MIA_05518_1

Protein

Length

4,948 amino acids

Protein function

EGGNOG:	0PFRP	MIDASIN	Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (By similarity)
SGD closest match:	S000004096	MDN1	Midasin
CGD closest match:	CAL0000174407	MDN1	Midasin

Protein alignments

	%id	Aln length	E-value
MCA_02096_1	61.743%	4326	0.0	MCA_02096_1
A0A0J9XJA7_GEOCN	54.855%	4315	0.0	Midasin OS=Geotrichum candidum GN=BN980_GECA18s02100g PE=3 SV=1
UniRef50_A0A0J9XJA7	54.855%	4315	0.0	Midasin n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJA7_GEOCN
A0A1E3PRE0_9ASCO	47.295%	4362	0.0	Midasin (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_13250 PE=4 SV=1
A0A060T1F5_BLAAD	43.859%	4291	0.0	Midasin OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20064g PE=3 SV=1
A0A1D8PL61_CANAL	42.438%	4324	0.0	Midasin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDN1 PE=3 SV=1
A0A167F6U5_9ASCO	53.809%	2704	0.0	AAA family ATPase midasin OS=Sugiyamaella lignohabitans GN=MDN1 PE=4 SV=1
MDN1_YEAST	54.747%	2296	0.0	Midasin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDN1 PE=1 SV=1
Q6CFC5_YARLI	51.220%	2296	0.0	Midasin OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08338g PE=3 SV=1
A0A1E4TCD1_9ASCO	41.917%	532	1.17e-104	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58337 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0030

Protein family membership

Midasin (IPR012099)

Domains and repeats

Domain
297 - 562
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
636 - 976
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,044 - 1,312
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,345 - 1,622
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,729 - 1,981
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
2,014 - 2,295
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
4,732 - 4,947
von Willebrand factor, type A (IPR002035)
Domain
310 - 432
ATPase, dynein-related, AAA domain (IPR011704)
649 - 699
ATPase, dynein-related, AAA domain (IPR011704)
807 - 891
ATPase, dynein-related, AAA domain (IPR011704)
1,076 - 1,211
ATPase, dynein-related, AAA domain (IPR011704)
1,361 - 1,407
ATPase, dynein-related, AAA domain (IPR011704)
1,451 - 1,552
ATPase, dynein-related, AAA domain (IPR011704)
1,736 - 1,874
ATPase, dynein-related, AAA domain (IPR011704)
2,173 - 2,267
ATPase, dynein-related, AAA domain (IPR011704)

1 500 1000 1500 2000 2500 3000 3500 4000 4500 4948

Detailed signature matches

IPR012099

Midasin
1. PIRSF010340 (Midasin)
  
  23 - 4,948
  
  PIRSF
  PIRSF010340 (Midasin)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  297 - 562
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,466 - 1,622
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,345 - 1,409
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,044 - 1,312
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  636 - 697
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  806 - 976
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,729 - 1,981
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  2,014 - 2,092
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  2,187 - 2,282
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR003593

AAA+ ATPase domain
1. SM00382 (AAA_5)
  
  1,732 - 1,883
  
  SMART
  SM00382 (AAA_5)
  
  2,041 - 2,295
  
  SMART
  SM00382 (AAA_5)
  
  307 - 453
  
  SMART
  SM00382 (AAA_5)
  
  1,072 - 1,217
  
  SMART
  SM00382 (AAA_5)
  
  645 - 901
  
  SMART
  SM00382 (AAA_5)
  
  1,358 - 1,561
  
  SMART
  SM00382 (AAA_5)
IPR011704

ATPase, dynein-related, AAA domain
1. PF07728 (AAA_5)
  
  2,173 - 2,267
  
  Pfam
  PF07728 (AAA_5)
  
  310 - 432
  
  Pfam
  PF07728 (AAA_5)
  
  1,736 - 1,874
  
  Pfam
  PF07728 (AAA_5)
  
  1,076 - 1,211
  
  Pfam
  PF07728 (AAA_5)
  
  1,361 - 1,407
  
  Pfam
  PF07728 (AAA_5)
  
  807 - 891
  
  Pfam
  PF07728 (AAA_5)
  
  649 - 699
  
  Pfam
  PF07728 (AAA_5)
  
  1,451 - 1,552
  
  Pfam
  PF07728 (AAA_5)
IPR002035

von Willebrand factor, type A
1. SSF53300 (vWA-like)
  
  4,739 - 4,939
  
  SUPERFAMILY
  SSF53300 (vWA-like)
2. G3DSA:3.40.50...
  
  4,732 - 4,947
  
  GENE3D
  G3DSA:3.40.50.410 (G3DSA:3.40.50.410)
3. PS50234 (VWFA)
  
  4,740 - 4,936
  
  PROSITE profiles
  PS50234 (VWFA)

no IPR

Unintegrated signatures

Coil

1,408 - 1,438

COILS
Coil (Coil)

4,567 - 4,587

COILS
Coil (Coil)

4,476 - 4,521

COILS
Coil (Coil)

4,329 - 4,349

COILS
Coil (Coil)

4,124 - 4,148

COILS
Coil (Coil)

776 - 796

COILS
Coil (Coil)

2,674 - 2,701

COILS
Coil (Coil)
G3DSA:3.40.50...

2,031 - 2,278

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

1,067 - 1,217

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

636 - 897

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

1,724 - 1,880

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

1,330 - 1,561

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

291 - 467

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
cd00009 (AAA)

300 - 456

CDD
cd00009 (AAA)

1,073 - 1,211

CDD
cd00009 (AAA)

1,733 - 1,876

CDD
cd00009 (AAA)

1,344 - 1,419

CDD
cd00009 (AAA)
cd01460 (vWA_midasin)

4,683 - 4,947

CDD
cd01460 (vWA_midasin)
mobidb-lite (disord...)

4,082 - 4,654

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Walker A motif cd0...

315G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

316E

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

317G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

318G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

319S

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

320G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

321K

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

322T

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)
ATP binding site c...

316E

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

317G

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

318G

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

319S

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

320G

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

321K

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

322T

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

323F

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

385E

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)

432N

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 432N
CDD
cd00009 (AAA)
Walker B motif cd0...

381W

Walker B motif
381W, 382V, 383L, 384V, 385E, 386D
CDD
cd00009 (AAA)

382V

Walker B motif
381W, 382V, 383L, 384V, 385E, 386D
CDD
cd00009 (AAA)

383L

Walker B motif
381W, 382V, 383L, 384V, 385E, 386D
CDD
cd00009 (AAA)

384V

Walker B motif
381W, 382V, 383L, 384V, 385E, 386D
CDD
cd00009 (AAA)

385E

Walker B motif
381W, 382V, 383L, 384V, 385E, 386D
CDD
cd00009 (AAA)

386D

Walker B motif
381W, 382V, 383L, 384V, 385E, 386D
CDD
cd00009 (AAA)
arginine finger cd...

447R

arginine finger
447R
CDD
cd00009 (AAA)
Walker A motif cd0...

1,080G

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)

1,081P

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)

1,082T

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)

1,083S

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)

1,084S

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)

1,085G

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)

1,086K

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)

1,087T

Walker A motif
1,080G, 1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T
CDD
cd00009 (AAA)
ATP binding site c...

1,081P

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,082T

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,083S

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,084S

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,085G

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,086K

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,087T

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,088S

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,147D

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)

1,191Q

ATP binding site
1,081P, 1,082T, 1,083S, 1,084S, 1,085G, 1,086K, 1,087T, 1,088S, 1,147D, 1,191Q
CDD
cd00009 (AAA)
Walker B motif cd0...

1,143W

Walker B motif
1,143W, 1,144I, 1,145V, 1,146L, 1,147D, 1,148E
CDD
cd00009 (AAA)

1,144I

Walker B motif
1,143W, 1,144I, 1,145V, 1,146L, 1,147D, 1,148E
CDD
cd00009 (AAA)

1,145V

Walker B motif
1,143W, 1,144I, 1,145V, 1,146L, 1,147D, 1,148E
CDD
cd00009 (AAA)

1,146L

Walker B motif
1,143W, 1,144I, 1,145V, 1,146L, 1,147D, 1,148E
CDD
cd00009 (AAA)

1,147D

Walker B motif
1,143W, 1,144I, 1,145V, 1,146L, 1,147D, 1,148E
CDD
cd00009 (AAA)

1,148E

Walker B motif
1,143W, 1,144I, 1,145V, 1,146L, 1,147D, 1,148E
CDD
cd00009 (AAA)
arginine finger cd...

1,210R

arginine finger
1,210R
CDD
cd00009 (AAA)
Walker A motif cd0...

1,366G

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)

1,367E

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)

1,368T

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)

1,369G

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)

1,370C

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)

1,371G

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)

1,372K

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)

1,373T

Walker A motif
1,366G, 1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T
CDD
cd00009 (AAA)
ATP binding site c...

1,367E

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)

1,368T

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)

1,369G

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)

1,370C

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)

1,371G

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)

1,372K

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)

1,373T

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)

1,374T

ATP binding site
1,367E, 1,368T, 1,369G, 1,370C, 1,371G, 1,372K, 1,373T, 1,374T
CDD
cd00009 (AAA)
Walker A motif cd0...

1,740G

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)

1,741S

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)

1,742P

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)

1,743G

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)

1,744V

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)

1,745G

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)

1,746K

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)

1,747T

Walker A motif
1,740G, 1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T
CDD
cd00009 (AAA)
ATP binding site c...

1,741S

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,742P

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,743G

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,744V

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,745G

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,746K

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,747T

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,748S

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,810D

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)

1,855N

ATP binding site
1,741S, 1,742P, 1,743G, 1,744V, 1,745G, 1,746K, 1,747T, 1,748S, 1,810D, 1,855N
CDD
cd00009 (AAA)
Walker B motif cd0...

1,806W

Walker B motif
1,806W, 1,807V, 1,808L, 1,809L, 1,810D, 1,811E
CDD
cd00009 (AAA)

1,807V

Walker B motif
1,806W, 1,807V, 1,808L, 1,809L, 1,810D, 1,811E
CDD
cd00009 (AAA)

1,808L

Walker B motif
1,806W, 1,807V, 1,808L, 1,809L, 1,810D, 1,811E
CDD
cd00009 (AAA)

1,809L

Walker B motif
1,806W, 1,807V, 1,808L, 1,809L, 1,810D, 1,811E
CDD
cd00009 (AAA)

1,810D

Walker B motif
1,806W, 1,807V, 1,808L, 1,809L, 1,810D, 1,811E
CDD
cd00009 (AAA)

1,811E

Walker B motif
1,806W, 1,807V, 1,808L, 1,809L, 1,810D, 1,811E
CDD
cd00009 (AAA)
arginine finger cd...

1,869S

arginine finger
1,869S
CDD
cd00009 (AAA)
metal ion dependen...

4,746D

metal ion dependent adhesion site (MIDAS)
4,746D, 4,748S, 4,750S, 4,817T, 4,854D
CDD
cd01460 (vWA_midasin)

4,748S

metal ion dependent adhesion site (MIDAS)
4,746D, 4,748S, 4,750S, 4,817T, 4,854D
CDD
cd01460 (vWA_midasin)

4,750S

metal ion dependent adhesion site (MIDAS)
4,746D, 4,748S, 4,750S, 4,817T, 4,854D
CDD
cd01460 (vWA_midasin)

4,817T

metal ion dependent adhesion site (MIDAS)
4,746D, 4,748S, 4,750S, 4,817T, 4,854D
CDD
cd01460 (vWA_midasin)

4,854D

metal ion dependent adhesion site (MIDAS)
4,746D, 4,748S, 4,750S, 4,817T, 4,854D
CDD
cd01460 (vWA_midasin)

Protein sequence

>MIA_05518_1
MEAPLCFDPHLAFSSFEKLCQSKGLVLPTAVQPLTLSNYETQVSYLSSHALDTRFASLIQATHRPIFIDIAARWVSSPSV
EKSFIQSTNSPEPPINGFYTFLAIARAVSITPEVLPLTHEIIKSTLIFKNFNANYEQFGDRNVLEFLIALQRLVAFDYDA
FSSFISPDICEKLISHPWNSIKYLAIQLLAAYLTASDKIKKQMISQNIGQDVAIMGPYENSNEVDYLFFNTIEAKRISLE
RNLISEISVPNPTALFNIPSKNLSPLVSNLAGILIAQSSSQSYDGSKFVPTVGAVSSIRKIATALHTSRPVLLTGEGGSG
KTFYLEEAAKYFSKDDSIVRIHLGDQSDVKILVGTYSIGDKPGSFEWRPGILTIAVMEGRWVLVEDIEKAPTDVLSVLLP
LLEKRELLIPSRGETIKAASQFQIFGTVRTVNRTNGAPIIPEIIGKRLWEQVDVTPPTLEELKLIIRNRFPILANFSEKF
VDAYHTIIQTFAQSKFIALNRSTQNRPITSRDLIKWAHRVYLILRENGVTDPNQPINSALYDHIFAEAVDCFTGFIPNLD
ASKYLISIIGECLEIPSHRVDLFVQNHIPVFTRSNTNVTIGRASLERKRLLSKSKQKQKAQQIANFADTNHALRLLEKIG
VAVAMKEPTLLVGETGTGKTTVVQHLSALLNRDITVINVSQQTESSDLLGGYKPIDSKTIAMPLKEQFDLIFESTFSSKK
NEKFFALLTKCFSKSQWGNCVKLWREAIKLARTLLNPPEPEENAPKKRRKLSESDVAELQQKWNNFSEQIDKFEVQIKQS
DKSFLFSFVEGSLVQAVRRGDWVLLDEVNLASPETLESIADLLAESPSITLSEKGDAESIKAHPDFRLFACMNPATDIGK
RDLPTGLRSRFTELYVHSPDTNRNDLLSIIDKYIGHISITDAMVVNDVADLYLTAKKLSESNSIVDGANQRPHFSIRTLS
RTLTYSAKIAPIYQLRRSLYEGFCMSFSTLLDKKSTEILLPIIEKYTIQKLKNAKSVMSQIPPHPKDDHEYIQFRHYWLK
KGAFEPEEQPDYIITPYVEKNLLNLTRATAGGKFPILIQGPTSSGKTSMINYLAKKTGHKFVRINNHEHTDLQEYLGSYV
SDAEGKLAFQEGVLVQAVRNGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQEIVRPHPDFMLFATQNPPGLYGGR
KVLSRAFRNRFLELHFDDIPVNELEDILTRRCHIAPSYSKKIVEVYKQLSVNRQSTRVFEQKNSFATLRDLFRWAGREAI
GYDQLAANGYMLLGERVRKKEERVIVKEVLEKVMRVKLDIEAIYKSFEPTEIIGAASSVVWTQGMKKLAVLVSQALRYNE
PVLLVGETGCGKTTICQVLADAAGKSLHIVNAHQNTETGDIIGSQRPVRNRSEMLDNLQQELQKLLNTTGTLDDLREQYE
AADKSSFSEESIQRIVDLENHLKILFEWSDGSLIQALKFGDFFLLDEISLADDSVLERLNSVLEPERTILLAEKGSKDSS
ITAIDGFQFFATMNPGGDYGKKELSPALRNRFTEIWVPSMENMDDVLQIITSKLEPALKPLGHVLVQFSEWFGKTYGAGD
ASSGVISLRDMLAWVGFANKLCDSIGNELSILHGASMVFIDSIGTNSTAALAETPELLKSKKLECVKKLSELLKTDLTSS
YLEKFLVDVTDDKVSVGPFSLERTNAASKVSFNLQAPTTANNAMRVLRGMQVKKPMLLEGSPGVGKTSLITAIAEVTGHK
LTRINLSEQTDLIDLFGSDSPAEGEGSNQFVWRDAPFLHAMQEGGWVLLDEMNLASQSVLEGLNACLDHRGETYIPELDR
TFKCHPEFTVFAAQNPQYQGGGRKGLPKSFVNRFTVVYIDVLSTDDLKMISQYLYPNIPADVINKMISFILELDTEVSVK
RSFGHIGSPYEFNLRDTMRWLKLLTTQDPLSSNYGPEEFIDIIAKDRFRTKSDREFVEKIYTKHFGPFTKRSEFFQISEE
YVQAGHSCIVRNSLREPTYPHILPLQCNIQALETAITCVNNSWPLIIVGPTKSGKTNLIRYLAQVTGHELEEFAMNGDID
SMDLLGGFDQVDMNQKCSKVIQELIEICLDASCKFFGEFAATDIDPMFELLTYLKVVKISPETIEKISNTLPKVIELCPS
YASQLTPLLEKIDDVKEKLHIVNQARFEWFDGTLLQAVETGKWLVLDNANLCNPSVLDRLNSLLEPNGSLIVNECSLPSG
EPRVVKPHENFRLFLTMDSKYGELSRAMRNRGAELYLDAISNRATPFDRQLLQLEQPQTLESLDSQLSSLSLKSLALPSS
SFIKASDSFSRAFSLLEDSNSFSETINSFLTSLELSLLPRNYAFFLKSWVSNILSLDYYTATERERITSFSSYVSLALQT
PLQSTLDSLFGDNELPESISKSQFFNPVINSYVSNKAKANKNGLTASDVAVILYCIPLLNQVKVALDKCESSVHTLKPSS
FTYLERSAAKHFEKPLKNPAKVDVYAMINAIYHFISNVVYQCMTSPVSDLTEPLFSLVLLLQIGVDLTTLSSSTTTDESQ
LPVYRDILDDWYNKRGSADIFTTEETKLKNAISEFGCQLDLTSGTSMKLIWSQCHEEVPSSLNSWSRYERVISVAQKFDS
VSASLFSNSLDTIRSLQSSVIQTINAALKSSSENSELDDLIQKLESGIDLLQQQAANFEVQRKHYFDNGFVHISQIIELS
SLLDPSIRVEAYRILGNISYNAKYSTYHLSKYERQNVQLPYPPLFDSLWRYEDGELTASAIDFVNNGIGQLLLSYTNKID
NVASQDRNQAILDFQTLTETVVSQSKYLVKDHLNQFSQLLYLTILQFIEVHSVSIANLPTDISGLSPEVISQIFSSVSQS
ENINFVSAFEKYILNALKHLTDSSKISTARAWVYFALGMLVLYVPNIPFDPAIHQHVAFDRSVSQKSLSEEVSSCWSYLK
SIFVSPENFELEDCWNNRIPQPSSEDAPTIYRPSVSQIGAIYDEWNSLLTILPESLVLSLLDENKDVSLHLDQIKNLQRN
TTQFILRMNSNFKQYSDITSLLNSFIYAMKLGLDIFASIDRSPSFKPYSLIDPTQILDSSRLVEIFSLIKTDVTKLPDDI
SNPLLLCLLGTTNLMHKTRIESVKSIKTQSDLDEIIVFVFRSFYYKWSLTKMRDETAEAAKQSVFQDNSEQEVEDDFKRM
FPDYEDVLSLEDSSKHKGEDTYSDLVQIYLQTFGESSISISEVILRNVKFLQEYCKTHAHQFIADNLTNVLPAITKLLSN
TIQGQDSSDSLESPYDFYHSPRPEETVKFTTLALKVKAQIDKFLEIWPEHATLQHIAANCEDILALPLMSPIARYLVKVE
QIYELLDGWEKSASKDYSVMAISQEVANAIVSVRKLELSSLPRLLDLEEVNSIKEMSVQWFTLFELLLGNTTQLDEDNEE
STKLAASIVQNLTTFVSHSNYGQFDSRMKLLAAFSEHTNQLSEQYPVLAQVSESIKNVINFYEPLSKKVSAHIIDSRKAL
MKEVKDIVDLVRWKDTTVLALKQSIKKSHYKVHKVVRKYRDVLSASIEPIASAGLDQLPEADAVALISLELTPTAAYNSI
TKHLELAKKIPQWKSRSSHLSDVEQTANNMHKFILKVQAEELPDLEDFATEIISDMNRLRDATPKVLNEDTKKEVSTLKM
QKSNLLTTAIKELRRSGLKTTVRADVKERQTLMTSIMSSVPSLTGAHIGKSNTYFYKIIDLVPRLRVAAISSESDAPQAD
IQRGLAISENILSLILQQRSTVATLLENNGSLETLLAAINSVATLLNGEDKIQSSHLMPIVQSSSLAVAWVPKLMAFAID
SCKSASFVGKISTVDTKVFQDISETFVDLAIRFKRYQPLLSNMLVTQSIEELVSQLKSEFSSAILEITKWNQTNVSLAFI
GQVVVQWIQDQLLYLSFDIKSTDSDDVPTLEILEEKVKTISKSSMVVIQNIVGTTSEEITTEADNWFVKSQTRLGNYTRQ
LHQQKMIDLIREVIHIVANISFKSPENSSKAIALVGTLVPFFKEYKVLCDLIQDKLLHTMNRNNKTFYILMGALNSISTN
GFCTPQEESKDDNTETTSTGTGLGDGAGDANSKEDIDQDEGLTEDAQTENKEQEKDDAKDENEEDNAVEMEGDMAGELED
ASDQEKSDDEEDDKDDDEMDEEVGDVDDLDPNAIDEKMWDEEGDDNNKEKESDKVPENNNQDNLQANEDDGEANEDNENQ
DGKDGEESKEGDEENDDEEEEDDAAEQDDAVKHDEGEQLEDNVPESEVLDLPEEINLDGDDGKEEENDQDDEMEDVNMDD
AMDVDTEDKKKEDEKNDEEEGAMSEVEGEEDKNQPEVDKESDEMEVDGEDADQEREENEKDEEGTTEKDVMEENDENEEN
ESGKPQQNEMENNMEGLDGPDQSVDDQTANEENAVSQDASANKGEGSNYQTEEEQDNLENNGGTSSSNPEETKNEEKEEE
AVNDEARKNVEESMKQLGDALKEYYDRKKDIKEASDEQQQESEDTSSANQNPDEFEHVDGDSSAHETQALGSASHDHRQR
IDETKAIEEEEQEDGTAEENREVQDEEMPDSHDEEAPTGEQNTDMSSHAQSMVGERMRQDDDEEGGAEAQHEVLDDEDVD
MRDPDDPLYDGAEPGFEPARTIEEARELWQTNETVVQESALALTEQLRLILEPTQATKLRGDFKTGKRLNMKRIIPYIAS
QFKKDKIWMRRTKPSKRQYQIMIAVDDSKSMAESQAARLAFQSIALISKALTQLEAGQLAIARFGESTQVVHPFERPFSS
DSGAHVLQWFGFEQTKTDVKQLVQKSIGLFEEAEARGFQSGGGELWRLEIIISDGMCESHEALRRLVRKAREQRIMVVFV
VVDGLNNQGSILEMKDVQYDGDTGEMKIERYLDHFPFEYYIIVKEIRELPNVLSLVLRQFFSEVAESS

GO term prediction

Biological Process

GO:0000027 ribosomal large subunit assembly

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity

Cellular Component

GO:0005634 nucleus

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Entry type

Status

Per-residue features