Protein

MCA_02097_1

Length
350 amino acids

Gene name: ERG20

Description: Farnesyl pyrophosphate synthase

Browser: contigB:234826-235965-

RNA-seq: read pairs 6166, FPKM 217.1, percentile rank 89.0% (100% = highest expression)

Protein function

Annotation:ERG20Farnesyl pyrophosphate synthase
KEGG:K00787FDPS farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
EGGNOG:0PFX3ERG20farnesyl pyrophosphate synthetase
SGD closest match:S000003703ERG20Farnesyl pyrophosphate synthase
CGD closest match:CAL0000188232ERG20Bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase

Protein alignments

%idAln lengthE-value
MIA_05517_187.64%3480.0MIA_05517_1
A0A0J9XES3_GEOCN80.64%3460.0Similar to Saccharomyces cerevisiae YJL167W ERG20 Farnesyl pyrophosphate synthetase OS=Geotrichum candidum GN=BN980_GECA12s02485g PE=3 SV=1
A0A1E3PR51_9ASCO73.26%3440.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81027 PE=3 SV=1
FPPS_YEAST69.48%3440.0Farnesyl pyrophosphate synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG20 PE=1 SV=2
A0A060T1X4_BLAAD68.50%3469e-180ARAD1C20086p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20086g PE=3 SV=1
UniRef50_A0A0E9NR1469.19%3442e-171Uncharacterized protein n=2 Tax=Saitoella complicata NRRL Y-17804 TaxID=698492 RepID=A0A0E9NR14_9ASCO
Q6C6W3_YARLI67.44%3446e-176YALI0E05753p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E05753g PE=3 SV=1
A0A1E4TLZ6_9ASCO67.73%3441e-172Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_93315 PE=3 SV=1
A0A1D8PH78_CANAL65.99%3447e-171Bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG20 PE=3 SV=1
A0A167F685_9ASCO76.09%2301e-127Bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase OS=Sugiyamaella lignohabitans GN=ERG20 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0632

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 350

Detailed signature matches

  1. Family IPR000092
    Polyprenyl synthetase
    1. PF00348 (polyprenyl...)
  2. Domain IPR008949
    Isoprenoid synthase domain
    1. SSF48576 (Terpenoid...)
    2. G3DSA:1.10.60...
  3. SITE IPR033749
    Polyprenyl synthetase, conserved site
    1. PS00723 (POLYPRENYL...)
    2. PS00444 (POLYPRENYL...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG01017 (Polypre...)
  2. SFLDS00005 (Isopren...)
  3. cd00685 (Trans_IPPS_HT)

Residue annotation

  1. SFLDG01017
  2. substrate binding ...
  3. chain length deter...
  4. aspartate-rich reg...
  5. SFLDS00005
  6. catalytic residues...
  7. substrate-Mg2+ bin...
  8. active site lid re...
  9. aspartate-rich reg...

Protein sequence

>MCA_02097_1
MSAQTPKEKFEAVFPSIVEEFEKTLEKTNISPEATEWYKKSLVYNSVGGKANRGLSVIDTYRILKGKSLEELSDDEYKRA
AILGWCVELLQAYFLVADDMMDASVTRRGQPCWYRNPKVGMIAINDAFMLEAAIYILLKNHFKPEPYYVDLLELFHEVTF
QTELGQLLDLLTAPEDEVDLSKFSLAKHSYIVTYKTAYYSFYLPVALAMYMAGISSEEDLKQARDILLPLGEYFQIQDDF
LDVYGDPSVIGKIGTDIQDNKCSWVVNTALKIATPEQRAILDENYGRKDAAKEKIVKELFNDMDIKKLYYEYEEKIVTEL
KEKIAKVDESRGFKGEVLSAFLNKIYKRQK

GO term prediction

Biological Process

GO:0008299 isoprenoid biosynthetic process

Molecular Function

None predicted.

Cellular Component

None predicted.