Protein

MIA_05466_1

Length
865 amino acids

Browser: contig08:564894-567492+

Protein function

EGGNOG:0PHD9SGS1helicase
SGD closest match:S000004802SGS1ATP-dependent helicase SGS1
CGD closest match:CAL0000185821SGS1ATP-dependent DNA helicase

Protein alignments

%idAln lengthE-value
UniRef50_G8BT2443.430%4491.54e-105Uncharacterized protein n=1 Tax=Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) TaxID=1071381 RepID=G8BT24_TETPH
A0A0J9X742_GEOCN42.391%4608.37e-107Similar to Saccharomyces cerevisiae YMR190C SGS1 Nucleolar DNA helicase of the RecQ family OS=Geotrichum candidum GN=BN980_GECA04s02397g PE=4 SV=1
MCA_06405_141.270%4411.35e-99MCA_06405_1
SGS1_YEAST41.244%4346.84e-99ATP-dependent helicase SGS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SGS1 PE=1 SV=1
Q6BZP6_YARLI39.869%4597.56e-96YALI0F31977p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F31977g PE=4 SV=1
A0A060T609_BLAAD40.858%4431.15e-96ARAD1B15840p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B15840g PE=4 SV=1
Q5A5R4_CANAL41.531%4318.11e-96ATP-dependent DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SGS1 PE=4 SV=1
A0A167CYR1_9ASCO36.719%5125.03e-94ATP-dependent DNA helicase SGS1 OS=Sugiyamaella lignohabitans GN=SGS1 PE=4 SV=1
A0A1E4TE35_9ASCO39.723%4331.28e-98Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_24928 PE=4 SV=1
A0A1E3PG93_9ASCO38.494%4782.45e-92ATP-dependent DNA helicase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_27084 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1680
Predicted cleavage: 20

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 865

Detailed signature matches

  1. Family IPR004589
    DNA helicase, ATP-dependent, RecQ type
    1. TIGR00614
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  6. Domain IPR032284
    ATP-dependent DNA helicase RecQ, zinc-binding domain
    1. PF16124 (RecQ_Zn_bind)
  7. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00046 (DEXDc)
  4. cd00079 (HELICc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MIA_05466_1
MLPVNDNIKSASRGRTLRVRPRNEESSTSNRVASQSSKPIVTSSTPVYNDLFSPITITEEDLADNEWFTFSQQDLDNLRQ
KSLSEKQKNDQLEQLSDIISSVDVNDDDDLSIGDSTIDDMFSTIVPNEGTLQPTENSTSHETAVLSDDSDLGFDLDSNDS
FFNTLHDELNANNQATQVENNSGSLELVNRTESDIWNPKDPPSPPMCFDDYYIPMFDADPINQSDYQNNIPGADPDKPKP
SKVQDIVNIWKLDIPDHNEFWTFDPEALDFFSPEPLDPNSSTTFKRLSMAPQSIEDNETYPWTQEVNDIRSNIFHLDSFR
PNQLTAINATLNGKDTFVLMPTGGGKSLCYQLPACVKSGKTKGVTIVVSPLLALMADQVTTLKSLGVKAQELSSHTTLPE
RKKILDGIERSVIEILYMSPEMLYLLFFKDLSIEGKTEQEIKDSKETPRFKKFLRKGIFARIVLDEAHCVMWDFRKKYKY
VKYIKHILPEIPIMALTATVAIQEQHNILDCFRTRNPLILKSSYFRPNLNLSIKMKQSRSVIDNDIVTRLKTEFQGKSGI
IYCFSRRSCEDLCQHLLNNGISAGYFHSKAKKYQKLLALRLWKENKLQVICATTAFGMGIDKHDVRFVIFHALPRDLPNY
YQGVGRAGRDGKSSDCVVYLSLYDFLLVAGLNIIDNGVPEEAKVRSLQGIKDLNGFFQDFSTCRHARLVKFFGETPTFTT
CNNMCDNCEFQSRYDRRNCTAEDLHYLNSRKVQLRNLFQFLQRNFVDPRYSKHNFIGTMVHLPGQESEFSFLMMSMGLLD
FPGMQDKICKEIDALIQAEILLRYLKNSRKNIDSINVNMCFDLGFQTFSILIQGFVLDPVKAKVL

GO term prediction

Biological Process

GO:0006310 DNA recombination

Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity

Cellular Component

None predicted.