTAIVGGVDSKGPHLYMIEPSGTYWGYRGAATGKGRQTATSELEKLDFGSLTAE
EAVKEAAKIIYLAHEDSKDKDFELEISWVSTSATGGVHQYVPEALLEEAKQYAINEIEGDDGDEMEE

GO term prediction

Biological Process

GO:0051603 proteolysis involved in cellular protein catabolic process

Molecular Function

GO:0004298 threonine-type endopeptidase activity

Cellular Component

GO:0005839 proteasome core complex