Protein
MCA_05594_1
Length
1,032 amino acids
Gene name: EPL1
Description: Enhancer of polycomb-like protein 1
Browser: contigD:1756371-1759543-
RNA-seq: read pairs 1157, FPKM 13.8, percentile rank 32.2% (100% = highest expression)
Protein function
| Annotation: | EPL1 | Enhancer of polycomb-like protein 1 | |
|---|---|---|---|
| KEGG: | K11322 | EPC | enhancer of polycomb-like protein |
| EGGNOG: | 0PIYR | EPL1 | Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2 M |
| SGD closest match: | S000001870 | EPL1 | Enhancer of polycomb-like protein 1 |
| CGD closest match: | CAL0000195210 | EPL1 | Enhancer of polycomb-like protein 1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XHQ2_GEOCN | 56.87% | 742 | 0.0 | Enhancer of polycomb-like protein OS=Geotrichum candidum GN=BN980_GECA15s01748g PE=3 SV=1 |
| A0A161HI08_9ASCO | 46.48% | 796 | 0.0 | Enhancer of polycomb-like protein OS=Sugiyamaella lignohabitans GN=EPL1 PE=3 SV=1 |
| UniRef50_A0A161HI08 | 46.48% | 796 | 0.0 | Enhancer of polycomb-like protein n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A161HI08_9ASCO |
| MIA_05359_1 | 66.00% | 403 | 4e-140 | MIA_05359_1 |
| A0A1E3PRV2_9ASCO | 48.75% | 521 | 1e-122 | Enhancer of polycomb-like protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_5639 PE=3 SV=1 |
| A0A060TCS4_BLAAD | 61.58% | 354 | 1e-115 | Enhancer of polycomb-like protein OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D45320g PE=3 SV=1 |
| EPL1_YARLI | 56.52% | 345 | 3e-88 | Enhancer of polycomb-like protein 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=EPL1 PE=3 SV=1 |
| A0A1E4TCX8_9ASCO | 51.30% | 347 | 1e-84 | Enhancer of polycomb-like protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_16291 PE=3 SV=1 |
| EPL1_CANAL | 40.44% | 413 | 2e-61 | Enhancer of polycomb-like protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=EPL1 PE=3 SV=1 |
| EPL1_YEAST | 42.86% | 357 | 2e-60 | Enhancer of polycomb-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EPL1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.4954
Predicted cleavage: 24
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
800
900
1032
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_05594_1 MPKTTGTSARFRQRKISVKQTLQVLWQSEVPDLEDEQQRELQHVETGVEKGEEEEHHLQAAINASLAAATTGKVEHVYIP TPDASKISKDYSKYYKPGYTDPHTYIRQSDTVEDCSGCPYNMDEEDEIFFKTLNKNKSPSSQCTEDEFEMIMYQFEKIIA EKQPFLSVDPNQVLSYDELSGFIIEELKQKENDPTDPENLLQYLTSNQYKSKRAAMRLKLSTFKKFSPQIYTHWKERKIK RKGKSIIPTLKTEDQDKDDSDPYVCFRRRELRQVRKTRRTDTQSSEKLRKLHMEMEAARVLMEMVLKRENMRKEALELDR SIFESRVKMKVLKRSLKISGDEEDLVTHKKRKNAQTANALAVGVKDEKNGSVPASSATSPDGTSISASSAPGKATAHARA GSLATGPGVPPTTGDIAVARTLSSSQQSQQTTLQHQQQQHLHQQQQQAIINNPIHQVPANVRLPACKIPDIDLVSFDDVV RDKENFIKNLVKEKVKNRQQLDREWVNYTDSPFIPYCDYFDPDETSRNALKIIQPSNAAYSSITTTYPPHPDKHLRFPLS SSLGPGYSARFENHPYILNSRVNSDGNLEIISKINDQDVSARSSGGEDIPRGTSISVRKRAGRGGRILVDRRGIVKRPKS LDCLYDQDPQNNSVVEEELAKWSGLVTFDSNYTSNETEKSILRSRLERLDDRYKYDMDSSADRDYPGADPSRLNGISEET QAIRFGSMLMSKAYDSYWEAYRLRQQQLGMMKMLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQKQIQQLQNQQKQP QNQTHTQRPQANFTQRFSQNSPIPSSAHLKIVPTAQQQQQLNMKAKLAQQYQISRSQSPNVSHDGSVVVTTVPTTTGATA NGFISQTQSPPATYQQLQSAVPSPQLAQARVLNSQQVQRASSPITYNNLVNLQQQVAMNGNATTNALLQAQLQQLVQQQA ALNQQQKTSTNFTDLSSPVTTPQQIKSTNSPKLTTVVAAVATPTGNNGTSSSQNLNHQQQAMLYQQQQHMQY
GO term prediction
Biological Process
None predicted.
Molecular Function
None predicted.
Cellular Component
None predicted.