MIA_05546_1

Protein

Length

530 amino acids

Protein function

EGGNOG:	0PHM9	PKA1	camp-dependent protein kinase
SGD closest match:	S000006124	TPK2	cAMP-dependent protein kinase type 2
CGD closest match:	CAL0000181882	TPK2	cAMP-dependent protein kinase catalytic subunit

Protein alignments

	%id	Aln length
MCA_02075_1	90.462%	346	MCA_02075_1
A0A167FQA5_9ASCO	87.572%	346	cAMP-dependent protein kinase catalytic subunit TPK2 OS=Sugiyamaella lignohabitans GN=TPK2 PE=4 SV=1
A0A060T576_BLAAD	91.185%	329	ARAD1B02112p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B02112g PE=3 SV=1
A0A1E3PTB6_9ASCO	86.957%	345	Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45095 PE=3 SV=1
Q6CCL9_YARLI	89.666%	329	YALI0C08305p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C08305g PE=3 SV=1
A0A0J9XJA2_GEOCN	84.615%	351	Similar to Saccharomyces cerevisiae YPL203W TPK2 cAMP-dependent protein kinase catalytic subunit OS=Geotrichum candidum GN=BN980_GECA24s00714g PE=3 SV=1
KAPB_YEAST	83.030%	330	cAMP-dependent protein kinase type 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPK2 PE=1 SV=2
UniRef50_P06245	83.030%	330	cAMP-dependent protein kinase type 2 n=80 Tax=Fungi TaxID=4751 RepID=KAPB_YEAST
A0A1D8PHU1_CANAL	82.583%	333	cAMP-dependent protein kinase catalytic subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TPK2 PE=3 SV=1
A0A1E4TA68_9ASCO	77.143%	350	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_124337 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6747
Predicted cleavage: 247

Protein family membership

None predicted.

Domains and repeats

Domain
202 - 503
Protein kinase-like domain (IPR011009)
Protein kinase domain (IPR000719)
Domain
475 - 530
AGC-kinase, C-terminal (IPR000961)

1 50 100 150 200 250 300 350 400 450 500 530

Detailed signature matches

IPR011009

Protein kinase-like domain
1. SSF56112 (Protein k...)
  
  202 - 503
  
  SUPERFAMILY
  SSF56112 (Protein kinase-like (PK-like))
IPR000719

Protein kinase domain
1. PS50011 (PROTEIN_KI...)
  
  220 - 474
  
  PROSITE profiles
  PS50011 (PROTEIN_KINASE_DOM)
2. SM00220 (serkin_6)
  
  220 - 474
  
  SMART
  SM00220 (serkin_6)
3. PF00069 (Pkinase)
  
  220 - 474
  
  Pfam
  PF00069 (Pkinase)
IPR000961

AGC-kinase, C-terminal
1. SM00133 (pkinase_C_6)
  
  475 - 530
  
  SMART
  SM00133 (pkinase_C_6)
2. PS51285 (AGC_KINASE...)
  
  475 - 530
  
  PROSITE profiles
  PS51285 (AGC_KINASE_CTER)
IPR017441

Protein kinase, ATP binding site
1. PS00107 (PROTEIN_KI...)
  
  226 - 249
  
  PROSITE patterns
  PS00107 (PROTEIN_KINASE_ATP)
IPR008271

Serine/threonine-protein kinase, active site
1. PS00108 (PROTEIN_KI...)
  
  339 - 351
  
  PROSITE patterns
  PS00108 (PROTEIN_KINASE_ST)

no IPR

Unintegrated signatures

G3DSA:1.10.51...

293 - 494

GENE3D
G3DSA:1.10.510.10 (G3DSA:1.10.510.10)
G3DSA:3.30.20...

144 - 292

GENE3D
G3DSA:3.30.200.20 (G3DSA:3.30.200.20)
cd05580 (STKc_PKA_like)

218 - 508

CDD
cd05580 (STKc_PKA_like)
mobidb-lite (disord...)

142 - 208

MobiDB Lite
mobidb-lite (disorder_prediction)

1 - 128

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

ATP binding site c...

226L

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

227G

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

228T

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

229G

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

230S

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

231F

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

232G

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

234V

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

247A

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

249K

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

281I

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

297M

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

298D

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

299Y

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

300I

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

304E

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

343D

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

345K

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

347E

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

348N

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

350L

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

360T

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

361D

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)

505F

ATP binding site
226L, 227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 281I, 297M, 298D, 299Y, 300I, 304E, 343D, 345K, 347E, 348N, 350L, 360T, 361D, 505F
CDD
cd05580 (STKc_PKA_like)
active site cd05580

227G

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

228T

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

229G

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

230S

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

231F

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

232G

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

234V

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

247A

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

249K

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

259M

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

281I

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

297M

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

298D

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

300I

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

304E

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

306F

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

310R

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

343D

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

345K

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

346P

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

347E

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

348N

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

350L

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

360T

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

361D

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

364F

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

375L

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

377G

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

378T

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

379P

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

380D

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

407E

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

411G

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

412Y

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

413T

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

416Y

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

417D

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

418H

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

420P

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

423T

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

505F

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)

508Y

active site
227G, 228T, 229G, 230S, 231F, 232G, 234V, 247A, 249K, 259M, 281I, 297M, 298D, 300I, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 348N, 350L, 360T, 361D, 364F, 375L, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 505F, 508Y
CDD
cd05580 (STKc_PKA_like)
polypeptide substr...

228T

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

230S

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

231F

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

259M

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

260R

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

261Q

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

304E

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

306F

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

310R

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

343D

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

345K

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

346P

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

347E

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

364F

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

375L

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

376C

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

377G

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

378T

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

379P

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

380D

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

407E

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

411G

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

412Y

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

413T

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

416Y

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

417D

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

418H

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

420P

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

423T

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

424Y

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)

508Y

polypeptide substrate binding site
228T, 230S, 231F, 259M, 260R, 261Q, 304E, 306F, 310R, 343D, 345K, 346P, 347E, 364F, 375L, 376C, 377G, 378T, 379P, 380D, 407E, 411G, 412Y, 413T, 416Y, 417D, 418H, 420P, 423T, 424Y, 508Y
CDD
cd05580 (STKc_PKA_like)
regulatory subunit...

230S

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

260R

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

261Q

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

263E

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

264H

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

304E

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

306F

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

310R

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

345K

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

346P

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

347E

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

364F

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

373W

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

374T

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

375L

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

376C

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

377G

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

378T

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

381Y

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

388T

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

389T

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

407E

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

420P

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

421M

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

424Y

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

425E

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

428L

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)

508Y

regulatory subunit interface
230S, 260R, 261Q, 263E, 264H, 304E, 306F, 310R, 345K, 346P, 347E, 364F, 373W, 374T, 375L, 376C, 377G, 378T, 381Y, 388T, 389T, 407E, 420P, 421M, 424Y, 425E, 428L, 508Y
CDD
cd05580 (STKc_PKA_like)
activation loop (A...

360T

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

361D

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

362F

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

363G

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

364F

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

365A

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

366K

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

367E

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

368V

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

372T

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

373W

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

374T

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

375L

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

376C

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

377G

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

378T

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

379P

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

380D

activation loop (A-loop)
360T, 361D, 362F, 363G, 364F, 365A, 366K, 367E, 368V, 372T, 373W, 374T, 375L, 376C, 377G, 378T, 379P, 380D
CDD
cd05580 (STKc_PKA_like)

Protein sequence

>MIA_05546_1
MATQNSHHPNNPASASANSSPPPAAASAGVASPDNFNNFSSPLASSTSTTPSSSKHRIHHHFHHFHHSPSPAQPPKPATS
LLKRANTTGHSAKPSAPPDSSSSSLLTSLRKTLSKDTGSSTPKMASSNPAAAAAASALAAQSGPAQASTNPAAQSAATTA
AAQHQQTPPSDKTAAKPSPNASGISPATAAGQPELTPATASSQLPKRSTVSKGKYTLSDFQILRTLGTGSFGRVHLVRSV
HNNRYYAIKVLKKVQIVRMRQVEHTNDERRMLKLVEHPFLIRMWGTFQDSKNLFMVMDYIEGGELFSLLRKSQRFPNPVA
KFYAAEVTLALEYLHSHNIIYRDLKPENILLDKNGHIKITDFGFAKEVVDVTWTLCGTPDYIAPEVVTTKAYNKSVDWWS
LGILIYEMLTGYTPFYDHTPMKTYEKILVGRVEYPSFLNPDAVDLLQRLITKDLTRRLGNLQGGSQDVKTHPWFAEVIWD
KLLSKDIETPYEPPIQSGVGDTSLFDRYPEEELDYGVSSPDPYANLFTDF

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding

Cellular Component