Protein

MIA_05209_1

Length
639 amino acids

Browser: contig07:1030070-1031990+

Protein function

EGGNOG:0PJ61FG00621.1Dna polymerase
SGD closest match:S000000607POL4DNA polymerase IV

Protein alignments

%idAln lengthE-value
MCA_05987_131.873%4116.36e-60MCA_05987_1
UniRef50_A0A1E3QZQ529.231%3904.40e-44Uncharacterized protein n=1 Tax=Babjeviella inositovora NRRL Y-12698 TaxID=984486 RepID=A0A1E3QZQ5_9ASCO
Q6C9C2_YARLI35.776%2321.05e-43YALI0D12364p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D12364g PE=4 SV=1
A0A167E5M8_9ASCO40.090%2221.53e-43Pol4p OS=Sugiyamaella lignohabitans GN=POL4 PE=4 SV=1
A0A1E4TL72_9ASCO27.720%3862.97e-42Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1110 PE=4 SV=1
A0A0J9X859_GEOCN27.460%4371.82e-41Similar to Saccharomyces cerevisiae YCR014C POL4 DNA polymerase IV OS=Geotrichum candidum GN=BN980_GECA05s00120g PE=4 SV=1
A0A060T9I9_BLAAD36.486%2225.66e-40ARAD1D15576p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D15576g PE=4 SV=1
A0A1E3PG04_9ASCO34.247%2191.48e-35Nucleotidyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71380 PE=4 SV=1
DPO4_YEAST22.807%2281.38e-13DNA polymerase IV OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POL4 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5711
Predicted cleavage: 26

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 639

Detailed signature matches

  1. Family IPR022312
    DNA polymerase family X
    1. PR00869 (DNAPOLX)
  2. Family IPR002008
    DNA polymerase family X, beta-like
    1. PR00870 (DNAPOLXBETA)
  3. Domain IPR001357
    BRCT domain
    1. SSF52113 (BRCT domain)
    2. cd00027 (BRCT)
    3. G3DSA:3.40.50...
    4. PS50172 (BRCT)
  4. Domain IPR010996
    DNA polymerase beta-like, N-terminal domain
    1. PF14716 (HHH_8)
    2. SSF47802 (DNA polym...)
  5. Domain IPR002054
    DNA-directed DNA polymerase X
    1. cd00141 (NT_POLXc)
    2. SM00483 (polxneu3)
  6. Domain IPR003583
    Helix-hairpin-helix DNA-binding motif, class 1
    1. SM00278 (HhH1_4)
  7. Domain IPR018944
    DNA polymerase lambda, fingers domain
    1. PF10391 (DNA_pol_la...)
  8. Domain IPR028207
    DNA polymerase beta, palm domain
    1. PF14792 (DNA_pol_B_...)
  9. Domain IPR029398
    DNA polymerase beta, thumb domain
    1. G3DSA:3.30.21...
    2. PF14791 (DNA_pol_B_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.15...
  2. G3DSA:1.10.15...
  3. G3DSA:3.30.46...
  4. NON_CYTOPLASM... (N...)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. SSF81301 (Nucleotid...)
  10. SSF81585 (PsbU/PolX...)
  11. mobidb-lite (disord...)

Residue annotation

  1. Dimer interface cd...
  2. BRCT sequence moti...
  3. primer binding sit...
  4. active site cd00141
  5. NTP binding site ...
  6. metal binding tria...

Protein sequence

>MIA_05209_1
MALFTDLAFYVFPARTSARAYKIRRKVYQTHGALVLETLDATTPRQATHIVVDSNWLAQPARLQGSGLAHLEEWASQHGN
VPIVHDMWALECVAQNKVLDVTPFLVGTEPTDSETESEDDKNNSPNQHVQRDLAGEEMKKEPSARSCSPPLEAEHPKPSP
MNESSNAAVLQGLERLKQHYDTLGDRWRAVGYARAIAAISREPAPVCTFEQAQALPGVGTSLARKIVELAAGRTVDPPSV
SALDAAAATKANKERAQLAKIHGVGPATARKWHAAGIHTPADVRARLWDTLTPAQRIGLAHLADFEARIPRAEAAQHWAI
VRDAVHAVDPHAEALCMGSFRRGCATCGDVDIVVTRAGASAQELRHVVARVLVNLFQSGYLVASLSGPVPGVDVPGEYDF
GDNEGGSCSSSTDQSDESDADDEEDAEGVSEFVDEYSAAAVASDPASMPPAKRLKLSPSRIADTSPPGTRAATPSPISRG
AMSPRQPHGPQQTSPASSRFSKPNLGATRYPNHRQKYRLPRLWMAAGKLPKGSPGLEPGSVPRWRRIDIIIVPWAERGAA
MLHYTGSELFNRNLRIVAMQHGYHLSNKGLYRAVIPHGTKRSGINVRSCVPEQLVEATDEYKIFEILGLPYRPPNERSK

GO term prediction

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0034061 DNA polymerase activity

Cellular Component

GO:0005634 nucleus