Protein
MIA_05269_1
Length
913 amino acids
Browser: contig07:1168431-1171173+
Protein function
| EGGNOG: | 0PHUD | LAS21 | Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose |
|---|---|---|---|
| SGD closest match: | S000003598 | LAS21 | GPI ethanolamine phosphate transferase 2 |
| CGD closest match: | CAL0000200443 | GPI7 | GPI ethanolamine phosphate transferase 2 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_03813_1 | 65.185% | 945 | 0.0 | MCA_03813_1 |
| A0A0J9XA45_GEOCN | 57.623% | 892 | 0.0 | Similar to Saccharomyces cerevisiae YJL062W LAS21 Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure OS=Geotrichum candidum GN=BN980_GECA06s04003g PE=4 SV=1 |
| A0A167EB56_9ASCO | 51.713% | 934 | 0.0 | Las21p OS=Sugiyamaella lignohabitans GN=LAS21 PE=4 SV=1 |
| UniRef50_A0A167EB56 | 51.713% | 934 | 0.0 | Las21p n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167EB56_9ASCO |
| A0A060T0D6_BLAAD | 50.877% | 912 | 0.0 | ARAD1C06490p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06490g PE=4 SV=1 |
| A0A1E3PHC3_9ASCO | 50.109% | 918 | 0.0 | Alkaline phosphatase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71169 PE=4 SV=1 |
| GPI7_YARLI | 44.457% | 911 | 0.0 | GPI ethanolamine phosphate transferase 2 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=LAS21 PE=3 SV=1 |
| A0A1E4TM24_9ASCO | 41.117% | 895 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1398 PE=4 SV=1 |
| GPI7_CANAL | 39.048% | 945 | 0.0 | GPI ethanolamine phosphate transferase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GPI7 PE=3 SV=3 |
| GPI7_YEAST | 33.631% | 895 | 5.43e-126 | GPI ethanolamine phosphate transferase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAS21 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8860
Predicted cleavage: 16
Protein family membership
Domains and repeats
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Domain
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Domain
1
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400
500
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700
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913
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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-
TRANSMEMBRANE (Tran...)
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cd16024 (GPI_EPT_2)
Residue annotation
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putative active si...
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metal binding site...
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putative substrate...
Protein sequence
>MIA_05269_1 MTLLTRWLSIISVLCLQLAALFYFGLGFFPKKLIIPGQASFFTDPSNEFPSPAPFNKLIFVVIDAFRSDFAFSTSSNMPF IHKSIRDGCALGYTAFSTPPTVTLPRLKGLTTGSTPNFLDAVLNIAEEDSSSTLLGQDSWVWQLYSSGKKIHMFGDDTWI KLFPGLFTEVDGTASFFVSDFTEVDNNVTRHIDDQISRSNEWDALILHYLGLDHIGHKGGPESVFMPNKQKEMDQIIKKL FDSMTEETLLVVVGDHGMNEVGNHGGSSAGETSAATVFFSKKIQNLPKDGLYTKTAPLPVSPDFTYYRRISQYDIVPTLS ALLNFPIPLNSLGVILKEFLPLWPTHDRDKVIFQNVLQISNILNSTYPGFMTIDADDSMFCQSQIDFNDVSELETLKCMW WKVKESGDFKDDKLVFDYLERSQKFLSQASSNYKTKEMGIGLILAGLSFLVSIVSSWKLLRSVPLIRFILLMITVLYSLS MFGSSLIEEEHHLWYWGATGWISWLYILTTRKKFTDGFDWVIGLIIVRIIRSWNQTGQKHAGEPDIASFLSKPENAAGLW FLIILYYGSLFERIWKGTFKNINQIAGFFFSFITIASSIAFKVNMACVSGDTVPTLIRKIGAFDNSIIDDPSKLISYARL SFVIIGMGMLYELSNVILYDPRHRQSQKPLTNMTTFLEALIAMQTRTKNIPLFIFFHMLRTYLVKAANKNFVFRSTNDLD NHNEERFSVRIISILSITILIFQHMSFFAMGNSNSLASIDLSNAYNGLSTYNIVIVGLLTFIGNWAGPLYWSATGLSILL EDDIRPEIIKAHLKFKRQEFEGSIGADNKNIDKKKLEDLNSLVGQDVVTLRIVLSQVFFSGFLFGILGACVALKDHLFIW TVFSPKLLYAAAWIVLQHCVLDVFTCTCFALLS
GO term prediction
Biological Process
GO:0008152 metabolic process
Molecular Function
GO:0003824 catalytic activity
Cellular Component
None predicted.