Protein

MIA_05475_1

Length
694 amino acids

Browser: contig08:584140-586225+

Protein function

EGGNOG:0PF8RHBS1Elongation factor
SGD closest match:S000001792HBS1Elongation factor 1 alpha-like protein
CGD closest match:CAL0000193151orf19.7144Ribosome dissociation factor GTPase

Protein alignments

%idAln lengthE-value
MCA_02120_154.039%5570.0MCA_02120_1
A0A060T253_BLAAD46.474%5532.40e-150ARAD1C22418p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22418g PE=4 SV=1
UniRef50_A0A060T25346.474%5535.93e-147ARAD1C22418p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T253_BLAAD
A0A161HHV5_9ASCO43.613%5482.43e-139Ribosome dissociation factor GTPase HBS1 OS=Sugiyamaella lignohabitans GN=HBS1 PE=4 SV=1
A0A1E3PQ39_9ASCO47.009%4682.94e-134Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49788 PE=4 SV=1
A0A1E4TAW7_9ASCO45.969%4593.68e-128Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57956 PE=4 SV=1
A0A0J9XB10_GEOCN43.709%4531.39e-121Similar to Saccharomyces cerevisiae YKR084C HBS1 GTPase with similarity to translation release factors OS=Geotrichum candidum GN=BN980_GECA07s05246g PE=4 SV=1
A0A1D8PRL2_CANAL40.711%5061.59e-108Ribosome dissociation factor GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7144 PE=4 SV=1
HBS1_YEAST38.053%4521.27e-104Elongation factor 1 alpha-like protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HBS1 PE=1 SV=2
Q6CFF3_YARLI39.078%4999.46e-104YALI0B07557p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B07557g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6080

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 694

Detailed signature matches

  1. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  2. Domain IPR000795
    Transcription factor, GTP-binding domain
    1. PS51722 (G_TR_2)
    2. PF00009 (GTP_EFTU)
    3. PR00315 (ELONGATNFCT)
  3. Domain IPR009000
    Translation protein, beta-barrel domain
    1. SSF50447 (Translati...)
  4. Domain IPR009001
    Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
    1. SSF50465 (EF-Tu/eEF...)
  5. Domain IPR004160
    Translation elongation factor EFTu/EF1A, C-terminal
    1. PF03143 (GTP_EFTU_D3)
  6. SITE IPR031157
    Tr-type G domain, conserved site
    1. PS00301 (G_TR_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.30.10
  2. G3DSA:3.40.50...
  3. cd01883 (EF1_alpha)
  4. cd04093 (HBS1_C_III)
  5. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd01883
  2. putative GEF inter...
  3. GTP/Mg2+ binding s...
  4. EF1Balpha binding ...
  5. Switch I region cd...
  6. G2 box cd01883
  7. G3 box cd01883
  8. Switch II region c...
  9. G4 box cd01883
  10. G5 box cd01883
  11. heterodimer interf...

Protein sequence

>MIA_05475_1
MSKLASLAKMRALKKVAQQESTDSSAAEPSTLQRSTPGAPVSSLNLLDKLQAKHSGATELSSLSSSSSLNSQSSTSSSSL
AKTKSSALQKLAARAPKINPALTKPTESKLKSLGNSTPTPTPSARSSEKSSPASTPLPISIFPEIDYNLTITPQARSSAL
FYTDCDSDSDAYSPRMSYSPNQHSNFLYPIESTPKVTKPFSSPSPDDTVLAAQSQSKGFVDEATAKSLANLKIDGAAPKK
LKYNVLEEIKKSKTKKPVLCFVVIGHVDAGKSTLMGRLLLDTGAVSKNTVAKYEKASKEIGKQSFALAWVMDKTDEERSR
GITVDVCSSIFETDKRHFTILDAPGHRDFVPNMIEGSSRADVALLVIDASPNAFESGFFSDGQTREHAIVARSLGIEQIV
VAVNKLDVADWSEARFQAIEEQLGAFLQRVGFQTENTTFVPCSGLSGINVTGKKQKLPEELSRWYKGPSVLQALEAQELP
ERDYAAPFRLRVIDVEAMPHMAQVVVSGRVDYGTVQEGQGLIAVPAPASGKQPIVKSIHNYDRERESIPWAKAGDYVELV
LTNILPDDLSSGTILCGAEGPAVGYTSKFVAKVTVFDMDKPILKGNTMVMHYAGSRAEVQVSKLVAVLEKNGKDEVAGKA
PRMIKGGQKARVQISVLNGRMIPIETFEQNRDLGRIILRREGKTVAVGVVESLK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.