MIA_05328_1

Protein

Length

1,659 amino acids

Protein function

EGGNOG:	0PKA3		reverse transcriptase
CGD closest match:	CAL0000176110	orf19.7274	Uncharacterized protein

Protein alignments

	%id	Aln length	E-value
MCA_03180_1	39.924%	1057	0.0	MCA_03180_1
A0A167E5I2_9ASCO	35.854%	1071	0.0	Polyprotein of L1-like non-LTR retrotransposon Zorro 3 OS=Sugiyamaella lignohabitans GN=POL92 PE=4 SV=1
UniRef50_A0A167E5I2	35.854%	1071	0.0	Polyprotein of L1-like non-LTR retrotransposon Zorro 3 n=7 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167E5I2_9ASCO
A0A0J9XC44_GEOCN	28.968%	252	7.19e-22	Uncharacterized protein (Fragment) OS=Geotrichum candidum GN=BN980_GECA08s04349g PE=4 SV=1
A0A1D8PFY7_CANAL	25.556%	270	1.02e-12	Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7274 PE=4 SV=1
A0A060T0U2_BLAAD	52.000%	50	7.74e-09	ARAD1C18194p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C18194g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0217

Protein family membership

None predicted.

Domains and repeats

Domain
574 - 810
Endonuclease/exonuclease/phosphatase (IPR005135)
1,067 - 1,337
Reverse transcriptase domain (IPR000477)

1 200 400 600 800 1000 1200 1400 1659

Detailed signature matches

IPR005135

Endonuclease/exonuclease/phosphatase
1. SSF56219 (DNase I-like)
  
  592 - 807
  
  SUPERFAMILY
  SSF56219 (DNase I-like)
2. G3DSA:3.60.10.10
  
  574 - 810
  
  GENE3D
  G3DSA:3.60.10.10 (G3DSA:3.60.10.10)
3. PF14529 (Exo_endo_p...)
  
  687 - 802
  
  Pfam
  PF14529 (Exo_endo_phos_2)
IPR000477

Reverse transcriptase domain
1. PF00078 (RVT_1)
  
  1,089 - 1,336
  
  Pfam
  PF00078 (RVT_1)
2. PS50878 (RT_POL)
  
  1,067 - 1,337
  
  PROSITE profiles
  PS50878 (RT_POL)

no IPR

Unintegrated signatures

Coil

177 - 218

COILS
Coil (Coil)

287 - 307

COILS
Coil (Coil)

891 - 911

COILS
Coil (Coil)

855 - 875

COILS
Coil (Coil)

1,658 - 1,659

COILS
Coil (Coil)
G3DSA:1.20.5.170

153 - 251

GENE3D
G3DSA:1.20.5.170 (G3DSA:1.20.5.170)
G3DSA:3.30.70...

1,137 - 1,337

GENE3D
G3DSA:3.30.70.270 (G3DSA:3.30.70.270)
SSF56672 (DNA/RNA p...)

1,029 - 1,281

SUPERFAMILY
SSF56672 (DNA/RNA polymerases)
cd01650 (RT_nLTR_like)

1,080 - 1,337

CDD
cd01650 (RT_nLTR_like)
mobidb-lite (disord...)

1 - 26

MobiDB Lite
mobidb-lite (disorder_prediction)

95 - 138

MobiDB Lite
mobidb-lite (disorder_prediction)

52 - 75

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative NTP bindi...

1,166D

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)

1,167I

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)

1,168Q

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)

1,169G

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)

1,170A

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)

1,171F

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)

1,225Q

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)

1,257D

putative NTP binding site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,257D
CDD
cd01650 (RT_nLTR_like)
putative active si...

1,166D

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,167I

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,168Q

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,169G

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,170A

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,171F

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,225Q

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,226G

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,255F

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,257D

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,258D

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,333L

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)

1,334G

putative active site
1,166D, 1,167I, 1,168Q, 1,169G, 1,170A, 1,171F, 1,225Q, 1,226G, 1,255F, 1,257D, 1,258D, 1,333L, 1,334G
CDD
cd01650 (RT_nLTR_like)
putative nucleic a...

1,226G

putative nucleic acid binding site
1,226G
CDD
cd01650 (RT_nLTR_like)

Protein sequence

>MIA_05328_1
MPDPPDKNNPTTPSGNDPRADINNLDNHVEQTKINDIEKTIAVGLKQKGVSHLKGHHSHDVHHVKASPKIHKDDDKIDKI
ANLDKLQKKLDHLNKHPDHEHQENDPDSQMLDTTSDPDSPTENFSSGGDTEIDANNSRDIDINMADNITITPTHEIESVN
CISETLVAKVNSLAEILVEVNNKYDNMGKNCQSLKKENELLKKESEILTAENAVLRNKFAEFSLKFDQFEGSWNTLRSEV
DNLKSKEVHSEVKKITIEQIKKINSQKAEELANLAITDWTQRAAENKQTVKKEINHVKEITQNLEKRIDGIEYQVGTIST
KTDLASKEITYAKQEIKSAVRKVDTLPYKLTTRPSNSNPIKLKDIMKAQKQQREEQVANAKPIYRVCIRIPATANNIRRE
TIGAKIDSIAQKNVAEMVEFTTKGNLYVNINDKEFADRAAEWIPQIDPTFSLLDTEPWYKAKLLGVPEEATIQEVKDALY
TFGEYHIVLNNEPKVIYKNHDSQTILVCFRNVSDFAKCADKLVIRYTKIKVTPYVNRPKTPEQLRRIQMKNKKTKRLQMR
NPQKNLWMTQKLKNSWNLLQKKPQLLRIPLMIYKVFQLNCHKSKSITETILDEKEPDILLLQEPYFSKYGPINHKEWIPI
YAIAQNGNTPCRAITYIRSNSDLRAVTTKIEKLTNTDMVTIMVKDFTLVNVYNQPKPSKKFPEPPALEILKKEVQGQYDR
LIIAGDYNLHHREWETESNPDADTNEIVDWLHENDMMLITPPNRKTYRNKTTIDLVYCSVNLLHRIIFRKIDENSLSDHA
IVEWDLSFFQHQHEEEKLTSIERLNIQQANWDKFEQELSNAIKTLNVHDKALKSLDQIDSQAEILENVIKKAMASSMEKI
KLVRKSKRYWNAELRKKLEFALKAKREARLRQPTFALKKQKIQEAKEATRDFDRSLREASSEQWNKFLSGLEENDIWRVL
RYINPKGNDTIIPQIRKEDGTLTTTVEEKRHEIWKALLPEIDHGPDKHFEIDDDSRWPKLDIKEVEIALANTPNDKAAGD
DGITGLVLKKAWKNKDYQIRFFKLLQACVNFGYHPKVWRHGIIVVIPKPKKPDYSKPRAYRPISLLKIPSKVLEKIMQTR
MTKLTVKLLPPEQYGGRKGYCATDAVLELVQRIETSREKISAILIDIQGAFDNVNRNILAETMENMGLPNALISWTYQFI
SQREASMLMDRRKGPVQKISTGIPQGSPISPLLFLIYSTPMYKAIQQRGGKAFGFIDDVTITVEGTIDKNTELLSNILAK
CCEWAKSRMTKIDLGDKLGFIHFAKNIKANDQKAQLTLPNGEHLKPQKEVKLLGIILDNTLDFKSHIMSKITKARKAIGA
IWRLGGTFRGMRGSSVRSLYIACVRPIIEYGMEIWFHKILKGEIHKLEVAQNMALRRVVGAYRTTPIAVLQKEAGVMPYS
IRLNFMIARKAIRLHLNISNTNPIKEHLLTLIENSPIAKLTSVYLEAEEDRKVVIKNLMKTRKKPVFGPVTRELLQSQLI
AILKKQAIEKWRDAYWHSKKDQWYHDITAETPCSDNLSKMTTGVVMKKDSRRTLSFITQFRTGHGNFGAWFKKFGIQKDS
YDCECGELETVRHILVECPLLEEKRKGLRRISPEMDMSTLLNSLIGLQEIARFISVWRE

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MIA_05328_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component