Protein

MIA_05443_1

Length
295 amino acids

Browser: contig08:486010-487009+

Protein function

EGGNOG:0PHI1PGUG_05047Spermidine synthase
SGD closest match:S000006273SPE3Spermidine synthase
CGD closest match:CAL0000181339SPE3Spermidine synthase

Protein alignments

%idAln lengthE-value
MCA_00737_191.156%2940.0MCA_00737_1
Q6C3P7_YARLI80.345%2901.18e-164YALI0E33143p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E33143g PE=3 SV=1
A0A060T393_BLAAD79.181%2932.56e-163ARAD1A07832p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A07832g PE=3 SV=1
A0A1E3PPV9_9ASCO78.425%2923.60e-162Putative spermidine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81934 PE=3 SV=1
A0A1E4TAF4_9ASCO77.855%2893.14e-161Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_127935 PE=3 SV=1
UniRef50_Q9Y8H774.828%2901.14e-147Spermidine synthase n=156 Tax=Eukaryota TaxID=2759 RepID=SPEE_NEUCR
A0A167F5P8_9ASCO73.973%2924.50e-151Spermidine synthase OS=Sugiyamaella lignohabitans GN=SPE3 PE=3 SV=1
Q59Z50_CANAL73.559%2951.10e-149Spermidine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPE3 PE=3 SV=1
SPEE_YEAST73.038%2933.48e-148Spermidine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPE3 PE=1 SV=1
A0A0J9XHU3_GEOCN63.605%2943.86e-128Similar to Saccharomyces cerevisiae YPR069C SPE3 Spermidine synthase involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid OS=Geotrichum candidum GN=BN980_GECA15s02364g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6247

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 295

Detailed signature matches

  1. Family IPR001045
    Spermidine/spermine synthases
    1. MF_00198 (Spermidin...)
    2. TIGR00417
  2. Family IPR030668
    Spermidine/spermine synthase, eukaryotes
    1. PIRSF000502 (Spermi...)
  3. Domain IPR035246
    Spermidine synthase, tetramerisation domain
    1. G3DSA:2.30.14...
    2. PF17284 (Spermine_s...)
  4. Domain IPR029063
    S-adenosyl-L-methionine-dependent methyltransferase
    1. SSF53335 (S-adenosy...)
  5. Domain IPR030374
    Polyamine biosynthesis domain
    1. PS51006 (PABS_2)
  6. SITE IPR030373
    Polyamine biosynthesis domain, conserved site
    1. PS01330 (PABS_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. PF01564 (Spermine_s...)
  3. cd02440 (AdoMet_MTases)

Residue annotation

  1. S-adenosylmethioni...

Protein sequence

>MIA_05443_1
MSTELTHPSIVDGWFREISDTMWPGEAMTLRVKKVLHAAKSKYQDVLVFESTDYGNVLVLDGAIQATERDEFSYQEMITH
LALNSHPNPKKVLVIGGGDGGVLREVVKHKCVEEAVLCDIDEMVPEVSKLYLKEMKKGFEDERVTVHIGDGFKFLAEYKN
TFDCIITDSSDPEGPAASLFQKPYFELLSEALTEKGVITTQAESIWLHLDIIKDLKKACKSVFPTVEYAYTTIPTYPSGQ
IGFMVCSKDPNATPKIPLRSFDEEENDKINKYYNKEIHSASFVLPTWARKALNEA

GO term prediction

Biological Process

GO:0006595 polyamine metabolic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.