Protein

MCA_05987_1

Length
635 amino acids

Description: putative DNA polymerase

Browser: contigD:2966836-2968744-

RNA-seq: read pairs 457, FPKM 8.9, percentile rank 24.0% (100% = highest expression)

Protein function

Annotation:putative DNA polymerase
EGGNOG:0PJ61FG00621.1Dna polymerase
SGD closest match:S000000607POL4DNA polymerase IV

Protein alignments

%idAln lengthE-value
UniRef50_A0A1D2VPH729.33%6001e-69Nucleotidyltransferase n=1 Tax=Ascoidea rubescens DSM 1968 TaxID=1344418 RepID=A0A1D2VPH7_9ASCO
A0A167E5M8_9ASCO50.45%2227e-65Pol4p OS=Sugiyamaella lignohabitans GN=POL4 PE=4 SV=1
A0A060T9I9_BLAAD34.91%4441e-63ARAD1D15576p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D15576g PE=4 SV=1
Q6C9C2_YARLI45.22%2302e-60YALI0D12364p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D12364g PE=4 SV=1
A0A0J9X859_GEOCN33.41%4493e-61Similar to Saccharomyces cerevisiae YCR014C POL4 DNA polymerase IV OS=Geotrichum candidum GN=BN980_GECA05s00120g PE=4 SV=1
MIA_05209_132.77%4151e-60MIA_05209_1
A0A1E3PG04_9ASCO42.20%2189e-51Nucleotidyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_71380 PE=4 SV=1
A0A1E4TL72_9ASCO35.84%2264e-46Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1110 PE=4 SV=1
DPO4_YEAST27.19%2172e-15DNA polymerase IV OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POL4 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0324
Predicted cleavage: 15

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 635

Detailed signature matches

  1. Family IPR022312
    DNA polymerase family X
    1. PR00869 (DNAPOLX)
  2. Family IPR002008
    DNA polymerase family X, beta-like
    1. PR00870 (DNAPOLXBETA)
  3. Domain IPR001357
    BRCT domain
    1. SSF52113 (BRCT domain)
    2. G3DSA:3.40.50...
    3. PS50172 (BRCT)
  4. Domain IPR010996
    DNA polymerase beta-like, N-terminal domain
    1. PF14716 (HHH_8)
    2. SSF47802 (DNA polym...)
  5. Domain IPR002054
    DNA-directed DNA polymerase X
    1. cd00141 (NT_POLXc)
    2. SM00483 (polxneu3)
  6. Domain IPR018944
    DNA polymerase lambda, fingers domain
    1. PF10391 (DNA_pol_la...)
  7. Domain IPR028207
    DNA polymerase beta, palm domain
    1. PF14792 (DNA_pol_B_...)
  8. Domain IPR029398
    DNA polymerase beta, thumb domain
    1. G3DSA:3.30.21...
    2. PF14791 (DNA_pol_B_...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:1.10.15...
  2. G3DSA:1.10.15...
  3. G3DSA:3.30.46...
  4. SSF81301 (Nucleotid...)
  5. SSF81585 (PsbU/PolX...)
  6. mobidb-lite (disord...)

Residue annotation

  1. primer binding sit...
  2. active site cd00141
  3. NTP binding site ...
  4. metal binding tria...

Protein sequence

>MCA_05987_1
MKRRRQLSTKKSIEARKKVALKTDEQKEQSESSSSLDKLFSGLVFHLFPTNQKNKAYYIKRNAYEKAGATIIDSLPKSFG
SKVSTSPTHIIVKLGAEKTPAFESLKQALDLTQDKPGAPLVVNDAWPGECISSNKLLDCEPFLVNQPAKVEAPETAKECK
NSEDESVVEIQSDDFPKTQKKQQYEQIILSAPEKSGSNLKPFKDENASSKKDYTPPPLLDNNPNKEIIDIFSGVMHFHEL
QGKKFNALGYRRAISTLKRTMTPILTYKQAKELPGFGEKLARKVEEIVQTKGLKKLQALSNDESLKVRGMLEVIYGVGPT
TSLKWYNEGVRTLEDVAKRTDLTDQQRTSLSHYHDFAERIPRDEVTRHYEYVLKVLKEIDPESEAYCMGSYRRGRQTCGD
IDILITKKGVDSSKDLEVLLFKLICALFEKGFFTAAFSGPDARNYNCNVSEMIDAFHNRKKRVSKKNKKALEGQVQESEV
DSSNSSDESKSSEGSGSDSGVTKKRRRVLTQYFTKWLGASCLEDVGKWRRLDLLMVPWKEKGAALIYFTGNDSYNRSLRI
LAKSKGYHLNEKGLFRIPGFSHKSTFESQADVPLSALFDWRKKKYDVNDLVEGSDERKILEILGVPWTEPEDRDI

GO term prediction

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0034061 DNA polymerase activity

Cellular Component

GO:0005634 nucleus