Protein

MCA_02120_1

Length
675 amino acids

Gene name: HBS1

Description: Elongation factor 1 alpha-like protein

Browser: contigB:295078-298002-

RNA-seq: read pairs 3653, FPKM 66.8, percentile rank 71.5% (100% = highest expression)

Protein function

Annotation:HBS1Elongation factor 1 alpha-like protein
KEGG:K14416HBS1 elongation factor 1 alpha-like protein
EGGNOG:0PF8RHBS1Elongation factor
SGD closest match:S000001792HBS1Elongation factor 1 alpha-like protein
CGD closest match:CAL0000193151orf19.7144Ribosome dissociation factor GTPase

Protein alignments

%idAln lengthE-value
MIA_05475_153.67%5595e-179MIA_05475_1
A0A060T253_BLAAD42.38%5641e-122ARAD1C22418p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22418g PE=4 SV=1
UniRef50_A0A060T25342.38%5642e-119ARAD1C22418p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060T253_BLAAD
A0A161HHV5_9ASCO40.11%5664e-121Ribosome dissociation factor GTPase HBS1 OS=Sugiyamaella lignohabitans GN=HBS1 PE=4 SV=1
A0A1E3PQ39_9ASCO40.72%5011e-112Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49788 PE=4 SV=1
A0A0J9XB10_GEOCN39.25%5072e-103Similar to Saccharomyces cerevisiae YKR084C HBS1 GTPase with similarity to translation release factors OS=Geotrichum candidum GN=BN980_GECA07s05246g PE=4 SV=1
A0A1E4TAW7_9ASCO34.28%6362e-103Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57956 PE=4 SV=1
A0A1D8PRL2_CANAL36.22%5559e-90Ribosome dissociation factor GTPase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7144 PE=4 SV=1
Q6CFF3_YARLI42.06%3212e-71YALI0B07557p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B07557g PE=4 SV=1
HBS1_YEAST49.05%2632e-70Elongation factor 1 alpha-like protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HBS1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0043

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 675

Detailed signature matches

  1. Domain IPR015033
    HBS1-like protein, N-terminal
    1. PF08938 (HBS1_N)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR000795
    Transcription factor, GTP-binding domain
    1. PS51722 (G_TR_2)
    2. PF00009 (GTP_EFTU)
    3. PR00315 (ELONGATNFCT)
  4. Domain IPR009000
    Translation protein, beta-barrel domain
    1. SSF50447 (Translati...)
  5. Domain IPR009001
    Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
    1. SSF50465 (EF-Tu/eEF...)
  6. Domain IPR004160
    Translation elongation factor EFTu/EF1A, C-terminal
    1. PF03143 (GTP_EFTU_D3)
  7. SITE IPR031157
    Tr-type G domain, conserved site
    1. PS00301 (G_TR_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.40.30.10
  2. G3DSA:3.40.50...
  3. cd01883 (EF1_alpha)
  4. cd04093 (HBS1_C_III)
  5. mobidb-lite (disord...)

Residue annotation

  1. G1 box cd01883
  2. putative GEF inter...
  3. GTP/Mg2+ binding s...
  4. EF1Balpha binding ...
  5. Switch I region cd...
  6. G2 box cd01883
  7. G3 box cd01883
  8. Switch II region c...
  9. G4 box cd01883
  10. G5 box cd01883
  11. heterodimer interf...

Protein sequence

>MCA_02120_1
MARGTQLDFGDDDYEDYDDGNYDQGDYSDEDEPIDQDRLDLAVDQVLAGIGRRKINTEEIEDMILDSNWNVKEVIDTICR
EIKEPQKKKKKPTAGDDVGTKPSVSTTTSEKSGGVTVTQKNVSKVAKAFSESSPDDVVLQAQSQAKGFGSLNPDATAKAM
ALLKLKEKTGKFVPKLNVLDEIAKQKDTKEIHCFVVIGHVDAGKSTLMGRLLYESGNVSKHLIEKYEQASKNIGKQSFAF
AWVMDKTDDERNRGITVNVCSTNFETSKRKYTILDAPGHRDFVPNMIEGSSRADMALLVVDSSPNAFESGFFSDGQTKEH
AIVARSLGIDTIIVAVNKMDVLNWNQTRFEVIEEQLGEFLLKLGFKKENIVFVPCSGLTGENLVTRSNLAELSWYKGDSL
LNTIEEQKPVERDYTRPFRLRVLEVDVIPHTQQVVVSGRIDSGVIQQEQPVVVVPSGIETSIKSIKSLNENTQINSTGNS
SLSTTANNSSTDLTASRSSSTASLAQMAGTIPWAKAGDYVELGLTGVSAEDLHRGDFICAPDCPVSQAHKFVVKLTIFDT
EKPILKGTQLIIHAAGYQGQVKVSKLISVFEKTAESVKTKKSPRMLKGGQSGQVELTVMSSDSSDAGDNEEGGNNGARSN
GIPLETYTENKDLGRIILRREGTTLAVGIVEKIIN

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003924 GTPase activity
GO:0005525 GTP binding

Cellular Component

None predicted.