Protein

MIA_05517_1

Length
352 amino acids


Browser: contig08:697651-698773+

Protein function

EGGNOG:0PFX3ERG20farnesyl pyrophosphate synthetase
SGD closest match:S000003703ERG20Farnesyl pyrophosphate synthase
CGD closest match:CAL0000188232ERG20Bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase

Protein alignments

%idAln lengthE-value
MCA_02097_187.644%3480.0MCA_02097_1
A0A0J9XES3_GEOCN82.659%3460.0Similar to Saccharomyces cerevisiae YJL167W ERG20 Farnesyl pyrophosphate synthetase OS=Geotrichum candidum GN=BN980_GECA12s02485g PE=3 SV=1
A0A1E3PR51_9ASCO76.163%3440.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81027 PE=3 SV=1
UniRef50_A0A0E9NR1471.307%3525.05e-175Uncharacterized protein n=2 Tax=Saitoella complicata NRRL Y-17804 TaxID=698492 RepID=A0A0E9NR14_9ASCO
FPPS_YEAST68.466%3521.87e-180Farnesyl pyrophosphate synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG20 PE=1 SV=2
A0A1E4TLZ6_9ASCO70.640%3447.61e-175Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_93315 PE=3 SV=1
A0A060T1X4_BLAAD68.497%3468.09e-173ARAD1C20086p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20086g PE=3 SV=1
Q6C6W3_YARLI68.023%3445.68e-171YALI0E05753p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E05753g PE=3 SV=1
A0A1D8PH78_CANAL67.330%3525.93e-167Bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG20 PE=3 SV=1
A0A167F685_9ASCO78.603%2293.30e-123Bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase OS=Sugiyamaella lignohabitans GN=ERG20 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0806

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 352

Detailed signature matches

    1. PF00348 (polyprenyl...)
    1. SSF48576 (Terpenoid...)
    1. PS00723 (POLYPRENYL...)
    2. PS00444 (POLYPRENYL...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG01017 (Polypre...)
  2. SFLDS00005 (Isopren...)
  3. cd00685 (Trans_IPPS_HT)

Residue annotation

  1. SFLDG01017
  2. substrate binding ...
  3. chain length deter...
  4. aspartate-rich reg...
  5. SFLDS00005
  6. catalytic residues...
  7. substrate-Mg2+ bin...
  8. active site lid re...
  9. aspartate-rich reg...

Protein sequence

>MIA_05517_1
MSTKTQTPKEKFEAVFPSIVDELEATLKKTNISPEAIEWYKKSLVYNSVGGKANRGLSVVDTYRLLKGKTLEELSDDEYK
RAAILGWCVELLQAYFLVADDMMDQSITRRGQPCWYRVPKVGNIAINDAFMLEAAIYILLKNHFKKESYYVDLIELFHDV
TFQTELGQLLDLLTAPEDEVDLSKFSLEKHSYIVTYKTAFYSFYLPVALAMYMAGISSEQDLKQANDILIPLGEYFQIQD
DYLDVYGDPAVIGKIGTDIQDNKCSWIINTALKIVTPEQRQILDENYGRKDAEKEKVVKKLFEELNVEKLYLDYEEKIVK
ELREKIAKVDESRGFKGAVLEAFLNKIYKRQK

GO term prediction

Biological Process

GO:0008299 isoprenoid biosynthetic process

Molecular Function

None predicted.

Cellular Component

None predicted.