Protein

MIA_05219_1

Length
989 amino acids

Browser: contig07:1052583-1055682+

Protein function

EGGNOG:0PG83CREBubiquitin carboxyl-terminal hydrolase
SGD closest match:S000000163UBP13Ubiquitin carboxyl-terminal hydrolase 13
CGD closest match:CAL0000181088UBP13Ubiquitin-specific protease

Protein alignments

%idAln lengthE-value
MCA_05587_160.452%7080.0MCA_05587_1
A0A0J9X2T2_GEOCN56.831%6880.0Similar to Saccharomyces cerevisiae YDR069C DOA4 Ubiquitin isopeptidase OS=Geotrichum candidum GN=BN980_GECA01s05719g PE=3 SV=1
A0A060TDB7_BLAAD74.859%3540.0ARAD1B23408p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B23408g PE=3 SV=1
A0A161HN96_9ASCO68.159%4020.0Ubp13p OS=Sugiyamaella lignohabitans GN=UBP13 PE=3 SV=1
UniRef50_A0A161HN9668.159%4020.0Ubp13p n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A161HN96_9ASCO
A0A1E3PL69_9ASCO49.377%6420.0Cysteine proteinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46616 PE=3 SV=1
Q6C381_YARLI67.448%3842.14e-180YALI0F01903p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01903g PE=3 SV=1
A0A1E4TKW3_9ASCO66.667%3211.70e-156Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56067 PE=3 SV=1
A0A1D8PG89_CANAL46.903%3391.07e-94Ubiquitin-specific protease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UBP13 PE=3 SV=1
UBP13_YEAST46.894%3223.53e-90Ubiquitin carboxyl-terminal hydrolase 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBP13 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0356
Predicted cleavage: 34

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 989

Detailed signature matches

  1. Domain IPR028889
    Ubiquitin specific protease domain
    1. PS50235 (USP_3)
  2. Domain IPR001394
    Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    1. PF00443 (UCH)
  3. SITE IPR018200
    Ubiquitin specific protease, conserved site
    1. PS00972 (USP_1)
    2. PS00973 (USP_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.90.70.10
  3. SSF54001 (Cysteine ...)
  4. cd02663 (Peptidase_...)
  5. mobidb-lite (disord...)

Residue annotation

  1. Active Site cd02663

Protein sequence

>MIA_05219_1
MAPSIVAPQAQNALATPPPPQPPAPPLPALQRPPSASVEATSSAPSPAPTNSTAANDILADSANKIFGFENFGNTCYCNS
VLQCLYYSKPFREHVISFASDPAAAPHQRRTAVPGLKPHPFTVDPVAAAVATSNPTTATIAATAANMSHPTSATSHNNLS
SAPTTVTSNSHESNGKSQASLGRRLSIFGYNKDKDKQPASNTLKNIPEPLNGSSSSSSSKNTSNNIPTGSSSNLPSSISA
PNLALSHLSTQNGNHNDPQHQQPDSDHHIAEDEKEVDHSHLLNGNKATPLPNSVAFDTNGPTSYQNSKLLYPALRTIYLG
IRQSGQNIPVVGHTIDRSTTPEVRKRAALIKGPIINIDLSFADTYNMKESLFTSLKDIFECMAEVTSQIGIVSPAKLIQV
LKRENELFRTSMHQDAHEFLNFLLNEVIDCIDRQNRLPPHLGSSATGSPSSSSRWVHDLFEGLLTSETKCLTCETVSRRD
EQFLDLSIDIERNTSVTSCLRQFSASEMLCERNKFNCDHCGGFHEAQKRMKIKKLPKILALHLKRFKYTEDLQRNVKLFH
RVVYPQYLRLFNTTDDAQDSEKLYELYAVVVHIGGGPYHGHYVSVVKTENAGWLLFDDEMVDAVDPNYVFNFFGDNKSLA
TAYVLFYQEISQETYERDNLYSNVNIVRPTRVPNVSVPANNNHSNKNQNNVNSPTHPYAPGNGSPVVSPTPIAASTMTTL
NSQVEALEKSAQDDEQNGEPIFANGIKTEGTANPHTVSSTQTQAPISTSAPPPPPSRSVSPKRRPMSAFFTKRTVAPIVT
NTTSLPQQQVSPAGSQPNKSLSPFADTSEEVGFEQDVEKTLPAGQKKLQNSASQSQQFRMSMSSPPPSIPDYSTKPIIKT
KPTPIQGNGSSTQQQVSSPSSSSSSSSSTAAAVAAAASAAPAAATPAPSHSYGLSRFKSTRRSISGAASKENGSNGQADR
YNNLGNGDGTPLSAAKRKTRHLSFGFKKH

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination

Molecular Function

GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component

None predicted.