Protein

MIA_05227_1

Length
463 amino acids

Browser: contig07:1075769-1077161+

Protein function

EGGNOG:0PFSUPGUG_03368Pseudouridine synthase
SGD closest match:S000005236PUS4tRNA pseudouridine synthase 4
CGD closest match:CAL0000191725PUS4Pseudouridine synthase

Protein alignments

%idAln lengthE-value
A0A0J9X6U9_GEOCN51.275%3533.95e-106Similar to Saccharomyces cerevisiae YNL292W PUS4 Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification OS=Geotrichum candidum GN=BN980_GECA04s04850g PE=3 SV=1
UniRef50_A0A0J9X6U951.275%3538.08e-103Similar to Saccharomyces cerevisiae YNL292W PUS4 Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6U9_GEOCN
MCA_04338_148.857%3503.31e-102MCA_04338_1
A0A167CLJ8_9ASCO36.132%3937.38e-68Pseudouridine synthase PUS4 OS=Sugiyamaella lignohabitans GN=PUS4 PE=3 SV=1
A0A060T396_BLAAD39.255%3494.03e-68ARAD1C38896p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38896g PE=3 SV=1
A0A1D8PN62_CANAL37.394%3534.29e-60Pseudouridine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PUS4 PE=3 SV=1
PUS4_YEAST35.884%3791.69e-59tRNA pseudouridine synthase 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PUS4 PE=1 SV=1
A0A1E3PP18_9ASCO35.398%3392.76e-58Pseudouridine synthase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_11695 PE=3 SV=1
A0A1E4TJ25_9ASCO42.857%2032.06e-41Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30105 PE=3 SV=1
Q6C7U6_YARLI33.668%1991.59e-25YALI0D25234p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D25234g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0824

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 463

Detailed signature matches

  1. Family IPR014780
    tRNA pseudouridine synthase II, TruB
    1. MF_01080 (TruB_bact)
  2. Domain IPR020103
    Pseudouridine synthase, catalytic domain
    1. SSF55120 (Pseudouri...)
  3. Domain IPR002501
    Pseudouridine synthase II, N-terminal
    1. PF01509 (TruB_N)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.23...
  3. mobidb-lite (disord...)

Protein sequence

>MIA_05227_1
MEGIFAISKPSGPSSAQAVSALKSALNASPYVENSSAWAKANGVKIKLTTDKRKKQWWYKKHDKNAAAIGGIKVGHGGTL
DPLASGVIVIGVGEGTKTLTKFLTDCTKVYEATAIFGAATTTYDSTGSTIQYSQDLASKLSPEALQQTIAAHFKGPISQY
PPVYSALKMDGKPLYEYARQAIPLPRKIEPRDSTVQFFDIVPGSFAFVAPDQIADLLPTKMATEDELAFYLRETMPPPTA
SLSDLAAAATPPPQFARVKFRFSVSSGTYIRSLIHDVATQMGLTAYMATLVRVQQGPFELGKNVFDLDDITKNLKDEEWV
PMVKLMLERGPDITIDHIKQLAQEDKEKKARDEVQDKEVQDKEVQDKEVQNKEVQDKEVQDKEVQDKEVQDKEVQNKETK
LDQKTTDLQTPTEPPSDTQKTPAQEPTNTAQLGFQETQNQEPDKHPRDSLDNQEPAPKKQKQE

GO term prediction

Biological Process

GO:0001522 pseudouridine synthesis
GO:0006396 RNA processing
GO:0009451 RNA modification

Molecular Function

GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity

Cellular Component

None predicted.