Protein
MIA_05359_1
Length
1,247 amino acids
Browser: contig08:255787-259584+
Protein function
| EGGNOG: | 0PIYR | EPL1 | Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2 M |
|---|---|---|---|
| SGD closest match: | S000001870 | EPL1 | Enhancer of polycomb-like protein 1 |
| CGD closest match: | CAL0000195210 | EPL1 | Enhancer of polycomb-like protein 1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_05594_1 | 66.005% | 403 | 7.51e-137 | MCA_05594_1 |
| A0A0J9XHQ2_GEOCN | 70.056% | 354 | 2.09e-131 | Enhancer of polycomb-like protein OS=Geotrichum candidum GN=BN980_GECA15s01748g PE=3 SV=1 |
| A0A060TCS4_BLAAD | 63.099% | 355 | 9.27e-117 | Enhancer of polycomb-like protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D45320g PE=3 SV=1 |
| UniRef50_A0A060TCS4 | 63.099% | 355 | 2.29e-113 | Enhancer of polycomb-like protein n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A060TCS4_BLAAD |
| A0A1E3PRV2_9ASCO | 59.280% | 361 | 7.98e-110 | Enhancer of polycomb-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5639 PE=3 SV=1 |
| A0A161HI08_9ASCO | 56.684% | 374 | 5.39e-102 | Enhancer of polycomb-like protein OS=Sugiyamaella lignohabitans GN=EPL1 PE=3 SV=1 |
| EPL1_YARLI | 56.560% | 343 | 7.99e-83 | Enhancer of polycomb-like protein 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=EPL1 PE=3 SV=1 |
| A0A1E4TCX8_9ASCO | 50.716% | 349 | 1.37e-73 | Enhancer of polycomb-like protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_16291 PE=3 SV=1 |
| EPL1_CANAL | 42.822% | 411 | 5.80e-63 | Enhancer of polycomb-like protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EPL1 PE=3 SV=1 |
| EPL1_YEAST | 43.733% | 375 | 1.84e-62 | Enhancer of polycomb-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EPL1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.6256
Predicted cleavage: 24
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1247
Detailed signature matches
-
-
PF10513 (EPL1)
-
no IPR
Unintegrated signatures
-
-
mobidb-lite (disord...)
Protein sequence
>MIA_05359_1 MAPTTGSSARFRQRKISVKQTLQVLWQSDVPDLEDEQQRELQHVETGVEKGEEEEHHLQAAINASIAAATSGTNVEQVYI PTPDASKIWKDFSKYYKKGFSSPHSYIRQSSTVEDLSGCPYNMDEEDEVFLKKLNKGKTPSNQCSEDDFEMIMHKFETVI DEKQPYLSMDPSEVLSFEELAPVITEQLKESENDVNNPELLLTKLSTAQTAPTTRKSKKPPSAHFKMFGALIYPHWKERK IQRHGRSIAPTLKTEDNNKDDSDPYVCFRRREVRQVRKTRRTDTQSSEKLRKLRMELQAAKYLMEMIVQRESMRSDALQL EIEIFTSRVKMKDLKRSLNITGDEEDLVTHKKRKTGQAVVKEESQESATELAKQASTTMPAKAKALVTSGLSGVQNVAAT AVGASAAGSATGSAAAAAATSVLPPGAPTAAAAAAALAQQAQKQQLLQQQQLQAQQSQLQVKQSQAQAAALGQAHTVQNQ IPQSYPIHHVPQQTRLPVSKIPDMDLVSLDKILSNKEAAMKASIKEKLRRRAIEDKTWLNYTDNPFVPYCDYFDPDETTR NALTIIQPNHAAYSSIATAYPPAPDKCLKFPLASSLGQGYSSRLETNPYLLQTKINEKGGMDIVNKINDREGPWPDEGHN IPRGTAISLRRRFGRGGRIIVDRRGIVRRPKSIDEIYNLDPQESGRITKELEEWSSLGTFSGSSVEDTRQRSETLARLER LDDRYKYDSDVHFDNTEYSGGDPSKLNGISEGTQAIRFGAMLISKAYDNFWEVFKNRQQQLGAMHKKLQKHQQAQQQAQQ LAQQQQQQQQPQQQQQQRQPNQAQMAQPSVPAHLTQQHAASMHQAQQLLQQQIKQQMHNAAIKQQNAQQRLHPTQQQQRA SYIPANVQRQINHAAALQQQQQQQNIPSPQIQMKAKLASQQQQQQYISRSQSPSSPMMNSVTIDSKGKVAQSIATPTTAN ANFRAQTQSPQLYHHQQQQQQQQQAAAIAAASRHSPQLTHAGVGSQRSSPSMAFNTLNQFSPHGTVPSSPSTTTVLPNGN GVVRGTGVQGSPVMASPTMSNAVRRVATPQQQAQQQQQLLGMATNGASVINNPALQAQLHLLSQKQQQQQRVVAGATTAL QQQMRVATSQANGYPGNQNPAGTMASAAMAFTSDGATGNIVLASQGPQKQVQPQQQQMKSSPRLANMAATVSPTLTQQAL YQQIKNAGAGQSPLTGPHAAVVGFSPNHTVMRQQQAPSPAQQQPQKQ
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005515 protein binding
Cellular Component
None predicted.