Protein

MCA_05587_1

Length
955 amino acids

Browser: contigD:1729304-1732172+

RNA-seq: read pairs 1546, FPKM 20.0, percentile rank 41.4% (100% = highest expression)

Protein function

KEGG:K11872UBP9_13 ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
EGGNOG:0PG83CREBubiquitin carboxyl-terminal hydrolase
SGD closest match:S000000163UBP13Ubiquitin carboxyl-terminal hydrolase 13
CGD closest match:CAL0000181088UBP13Ubiquitin-specific protease

Protein alignments

%idAln lengthE-value
MIA_05219_160.31%7030.0MIA_05219_1
A0A0J9X2T2_GEOCN73.60%4470.0Similar to Saccharomyces cerevisiae YDR069C DOA4 Ubiquitin isopeptidase OS=Geotrichum candidum GN=BN980_GECA01s05719g PE=3 SV=1
A0A161HN96_9ASCO69.72%4260.0Ubp13p OS=Sugiyamaella lignohabitans GN=UBP13 PE=3 SV=1
UniRef50_A0A161HN9669.72%4260.0Ubp13p n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A161HN96_9ASCO
A0A060TDB7_BLAAD76.92%3640.0ARAD1B23408p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B23408g PE=3 SV=1
Q6C381_YARLI70.26%3900.0YALI0F01903p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F01903g PE=3 SV=1
A0A1E3PL69_9ASCO64.08%3736e-170Cysteine proteinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46616 PE=3 SV=1
A0A1E4TKW3_9ASCO61.86%3541e-154Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_56067 PE=3 SV=1
A0A1D8PG89_CANAL47.14%3672e-98Ubiquitin-specific protease OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=UBP13 PE=3 SV=1
UBP13_YEAST46.06%3308e-90Ubiquitin carboxyl-terminal hydrolase 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=UBP13 PE=1 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1016

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 955

Detailed signature matches

  1. Domain IPR028889
    Ubiquitin specific protease domain
    1. PS50235 (USP_3)
  2. Domain IPR001394
    Peptidase C19, ubiquitin carboxyl-terminal hydrolase
    1. PF00443 (UCH)
  3. SITE IPR018200
    Ubiquitin specific protease, conserved site
    1. PS00972 (USP_1)
    2. PS00973 (USP_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.90.70.10
  2. SSF54001 (Cysteine ...)
  3. cd02663 (Peptidase_...)
  4. mobidb-lite (disord...)

Residue annotation

  1. Active Site cd02663

Protein sequence

>MCA_05587_1
MASSPEFTTFRSSNPTASDHLKQNSTSFPPTSNTSSSSSLPYDILTESANKIFGFENFGNTCYCNSVLQCLYYSKPFREQ
VLNFASEYKTSTKRRTTVPGSSPHSFTVDYHNNASSQIPSSSSSSFSHANNGNPAQASTPIAAALASAQAQQEARQRAAQ
LNGNSTQDHSSEPKKNQSSLGRKLSIFGGNKNKDSHSEKNDTSISEDSSANGTNNNNNNNNNNNNNNNNNNNNNNNSSTA
SSNDNLNDHSNQNGNNSASQDLSESNPNNHVHHEEHEHYNDNNHLAISSLFESNSPTSYAISKYLYPGLQGIMLGIRIPG
QNIPIVGYTDDPFATQEMRKRAALVKGPIVNMDQSFSDNYSMKESLFTSLKDIFECMAESSSRIGVVSPVKLIQVLKREN
ELFRSSMHQDAHEFLNFLLNEVIENVDRQNRLIGSKANGNKTNNDAALTPSSKSRWVHDLFEGLLTSETKCLTCETVSRR
DEQFLDLSIDIERNTSVTACLRQFSASETLCERNKFNCDNCGGFHEAQKRMKVKKLPKILALHLKRFKYTEDLQRNVKLF
HRVVYPRYLRLFDTTHDAQDPDKLYELYAVVVHIGGGPYHGHYVSIVKTEHAGWLLFDDEMVEAVDPNYVFNFFGDNKSL
ATAYVLFYQEVSPEQYEHENLYANNNLSNSFHSPVTVNGNGHGFNAGVGPYGSSSVISPTPLAASTVTTLSTQVEDLEQS
TPFANNSTTNTTTEQALHQQDSQPYQPVKTPTSLDDHSNNLLTRKRSHLIPFSHSKRLQNSNNENRSSFEGQNNSTDPPA
NTDEDNFNRNETLNSHKATTSKASPQMVPVTKQTSLHGLSRFKSGTLSRRSLSLGQNNFTTPNLPLQSPTTTTTTTTTTS
NNDNNGGSFWKRGNSHHNHENEPLEESKKVDHAENQRPITPTTPTTPTTASLSNGNGAPLSKRKSRHLSFTFKKK

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination

Molecular Function

GO:0036459 thiol-dependent ubiquitinyl hydrolase activity

Cellular Component

None predicted.