Protein

MIA_05499_1

Length
113 amino acids


Browser: contig08:652798-653140-

Protein function

EGGNOG:0PRUPNHP6DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex
SGD closest match:S000002157NHP6BNon-histone chromosomal protein 6B
CGD closest match:CAL0000201490NHP6Non-histone chromosomal protein 6

Protein alignments

%idAln lengthE-value
A0A060SYZ3_BLAAD70.423%718.40e-32ARAD1A15532p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A15532g PE=4 SV=1
UniRef50_A0A060SYZ370.423%712.07e-28ARAD1A15532p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060SYZ3_BLAAD
A0A167EYL2_9ASCO59.459%1111.10e-31Nhp6bp OS=Sugiyamaella lignohabitans GN=NHP6B PE=4 SV=1
NHP6B_YEAST69.697%663.83e-31Non-histone chromosomal protein 6B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NHP6B PE=1 SV=3
NHP6_CANAL75.758%666.86e-31Non-histone chromosomal protein 6 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NHP6 PE=3 SV=1
A0A0J9X4V4_GEOCN63.158%768.28e-31Similar to Saccharomyces cerevisiae YBR089C-A NHP6B High-mobility group (HMG) protein, binds to and remodels nucleosomes OS=Geotrichum candidum GN=BN980_GECA02s06335g PE=4 SV=1
A0A1E3PEI4_9ASCO62.338%771.25e-30Non-histone chromosomal protein 6 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28285 PE=4 SV=1
NHP6_YARLI66.667%696.17e-30Non-histone chromosomal protein 6 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NHP6 PE=3 SV=1
A0A1E4THC9_9ASCO68.182%661.65e-29Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31873 PE=4 SV=1
MCA_00437_161.538%784.18e-28MCA_00437_1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0167

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 20 40 60 80 100 113

Detailed signature matches

    1. SM00398 (hmgende2)
    2. PS50118 (HMG_BOX_2)
    3. PF00505 (HMG_box)
    4. SSF47095 (HMG-box)
Unintegrated signatures no IPR
Unintegrated signatures
  1. PR00886 (HIGHMOBLTY12)
  2. cd01390 (HMGB-UBF_H...)
  3. mobidb-lite (disord...)

Residue annotation

  1. DNA binding site c...

Protein sequence

>MIA_05499_1
MPKEGSGRRRKDDLDGAAAPAPTKKGKKKDPNAPKRSLSAYMFFANEKRDEVRNENPGISFGQIGKVLGEKWKALSDEEK
QPYNDKAETDKKRYEAEMTLYKNNKQGVYAEPE

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.