MCA_02096_1

Protein

Length

4,962 amino acids

Gene name: MDN1

Description: Midasin

Browser: contigB:219436-234325+

RNA-seq: read pairs 1361, FPKM 3.4, percentile rank 14.5% (100% = highest expression)

Protein function

Annotation:		MDN1	Midasin
KEGG:	K14572	MDN1	midasin
EGGNOG:	0PFRP	MIDASIN	Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (By similarity)
SGD closest match:	S000004096	MDN1	Midasin
CGD closest match:	CAL0000174407	MDN1	Midasin

Protein alignments

	%id	Aln length	E-value
MIA_05518_1	61.59%	4319	0.0	MIA_05518_1
A0A0J9XJA7_GEOCN	52.61%	4357	0.0	Midasin OS=Geotrichum candidum GN=BN980_GECA18s02100g PE=3 SV=1
UniRef50_A0A0J9XJA7	52.61%	4357	0.0	Midasin n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XJA7_GEOCN
A0A1E3PRE0_9ASCO	46.29%	4353	0.0	Midasin (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_13250 PE=4 SV=1
A0A060T1F5_BLAAD	43.33%	4320	0.0	Midasin OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20064g PE=3 SV=1
MDN1_YEAST	42.43%	4360	0.0	Midasin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDN1 PE=1 SV=1
A0A1D8PL61_CANAL	42.70%	4326	0.0	Midasin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDN1 PE=3 SV=1
A0A167F6U5_9ASCO	53.62%	2708	0.0	AAA family ATPase midasin OS=Sugiyamaella lignohabitans GN=MDN1 PE=4 SV=1
Q6CFC5_YARLI	51.40%	2253	0.0	Midasin OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08338g PE=3 SV=1
A0A1E4TCD1_9ASCO	43.44%	465	4e-109	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58337 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0001

Protein family membership

Midasin (IPR012099)

Domains and repeats

Domain
291 - 526
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
643 - 971
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,044 - 1,313
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,345 - 1,624
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
1,731 - 1,980
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
2,045 - 2,290
P-loop containing nucleoside triphosphate hydrolase (IPR027417)
AAA+ ATPase domain (IPR003593)
4,751 - 4,953
von Willebrand factor, type A (IPR002035)
Domain
310 - 435
ATPase, dynein-related, AAA domain (IPR011704)
649 - 702
ATPase, dynein-related, AAA domain (IPR011704)
808 - 892
ATPase, dynein-related, AAA domain (IPR011704)
1,077 - 1,212
ATPase, dynein-related, AAA domain (IPR011704)
1,362 - 1,415
ATPase, dynein-related, AAA domain (IPR011704)
1,465 - 1,554
ATPase, dynein-related, AAA domain (IPR011704)
1,738 - 1,877
ATPase, dynein-related, AAA domain (IPR011704)
2,190 - 2,273
ATPase, dynein-related, AAA domain (IPR011704)

1 500 1000 1500 2000 2500 3000 3500 4000 4500 4962

Detailed signature matches

IPR012099

Midasin
1. PIRSF010340 (Midasin)
  
  33 - 4,962
  
  PIRSF
  PIRSF010340 (Midasin)
IPR027417

P-loop containing nucleoside triphosphate hydrolase
1. SSF52540 (P-loop co...)
  
  2,046 - 2,096
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  2,193 - 2,290
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,468 - 1,624
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,345 - 1,410
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  291 - 526
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  807 - 971
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  643 - 698
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,044 - 1,313
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
  
  1,731 - 1,980
  
  SUPERFAMILY
  SSF52540 (P-loop containing nucleoside triphosphate hydrolases)
IPR003593

AAA+ ATPase domain
1. SM00382 (AAA_5)
  
  307 - 482
  
  SMART
  SM00382 (AAA_5)
  
  1,359 - 1,563
  
  SMART
  SM00382 (AAA_5)
  
  1,073 - 1,218
  
  SMART
  SM00382 (AAA_5)
  
  646 - 902
  
  SMART
  SM00382 (AAA_5)
  
  1,735 - 1,886
  
  SMART
  SM00382 (AAA_5)
  
  2,045 - 2,288
  
  SMART
  SM00382 (AAA_5)
IPR011704

ATPase, dynein-related, AAA domain
1. PF07728 (AAA_5)
  
  808 - 892
  
  Pfam
  PF07728 (AAA_5)
  
  2,190 - 2,273
  
  Pfam
  PF07728 (AAA_5)
  
  1,077 - 1,212
  
  Pfam
  PF07728 (AAA_5)
  
  310 - 435
  
  Pfam
  PF07728 (AAA_5)
  
  1,738 - 1,877
  
  Pfam
  PF07728 (AAA_5)
  
  649 - 702
  
  Pfam
  PF07728 (AAA_5)
  
  1,362 - 1,415
  
  Pfam
  PF07728 (AAA_5)
  
  1,465 - 1,554
  
  Pfam
  PF07728 (AAA_5)
IPR002035

von Willebrand factor, type A
1. SSF53300 (vWA-like)
  
  4,751 - 4,953
  
  SUPERFAMILY
  SSF53300 (vWA-like)
2. PS50234 (VWFA)
  
  4,752 - 4,950
  
  PROSITE profiles
  PS50234 (VWFA)
IPR025662

Sigma-54 interaction domain, ATP-binding site 1
1. PS00675 (SIGMA54_IN...)
  
  650 - 663
  
  PROSITE patterns
  PS00675 (SIGMA54_INTERACT_1)

no IPR

Unintegrated signatures

Coil

4,498 - 4,522

COILS
Coil (Coil)

2,686 - 2,713

COILS
Coil (Coil)

4,248 - 4,279

COILS
Coil (Coil)

4,382 - 4,402

COILS
Coil (Coil)

4,342 - 4,362

COILS
Coil (Coil)
G3DSA:3.40.50...

1,727 - 1,883

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

297 - 455

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

1,067 - 1,218

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

1,352 - 1,560

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

2,037 - 2,284

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)

637 - 898

GENE3D
G3DSA:3.40.50.300 (G3DSA:3.40.50.300)
cd00009 (AAA)

649 - 674

CDD
cd00009 (AAA)

1,068 - 1,212

CDD
cd00009 (AAA)

300 - 456

CDD
cd00009 (AAA)

1,724 - 1,879

CDD
cd00009 (AAA)

1,357 - 1,457

CDD
cd00009 (AAA)
mobidb-lite (disord...)

4,095 - 4,619

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

Walker A motif cd0...

315G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

316E

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

317G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

318G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

319S

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

320G

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

321K

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)

322T

Walker A motif
315G, 316E, 317G, 318G, 319S, 320G, 321K, 322T
CDD
cd00009 (AAA)
ATP binding site c...

316E

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

317G

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

318G

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

319S

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

320G

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

321K

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

322T

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

323F

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

385E

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)

435K

ATP binding site
316E, 317G, 318G, 319S, 320G, 321K, 322T, 323F, 385E, 435K
CDD
cd00009 (AAA)
Walker B motif cd0...

382V

Walker B motif
382V, 383L, 384I, 385E, 386D
CDD
cd00009 (AAA)

383L

Walker B motif
382V, 383L, 384I, 385E, 386D
CDD
cd00009 (AAA)

384I

Walker B motif
382V, 383L, 384I, 385E, 386D
CDD
cd00009 (AAA)

385E

Walker B motif
382V, 383L, 384I, 385E, 386D
CDD
cd00009 (AAA)

386D

Walker B motif
382V, 383L, 384I, 385E, 386D
CDD
cd00009 (AAA)
arginine finger cd...

449R

arginine finger
449R
CDD
cd00009 (AAA)
Walker A motif cd0...

654G

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)

655E

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)

656T

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)

657G

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)

658T

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)

659G

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)

660K

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)

661T

Walker A motif
654G, 655E, 656T, 657G, 658T, 659G, 660K, 661T
CDD
cd00009 (AAA)
ATP binding site c...

655E

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)

656T

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)

657G

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)

658T

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)

659G

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)

660K

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)

661T

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)

662T

ATP binding site
655E, 656T, 657G, 658T, 659G, 660K, 661T, 662T
CDD
cd00009 (AAA)
Walker A motif cd0...

1,081G

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)

1,082P

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)

1,083T

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)

1,084S

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)

1,085S

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)

1,086G

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)

1,087K

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)

1,088T

Walker A motif
1,081G, 1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T
CDD
cd00009 (AAA)
ATP binding site c...

1,082P

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,083T

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,084S

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,085S

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,086G

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,087K

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,088T

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,089S

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,148D

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)

1,192Q

ATP binding site
1,082P, 1,083T, 1,084S, 1,085S, 1,086G, 1,087K, 1,088T, 1,089S, 1,148D, 1,192Q
CDD
cd00009 (AAA)
Walker B motif cd0...

1,144W

Walker B motif
1,144W, 1,145I, 1,146V, 1,147L, 1,148D, 1,149E
CDD
cd00009 (AAA)

1,145I

Walker B motif
1,144W, 1,145I, 1,146V, 1,147L, 1,148D, 1,149E
CDD
cd00009 (AAA)

1,146V

Walker B motif
1,144W, 1,145I, 1,146V, 1,147L, 1,148D, 1,149E
CDD
cd00009 (AAA)

1,147L

Walker B motif
1,144W, 1,145I, 1,146V, 1,147L, 1,148D, 1,149E
CDD
cd00009 (AAA)

1,148D

Walker B motif
1,144W, 1,145I, 1,146V, 1,147L, 1,148D, 1,149E
CDD
cd00009 (AAA)

1,149E

Walker B motif
1,144W, 1,145I, 1,146V, 1,147L, 1,148D, 1,149E
CDD
cd00009 (AAA)
arginine finger cd...

1,211R

arginine finger
1,211R
CDD
cd00009 (AAA)
Walker A motif cd0...

1,367G

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)

1,368E

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)

1,369T

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)

1,370G

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)

1,371C

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)

1,372G

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)

1,373K

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)

1,374T

Walker A motif
1,367G, 1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T
CDD
cd00009 (AAA)
ATP binding site c...

1,368E

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)

1,369T

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)

1,370G

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)

1,371C

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)

1,372G

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)

1,373K

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)

1,374T

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)

1,375T

ATP binding site
1,368E, 1,369T, 1,370G, 1,371C, 1,372G, 1,373K, 1,374T, 1,375T
CDD
cd00009 (AAA)
Walker B motif cd0...

1,425N

Walker B motif
1,425N, 1,426L, 1,427F
CDD
cd00009 (AAA)

1,426L

Walker B motif
1,425N, 1,426L, 1,427F
CDD
cd00009 (AAA)

1,427F

Walker B motif
1,425N, 1,426L, 1,427F
CDD
cd00009 (AAA)
Walker A motif cd0...

1,743G

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)

1,744S

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)

1,745P

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)

1,746G

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)

1,747V

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)

1,748G

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)

1,749K

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)

1,750T

Walker A motif
1,743G, 1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T
CDD
cd00009 (AAA)
ATP binding site c...

1,744S

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,745P

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,746G

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,747V

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,748G

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,749K

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,750T

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,751S

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,813D

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)

1,858N

ATP binding site
1,744S, 1,745P, 1,746G, 1,747V, 1,748G, 1,749K, 1,750T, 1,751S, 1,813D, 1,858N
CDD
cd00009 (AAA)
Walker B motif cd0...

1,807G

Walker B motif
1,807G, 1,810V, 1,811L, 1,812L, 1,813D, 1,814E
CDD
cd00009 (AAA)

1,810V

Walker B motif
1,807G, 1,810V, 1,811L, 1,812L, 1,813D, 1,814E
CDD
cd00009 (AAA)

1,811L

Walker B motif
1,807G, 1,810V, 1,811L, 1,812L, 1,813D, 1,814E
CDD
cd00009 (AAA)

1,812L

Walker B motif
1,807G, 1,810V, 1,811L, 1,812L, 1,813D, 1,814E
CDD
cd00009 (AAA)

1,813D

Walker B motif
1,807G, 1,810V, 1,811L, 1,812L, 1,813D, 1,814E
CDD
cd00009 (AAA)

1,814E

Walker B motif
1,807G, 1,810V, 1,811L, 1,812L, 1,813D, 1,814E
CDD
cd00009 (AAA)
arginine finger cd...

1,872S

arginine finger
1,872S
CDD
cd00009 (AAA)

Protein sequence

>MCA_02096_1
MESPLKFDPNQAHIDFEKLCHKHNVPFPSRLDPPTIENYDSQINHLSSLALNHKYMWLIQAAYRPLFIDIVARWISNSHV
ESVFSASKQPFKQPPVKGFYIFLAICRGLHTTPEILPLVHKFISTTSIVENFQKSLDKFNKVEVLQMLVSIYRLLQYNDN
EFLHLIPVQTCENLLEYSYSPVKYLAIQLLGAFLKASEQTKLQMIQNHIGSDKSIQGQYDDVEEVDYFFLPSIEGKRIAL
ELNTINETTQSSTVLFNISNNLLSPLVANLAGVLVAHPFSPTYDKSRFVATDGAVSSIEKIAMAIHTSKPVLLTGEGGSG
KTFYLEEIAKYLSRDQNLVRIHLGDQSDVKILVGTYSVGSKPGSFEWRPGVLTVAVQEGRWVLIEDIDKAPTDILSILLP
LLEKRELLIPSRGETIKAANGFQIFGTVRTIPSTKQNSSSFVPEIIGKRLWYPINVTQPSVDELKHIIKERFPLLLNFAD
KFVDTYTTISQTFADPKFISLNKSSQSRLLTSKDLIKWSQRVTLLLQNNDIKDPNQALSSSIYDHIFAEAVDCFTAFIPH
IDALNYMTSVIGQCLDVPAHRVSLYIEKHVPQYFNNNNSITVGRALVQKKEILSLQKVSKSKKNSTFANTNHSLRLLEKI
GVSVSMREPVLLVGETGTGKTTVVQHLASLLNRHITVINVSQQTESSDLLGGYKPIDTKTIAVPIKEEFDRLFEATFSSR
KNEKFFSMATKFFIKSSWKNVVTLWKEAVKMALVMIQKTEPDQEAPKKRRKISQTDLKELGKQWNSFSEKVQNFEVQVKQ
NDKSFLFSFVEGSLVQAIRRGDWVLLDEVNLAPAETLETIADLITDSPSITLSEKGDAESIKAHPDFRLFACMNPATDIG
KRDLPAGLRSRFTELYVHSPDNNRADLESIISKYIGSISLNDARVVDDVAELYLTAKQLSESNSIVDGANQRPHFSIRTL
SRTLTYAARISPVYGLRRSLYEGFCMSFSTLLDKKSTDILLPIIEKYTILRLPNHKSVMSKVPEEPKDGASYIAFKHYWL
RQGSLEPEEQPDYIITPYVEKNLLNLTRAAAGDKFPILIQGPTSSGKTSMINYLAKKTGHKFVRINNHEHTDLQEYLGSY
VSDNKGKLSFQEGVLVTAVRNGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQEIVKPHPDFMIFATQNPPGLYGG
RKVLSRAFRNRFLELHFDDIPVDELEDILRQRCKIAPSYSKKIVEVYRQLSIQRQSTRVFEQKNSFATLRDLFRWAGREA
IGYEQLAANGYMLLAERVRKPEERKLVKQVLEKVMKVKLDIDAIYQKYEPTEVIANATEVVWTKGMRKLACLVHQALQYN
EPVLLVGETGCGKTTICQVLAHASKKSLHIINAHQNTETGDIIGSQRPVRNRSEMREKLLIELRNLFNSPEGSLEELEQQ
FNNTDKSSFDPDSVQRITDIQNHLKVLFEWADGSLIQSLKSGDFFLLDEISLADDSVLERLNSVLEPERTILLAEKGSSD
NYVTAADGFQFFATMNPGGDYGKKELSPALRNRFTEIWVPSMEDMNDVLQIIESKLTDQLKQFSNVFVDFAEWIGKIYGG
GDVTSGVISLRDMLAWVDFSNKLCTSIGNELSILHGASMVFIDSIGTNSSASLAETPALLKSRKLDCVKKLSELLKKDLE
EYYLQTYEVKVDEKYISVGPFSYPRNPEVSTDVSFNLQAPTTAENAMRVLRGMQVKKPLLLEGSPGVGKTSLITAIAEVT
GHKLTRINLSEQTDLIDLFGSDSPAEGEGSNQFVWRDAPFLHAMQAGEWVLLDEMNLASQSVLEGLNACLDHRGETYIPE
LDRTFKCHPNFTVFAAQNPQYQGGGRKGLPKSFINRFTVVYMDVLSLDDLKMISGYLYPQIPSDIIDKMIAFIQDLDVEV
AVKKSFGHLGSPYEFNLRDTMRWLKLLADEKNFLTAGFGPQEFIDIIAKDRFRTIKDREFVEKLYTKHFGSFTPRPPFFQ
INEKFIQSGHSYTNRLSYQQPKFSNVLALQCNIQPVETSLTCINNAWPLIVVGPTNSGKTSLIRYLAKITGSELEEFAMN
GDIDSMDLLGGFDQVDLNHKSFTIIQEIKDYCFEESCKKYAHANTSEVSARPFVDLLTHIENMTISHGSMKKLLDVLTSF
IDLVPEAKEFLEPLFVRISDIVFKLSQPSEARFEWFDGTLLKAVETGKWLVLDNANLCNPSVLDRLNSLLEPNGSLIVNE
CSLSNGEPRVVKPHKNFRLFMTMDSKYGELSRAMRNRGVELFLDSLSNRATSFDSQLLQLPNETLNSEIEIDKQLSLLSL
KSSSLIPSSKFIPSSDAICRFFSLLEDANFFSETVNSFLTSLEISFIPEDYLIYFSRWLSNISKLPIYNEDERSKVLSSY
SYLELVIKSQYKDALDSFYIDSKIPKELQDAQMLNPVLNKYVSIQASQSKTGLKRNDLAAILYIIPIISEIEAALNQALE
NSKIAKPSTFSYLDQSVANESGRIVKNSSSIKVFSLIKGISQFSQAIITQFLTKEVSDLRDSLFSLILLLQIAIDLIKLT
SKALSETDTSRFPVYRDILDGWIEKYGSQPSFSTQIDQLNADIQNFSRQLDLTTGHSMNLLWTQFHQKVPSSKNSWDRYK
RIQAISQKFDYVSNLLYSNSLSTIRSLQSSLLMTIQAIINSSSDQNTDLDEIIEKLETGIETLQQQSANFEVQRHHYFTD
GFSFIGKSLELFVSVNPASKEETVILLKDIAYNAQYATFHLADYTKKDILSPYPPLFDVLWNFDGSKYASMGTDLVNNKL
GHLLIQYSNTVDTVASQDRAQAVIDFQTLTSTAINYSDMIIKNHLSQFTQLFYVMVLRVIGAHGIEVSNMPDTATEFNDE
MIQTLSKSVLSSTDDEFKSIFTAYFVTALMQFKLSKLSLARSWILFSIGMMKLYVPNIPFDPAIHQHVLYDRTVSYKSLQ
EDIISSWKYFKSVLIHPDLNEIEKIWESYLPQPTVEKIPLVYRPTSSKIGSIFNEWHSLLSSIPEDLLISLIDENASING
RHDQIRNIQRNTTQFINRMNTNFREYSDISSIFHSAIYFLKLGLDIFSSIDSVDQFNPYSLVDPLTILNIENFENVFNLA
KQDINKLPSDISNNLMLCFLSNIDLIQKTGSLSSEDQSKLDEMTYFTYRSFYYKWSLDKMRQESAEASKQTIFKDNSEEE
VEEDFKRMFPDYEDLVSLDDAVKPKPQNVAYDLLQLYLTMFGSKHVTIGNAMTRNISFLKEFSKNYSDSFNYPSLTNIFP
AIVSLLASTIKGQQMDESGSEEPFDFYHSSRPEETVKFTSISLKIKNQIGKYLELWPEHATLQHINSVCDDILTLPLLSP
IPFYLVRLEQIYELLDGWEKSASKDYSVLKLSQDVAAIIISMRQLELSSWPKLFDLEEMKSISDMSSLWFHLYEVLIENI
SKLDAESIDQSYIGIVQSLTLFLSQSTYGQFNTRLELLKAFAIQAKTISNEIPAFSQVAECILNVVNFHHPFVKSVDAHL
KEIKRNLKKEIKDIINLVRWKDTTVTALKISVKKSHLKLHKVVRKYRDTLSGSINSIIQNGLDGISEIETSPYSSYVLSS
EPSYNSITQHLELFRKMPICKSRSSLLSNVEKTIESMHRFISVIEKENLLNFEEFAEDVINNMNRLRDETPKVLTEENKK
EVSALRMQKGNLLTSTLKELRRAGLKASVRADIRENQALMSNIMSSTKSFSEFPIGKSNGYFYKILDLFPKLRNAANAGE
SDAPLSDVQRGLAIAENMLAAILRQRKSTVTVLESTKLIGSQVELLSSLSSLLATQDKIVSSTVPIQYTSAIVSWVPKLM
KYAIEACENSNFLSKSNISLHPKVFSEISERFSDLQVRLKRFSSLTTEGLISESIVEIYNTICKELETSVESLIKWKQSN
KATSFISDMAIQWMNQQLDILSRKQISHDISLKSSSFSLDDLDQKIQTLSKSIMVIIQNFVSSTKVEITFEDDGWFVNTQ
TKLLSYSRQLHQKKITKSIKEIISIASSISCSNPDEFYNVISLIGTFLPFAKEYQTLCEVVENKLVFDMIKTNKTSYVLM
KALYMLATNGFCTPQEESKDENDETTGDGTGLGDGAGGKSNNDDVEQDEGLTEDAQTANKEQDDNDNDDDDDDDNAVEME
GDMAGELEDASDQDKTDDEEDDDDKDEDDIDEEVGDIDDLDPNALDEKMWDEEGEENQKEKKSDNMPQNSNGDNLQANED
DDSNEGDNNEESNENADQENDKTEKSEDVEEEEDATEQEDEVKQNDEGEQLENNVPESDMMDLPDDLNIDGENEDNQDED
DNLSDMEMDGMDEEEGEEEPNNKQTQQEQKATEDENAEDEQDIEPEEIDTNQEPELDLDNNNDQTDDELEEVEEGVEEEK
SEENQDIAEDADEKKDPESNESSDPNMKDQLEGLDGMEEAENEDSKEGENAAEQQDSTDKGKGSSEDADQEEENLEQDGA
SSSTKPIEDETEMDAKQNDKARNQVEESMKQLGDALKEYYDRKNDIQDAPEKDEDENETQGANQNPDEFQHIDGESSAND
TQALGSAAQDYHQKIDEDRAIEEEDQDMPDVEKQEDHKPANENIDSHEETKQGDSTEDQLQAVQSMVGSNEKNSLHEDGD
FATDAVDEEDIEMMDDANLLADGAEPGFEPSRDIDEARTLWQENESIVQESALALTEQLRLILEPTLATKLRGDFKTGKR
LNMKRIIPYIASQYKKDKIWMRRTKPSKRQYQVLISVDDSKSMAESPQTVRLAFQSIALIAKALTQLEAGQLAISRFGEK
TQLVHPFERPFSSDSGAHVLQWFGFQQTKTDVKQLVEKSIKLFESASFSAGSHINGSELWKLQIIVSDGICESHETLKRL
VRKAREEHIMMVFVIVDGINNQGSILEMKDVQYDPDTGDMKIERYLDHFPFEYYIIVKEIQELPNVLSLVLRQFFSEIAE
SS

GO term prediction

Biological Process

GO:0000027 ribosomal large subunit assembly

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity

Cellular Component

GO:0005634 nucleus

Filter view on

Entry type

Status

Per-residue features