Protein

MIA_05470_1

Length
315 amino acids

Browser: contig08:576862-577924+

Protein function

EGGNOG:0PHBRPAN6pantoate-beta-alanine ligase
SGD closest match:S000001407PAN6Pantoate--beta-alanine ligase
CGD closest match:CAL0000174427PAN6Pantoate--beta-alanine ligase

Protein alignments

%idAln lengthE-value
MCA_02117_165.09%3188e-148MCA_02117_1
A0A0J9XAG1_GEOCN64.63%3114e-143Similar to Saccharomyces cerevisiae YIL145C PAN6 Pantothenate synthase OS=Geotrichum candidum GN=BN980_GECA07s05235g PE=3 SV=1
A0A167FTK9_9ASCO62.66%3169e-140Pantoate--beta-alanine ligase PAN6 OS=Sugiyamaella lignohabitans GN=PAN6 PE=3 SV=1
UniRef50_A0A167FTK962.66%3163e-136Pantoate--beta-alanine ligase PAN6 n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A167FTK9_9ASCO
A0A060T1P9_BLAAD61.15%3143e-133ARAD1C22506p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C22506g PE=3 SV=1
A0A1E3PPJ1_9ASCO52.27%3523e-117Pantoate--beta-alanine ligase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40523 PE=3 SV=1
Q6CFK9_YARLI52.55%3332e-115YALI0B06006p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B06006g PE=3 SV=1
A0A1D8PS97_CANAL54.13%3271e-112Pantoate--beta-alanine ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PAN6 PE=3 SV=1
PANC_YEAST48.59%3193e-92Pantoate--beta-alanine ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PAN6 PE=1 SV=2
A0A1E4TA57_9ASCO46.13%3231e-88Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_124325 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3955

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 315

Detailed signature matches

  1. Family IPR003721
    Pantoate-beta-alanine ligase
    1. MF_00158 (PanC)
    2. cd00560 (PanC)
    3. PF02569 (Pantoate_l...)
    4. TIGR00018
  2. Domain IPR014729
    Rossmann-like alpha/beta/alpha sandwich fold
    1. G3DSA:3.40.50...
  3. Domain IPR004821
    Cytidyltransferase-like domain
    1. TIGR00125
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.13...
  2. SSF52374 (Nucleotid...)

Residue annotation

  1. pantoate-binding s...
  2. ATP-binding site c...
  3. active site cd00560
  4. HXXH motif cd00560

Protein sequence

>MIA_05470_1
MTQSTTPVNVFRTIKEVRTWRRAALLEGKTVGLVPTMGALHQGHLNLVSQSVQNNDFTIVSIFVNPSQFAPHEDLDAYPR
TLDADIEALSTVPSHNPIAVFVPTVTEMYPSGIPLEQAKQRGAFVEVKGLSEQLEGSIRPQFFRGVATVVTKLLNIVTPE
VAYFGQKDIQQVVVVKRMVKDLLINTEIFMVPTVREHNLLAMSSRNTYLTPDSRAHSCILYQALAAGETLYKSGETSRAK
IMEAINAVIKPYEKTPDTPENQFAVDIEYISLADTVDLQEVDQVDPAVGAILSSAVRVPNKSGTETRIIDNIILH

GO term prediction

Biological Process

GO:0009058 biosynthetic process
GO:0015940 pantothenate biosynthetic process

Molecular Function

GO:0003824 catalytic activity
GO:0004592 pantoate-beta-alanine ligase activity

Cellular Component

None predicted.