Protein

MIA_05274_1

Length
1,845 amino acids


Browser: contig08:6689-12227+

Protein function

EGGNOG:0QDZFReverse transcriptase (RNA-dependent DNA polymerase)
CGD closest match:CAL0000185137orf19.2669Uncharacterized protein

Protein alignments

%idAln lengthE-value
UniRef50_A5DXY548.104%5012.48e-140Uncharacterized protein n=2 Tax=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) TaxID=379508 RepID=A5DXY5_LODEL
MCA_01665_139.315%4969.26e-100MCA_01665_1
A0A161HJI4_9ASCO29.293%4953.59e-57Gag-pol fusion protein OS=Sugiyamaella lignohabitans GN=AWJ20_4398 PE=4 SV=1
YCH4_YEAST38.380%2841.37e-61Putative transposon Ty5-1 protein YCL074W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TY5A PE=5 SV=2
A0A1D8PLS1_CANAL25.893%5603.37e-45Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2669 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1479
Predicted cleavage: 15

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1845

Detailed signature matches

    1. SM00343 (c2hcfinal6)
    2. SSF57756 (Retroviru...)
    3. PS50158 (ZF_CCHC)
    1. PF13976 (gag_pre-in...)
    1. SSF53098 (Ribonucle...)
    1. PF00665 (rve)
    2. PS50994 (INTEGRASE)
    1. PF07727 (RVT_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF56672 (DNA/RNA p...)
  2. TRANSMEMBRANE (Tran...)
  3. cd09272 (RNase_HI_R...)
  4. mobidb-lite (disord...)

Residue annotation

  1. active site cd09272
  2. RNA/DNA hybrid bin...

Protein sequence

>MIA_05274_1
MTTRVTVQQVMGRTSAYINLTSSEKLNPLNYHAWATKILLGLRAMNNGVHLYVEAGTVSPGPNESLDDLTASLDTVVHDV
ILNNISPELIEQVNDVAIRGRDLWLYLHQEYSQLQPADVISLMKSLYAVNIESGPKLVSSIRTHVATWRSIYQSLSPDSV
VAFNILASMSPNCERLIQYALEHRFDGNNADNLDINNFVRNADKWAKLLKLTGSPATLSTEAFSASSKRHGNRSRNNVLT
CFRCKKRGHTSNRCPASWDEAQAAQQDKDKDDKESKDGKSSRAWFAEAVDGFTQIVDDDSFVSYAFESKTSDVCEKFGID
CSESDDDSESELFDSSEPYNGDEDYFDYQVSESCSNSELDVVPAADPFLGCTEDPCFVSEPCVGSGDDPCDPESFIGSPI
ISFVPEPLVGSDDGVCLPCFDFLVDPVVDPSPCDIICLADPAVDPCSSVVDSLVDSVVEPFPSDVTSLADPIVDPSCFVT
HPSDTKKSRLSPLFYLFVFAFLLLSLILLVLLHLFPFLDLRQSVHQAFVAESAASAEAHLVVGPDTFDFIHDTGATSHIC
NNISYFTNLRPTSTTIRGLGSSSAKAVGDIVVDVLGRDGNPFDRVVLRDVLYVPNIPRNLFAARRAIAGGCQFIENLDHI
SAVENGTTRVHAIAMGDLYFCRFRVVLPSKPVHEVFAVEPFANLWHQRLGHASVEVLKKLSKSLSVKPTHFEVVDSHKCD
ACLGGKATSLPFTGTTEKATRPLELLVSDLSGPHVATPVGHRYVLTIMDFYSRYSYVELLVKKSDASLAIRNYIARCESY
FSGDSRGNRVSYFHSDNGGEYISKDLEQFFVSKGIKHTFTVPHTPQQNGVAERLNRTLFEKAKSMLLYAHAPDYLWGEAV
KCANYLRNRLPSRTTGGVCPLQLWTGKPPSYQHMRVFGCRANVVIADAKRESKLSSNIDPGVFVGYSLDRTAYRVLVDSS
IVEARDVYFDESQFPFMKSDKELSSNGSGIAFGIGCGSGSMSGPRADCNDSGTGSSVGLNSIAGSNSSSGSSFGSRRSLP
DVTSVSGSGSGSSASSTSGSTGSSPTCSPSPSLSPSPSLSSSPRSSSSLVVHKPRSVRRILPSSSAPLESPTLPSLPSSP
ILPSSDQDPSVSSPIGPSQSDLSQVGSPAGESDNSGDSGIPQRGGDIGFHPDVIASSPSPPSVELEIVPLDQEPPSSDLV
KSLDQAGVSVDTKDDTQAILPKSRSRVVAVRLPSVTPAKRPSSHDFVAPPSKHRCDDSAKQPASSVVPAKRRAEQESISY
RRLKSLRFEYDDVALLVFTDPTTFEQAMSSEDAEFWLEACVVEMSSLKRNRTWDLVDLPPGRKAINSKWVFKIKRKADGS
IERYKARLVCIGFSQVEGIDYTETFAPVVRYETVRIVLAIAAQFGFQVHHMDVETAFLNGDLKEDIYMRQPKGFIVKGQE
SKVCHLNKSLYGLKQAPLCWNEKIHGALVKLGFVRNESDYGVYTKGRGSAMVIIALYVDDLLIAGNSTQAIANTKSSLSS
MFKMKDLGLVEQFLGMRVKQSPYHITVDVCRYIVDMLEEFGMQNCSSVKTPLPTRDLSDFSESDAAADPSLYRSIIGKLI
YAANCARPDLAVAVSFLCRYMQNPKSMHMEAAKHTLRYLKGSAQLGLEYRAQKVYKLVGYSDADYAQDKQDRKSFTGYVF
ILSGGPITWACRKQVSPASSSVESEYMSLSDASKECFWINQLLSLCQIPVPLPVTMFEDNQGCIALAQNPVFHRRTKHID
VRYHVVRHYIRSGVIHLEYLDTQVMLADMFTKNLGRVKFETLRGLLGMKAVGDSATRGGVEHAMLSQTSACENCWEIMVD
GLCLF

GO term prediction

Biological Process

GO:0015074 DNA integration

Molecular Function

GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

Cellular Component

None predicted.