Protein

MIA_05265_1

Length
519 amino acids


Browser: contig07:1162191-1163911-

Protein function

EGGNOG:0PH8HFG04268.1NEDD8-activating enzyme E1 regulatory subunit
SGD closest match:S000005924ULA1NEDD8-activating enzyme E1 regulatory subunit
CGD closest match:CAL0000191482orf19.4153NEDD8-activating enzyme E1 regulatory subunit

Protein alignments

%idAln lengthE-value
MCA_03809_154.56%5260.0MCA_03809_1
A0A0J9X6A5_GEOCN49.91%5392e-164NEDD8-activating enzyme E1 regulatory subunit OS=Geotrichum candidum GN=BN980_GECA04s02474g PE=3 SV=1
UniRef50_A0A0J9X6A549.91%5393e-161NEDD8-activating enzyme E1 regulatory subunit n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6A5_GEOCN
A0A060SZD4_BLAAD41.65%5212e-138NEDD8-activating enzyme E1 regulatory subunit OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06622g PE=3 SV=1
A0A1E3PIK5_9ASCO43.94%5283e-136NEDD8-activating enzyme E1 regulatory subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83652 PE=3 SV=1
Q6C046_YARLI37.52%5252e-116NEDD8-activating enzyme E1 regulatory subunit OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27863g PE=3 SV=1
A0A167EIS0_9ASCO36.01%5365e-105NEDD8-activating enzyme E1 regulatory subunit OS=Sugiyamaella lignohabitans GN=ULA1 PE=3 SV=1
A0A1D8PN68_CANAL38.89%5403e-100NEDD8-activating enzyme E1 regulatory subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4153 PE=3 SV=1
A0A1E4TB78_9ASCO35.09%5131e-72NEDD8-activating enzyme E1 regulatory subunit OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3631 PE=3 SV=1
ULA1_YEAST26.69%5321e-31NEDD8-activating enzyme E1 regulatory subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ULA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0319

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 519

Detailed signature matches

    1. PIRSF039099 (APP-BP1)
    1. PF00899 (ThiF)
    2. SSF69572 (Activatin...)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MIA_05265_1
MTPSEKDIKFDRQLRLWGPVGQKSLENSHIALIGATPVGSELLKDLILPNIGKFTIIDGGNVTEEDISANFFVGSDSLGK
PRAQEVKELLNELNEDVIGNHINQDAESLLNYPVSFWQKFNVVIASSKNPSFLDQLSTILFPLNIPLVILESMSFYAYML
IIVKEHTIIETHPVSLVDLRLNKPWPALLSFVDQYDLDSLDDVDLAHVPYIVLLLKFLKSWKESHSGLPPTKRELKEFKA
MILSYRKSTDHVNFDEAIAAAGHLFAPCTIPDNLQIILNDPKTNLDFNSSNFWILVSSLKDFIELPQSGGCLPLTGVLPD
MTADTECYIRMQEIYREKAKADIDLFTKILHSNLTKINRSIDSIATQEIEVFCKNSKNIKVIRGSSLEEIHNFPKTIENL
GMEHEQFHVFLAIETSKYFLEQQQRYLGRSNAIEEDIETAKKIAKEVSANYGVNEIYPDTIKIIEEIARAGSYELHNLAA
LMGGIGSQEVVKLLTHQYSLLDNLVAFDGVMSKLQTWKL

GO term prediction

Biological Process

GO:0045116 protein neddylation

Molecular Function

GO:0008641 small protein activating enzyme activity
GO:0019781 NEDD8 activating enzyme activity

Cellular Component

None predicted.