Protein

MCA_03809_1

Length
535 amino acids

Browser: contigC:1148042-1149843-

RNA-seq: read pairs 2114, FPKM 48.7, percentile rank 64.9% (100% = highest expression)

Protein function

KEGG:K04532NAE1 amyloid beta precursor protein binding protein 1
EGGNOG:0PH8HFG04268.1NEDD8-activating enzyme E1 regulatory subunit
SGD closest match:S000005924ULA1NEDD8-activating enzyme E1 regulatory subunit
CGD closest match:CAL0000191482orf19.4153NEDD8-activating enzyme E1 regulatory subunit

Protein alignments

%idAln lengthE-value
MIA_05265_154.37%5260.0MIA_05265_1
A0A0J9X6A5_GEOCN47.90%5474e-156NEDD8-activating enzyme E1 regulatory subunit OS=Geotrichum candidum GN=BN980_GECA04s02474g PE=3 SV=1
UniRef50_A0A0J9X6A547.90%5477e-153NEDD8-activating enzyme E1 regulatory subunit n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6A5_GEOCN
A0A060SZD4_BLAAD42.48%5321e-135NEDD8-activating enzyme E1 regulatory subunit OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C06622g PE=3 SV=1
A0A1E3PIK5_9ASCO40.98%5325e-126NEDD8-activating enzyme E1 regulatory subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83652 PE=3 SV=1
A0A1D8PN68_CANAL39.05%5487e-111NEDD8-activating enzyme E1 regulatory subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.4153 PE=3 SV=1
Q6C046_YARLI38.42%5311e-107NEDD8-activating enzyme E1 regulatory subunit OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F27863g PE=3 SV=1
A0A167EIS0_9ASCO38.53%5455e-106NEDD8-activating enzyme E1 regulatory subunit OS=Sugiyamaella lignohabitans GN=ULA1 PE=3 SV=1
A0A1E4TB78_9ASCO32.63%5185e-73NEDD8-activating enzyme E1 regulatory subunit OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3631 PE=3 SV=1
ULA1_YEAST25.19%5281e-39NEDD8-activating enzyme E1 regulatory subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ULA1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1271

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 535

Detailed signature matches

  1. Family IPR030667
    NEDD8-activating enzyme E1 regulatory subunit APP-BP1
    1. PIRSF039099 (APP-BP1)
  2. Domain IPR000594
    THIF-type NAD/FAD binding fold
    1. PF00899 (ThiF)
    2. SSF69572 (Activatin...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...

Protein sequence

>MCA_03809_1
MSSAPSEKDRKFDRQLRLWGTLGQTYLEESHVALIGATPLGSEMLKNLILPNIGSFTIIDDSNITESDTSSNFFVESDSI
GKPKAPMVQSLLNELNEDVKGNYIQKSLESILESESDSFWTKFTVVIASNVKTSLLLKLSKILFTLNIPLVIAETKSFFG
SLYISNPEHTIIETHPTSLVDLRLDDPWPELVEFSNQYHLDELDDTDLSHVPYIVILLKYLETWKANHSGQLPKSSKEKR
EFKALIRADSHNGDFGNFEEAEKNTFALFSDSSVPNEIEEILNDKKADMSTYLTKDSSKPIPEFWILVSALKDFVSLPES
KHKLPVTGVLPDMTADTKGFVSMQKVYKNKATEDVKIFTDLLHKKLQEVNLPVDTISSDIIETFCKNSRHIQVIHGTSFD
KYWSSPEPVDLSSSDHTEFSVFLGIQIAKLFEERHDHPLGRTEDLEKDLESAKTISEEVCSKFKLDQVPQSVSDIVAEIA
RAGSYEFHNLSSFMGGIGGQEVIKIITHQYPPLDNLMAFDGIQSKSQSWKTRVLE

GO term prediction

Biological Process

GO:0045116 protein neddylation

Molecular Function

GO:0008641 small protein activating enzyme activity
GO:0019781 NEDD8 activating enzyme activity

Cellular Component

None predicted.