Protein
MCA_00437_1
Length
103 amino acids
Gene name: NHP6A
Description: Non-histone chromosomal protein 6; contains HMG box domain
Browser: contigA:1380861-1381173+
RNA-seq: read pairs 1530, FPKM 181.8, percentile rank 86.9% (100% = highest expression)
Protein function
| Annotation: | NHP6A | Non-histone chromosomal protein 6; contains HMG box domain | |
|---|---|---|---|
| EGGNOG: | 0PRUP | NHP6 | DNA-binding protein that induces severe bending of DNA. Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex |
| SGD closest match: | S000002157 | NHP6B | Non-histone chromosomal protein 6B |
| CGD closest match: | CAL0000201490 | NHP6 | Non-histone chromosomal protein 6 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| NHP6B_YEAST | 64.20% | 81 | 7e-35 | Non-histone chromosomal protein 6B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NHP6B PE=1 SV=3 |
| UniRef50_P11633 | 64.20% | 81 | 2e-31 | Non-histone chromosomal protein 6B n=7 Tax=Saccharomyces TaxID=4930 RepID=NHP6B_YEAST |
| MIA_05499_1 | 66.28% | 86 | 1e-33 | MIA_05499_1 |
| A0A167EYL2_9ASCO | 65.82% | 79 | 2e-33 | Nhp6bp OS=Sugiyamaella lignohabitans GN=NHP6B PE=4 SV=1 |
| A0A1E3PEI4_9ASCO | 67.11% | 76 | 3e-32 | Non-histone chromosomal protein 6 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28285 PE=4 SV=1 |
| A0A1E4THC9_9ASCO | 61.11% | 90 | 7e-32 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31873 PE=4 SV=1 |
| NHP6_YARLI | 62.35% | 85 | 2e-31 | Non-histone chromosomal protein 6 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NHP6 PE=3 SV=1 |
| NHP6_CANAL | 64.10% | 78 | 1e-30 | Non-histone chromosomal protein 6 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NHP6 PE=3 SV=1 |
| A0A060SYZ3_BLAAD | 61.63% | 86 | 2e-29 | ARAD1A15532p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A15532g PE=4 SV=1 |
| A0A0J9X4V4_GEOCN | 60.98% | 82 | 3e-29 | Similar to Saccharomyces cerevisiae YBR089C-A NHP6B High-mobility group (HMG) protein, binds to and remodels nucleosomes OS=Geotrichum candidum GN=BN980_GECA02s06335g PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0070
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
10
20
30
40
50
60
70
80
90
103
Detailed signature matches
no IPR
Unintegrated signatures
-
-
PR00886 (HIGHMOBLTY12)
-
cd01390 (HMGB-UBF_H...)
-
mobidb-lite (disord...)
Residue annotation
-
DNA binding site c...
Protein sequence
>MCA_00437_1 MPKDDKPVKKARAKRQKKDPNAPKRYLSAYMHFANENRDTIRQENPEASFGQIGKLLGQKWNSLSAEEKAPYEDKAGVDK KRYEEEMAVWKSRPNAASKEDEE
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.