Protein

MIA_05255_1

Length
984 amino acids


Browser: contig07:1138521-1141633+

Protein function

EGGNOG:0PGFUISM1Isoleucyl-tRNA synthetase
SGD closest match:S000005961ISM1Isoleucine--tRNA ligase, mitochondrial
CGD closest match:CAL0000185259CAALFM_CR03400WAIsoleucine--tRNA ligase

Protein alignments

%idAln lengthE-value
MCA_04721_165.99%9850.0MCA_04721_1
A0A0J9X6B1_GEOCN65.78%9760.0Similar to Saccharomyces cerevisiae YPL040C ISM1 Mitochondrial isoleucyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA03s06104g PE=3 SV=1
UniRef50_A0A0J9X6B165.78%9760.0Similar to Saccharomyces cerevisiae YPL040C ISM1 Mitochondrial isoleucyl-tRNA synthetase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6B1_GEOCN
Q6CCB9_YARLI48.84%9930.0YALI0C10780p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C10780g PE=3 SV=1
A0A1E3PK96_9ASCO48.24%10220.0Isoleucyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51139 PE=3 SV=1
A0A060TE49_BLAAD46.00%9740.0ARAD1D49060p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D49060g PE=3 SV=1
A0A1E4TL64_9ASCO44.85%9410.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56159 PE=3 SV=1
A0A1D8PSG5_CANAL43.36%9710.0Isoleucine--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR03400WA PE=3 SV=1
SYIM_YEAST41.76%10130.0Isoleucine--tRNA ligase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ISM1 PE=1 SV=2
A0A167EHT4_9ASCO46.80%5942e-168Isoleucine--tRNA ligase ISM1 OS=Sugiyamaella lignohabitans GN=ISM1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5285

Protein family membership

Domains and repeats

Detailed signature matches

    1. PR00984 (TRNASYNTHILE)
    1. MF_02002 (Ile_tRNA_...)
    1. PF00133 (tRNA-synt_1)
    1. SSF50677 (ValRS/Ile...)
    1. SSF47323 (Anticodon...)
    1. PF08264 (Anticodon_1)
    1. cd07960 (Anticodon_...)
    1. PS00178 (AA_TRNA_LI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52374 (Nucleotid...)

Residue annotation

  1. tRNA binding surfa...
  2. anticodon binding ...

Protein sequence

>MIA_05255_1
MLRLKVVTKQPNPYLIKLYSTISKSKDLNHSYADTLSLPKTEFPNRSGKPDAIAKLIKRSSDEVYDWQINSNSFKKTSVF
HDGPPYANASLHLGHAMNKILKDIINRYDLLQGKKVFYRPGWDCHGLPIELKALQTLSAEAKKDVATVLSPTEIRTIAKS
HALEAIEDQMNSFRKFGVMGDWAHRYRTLDTDYEIRQLNVFKEMMHRGFISRKNKPVYWGTETRTALAEAELEYNEKHKS
TAATVKFPIVTLGENLKKIIGEKIPSSEKLNVLIWTTTPWTLISNKAVAVNAEMEYVVVSHETHGLFIVAESRRQSLGED
FKKIDGISFTGTDLLSSTYKSPLSNDSEERPFLAATYVTSTIGTGLVHTAPGHGFDDYLLCRKHNIDTYSPVDDEGKYTN
LPDEFKHLEGMYVLNQGQKEVIKILEENGSIISLNRNYRHKYPYDWRSKKPVIIRSTPQWFADIDSIKEDAVKALQDVIF
YPSTGKTRLEAFTQSRSEWCISRQRVWGVPIPAIYNKQTLEPLTDNSSMDYVISQIEKLGTDAWFEEEEDVQKWLPNTPE
FESKGKDYVKGKDTMDVWFDSGTSWTMLDPSHGEYLADYYLEGTDQHRGWFQSSLLTKIAVSEKGNAKAPFKHIITHGFT
LDEKGQKMSKSLGNTIAPEKIINGQKGKWPPLGVDGLRLWVASSDYTKDVSVGPIVLKNVAESLKKLRITIRFLLGSLHD
YTEELKFDKENFHPIDLIALHQLKKMTEQVKEQYDVFCFNRVVQIINHHTNTYLSAFYFDIIKDRLYAAPHNSTERRAVQ
YVLSEILRVYLSILSPITPLLTQEALDYTSQIINKGQTSPFKLGWVELPQEYHDPVFEEEIPLIEKVLSVVKQAMEAGRV
AKDITSSLSCDINVYVEGSGKVVNIIEKYRKHLPELFICSQVEVNPELSISEGWKYSASSQIDGVKVTAEAVPTKHHKCP
RCWQFTSLIEDSLCKRCDETLSQA

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006428 isoleucyl-tRNA aminoacylation

Molecular Function

GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004822 isoleucine-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm