Protein

MIA_05203_1

Length
499 amino acids

Browser: contig07:1015627-1017204+

Protein function

EGGNOG:0PIATNMT1Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity)
SGD closest match:S000004185NMT1Glycylpeptide N-tetradecanoyltransferase
CGD closest match:CAL0000201559NMT1Glycylpeptide N-tetradecanoyltransferase

Protein alignments

%idAln lengthE-value
MCA_00984_167.004%4940.0MCA_00984_1
A0A0J9X9Q5_GEOCN57.019%4630.0Glycylpeptide N-tetradecanoyltransferase OS=Geotrichum candidum GN=BN980_GECA06s02034g PE=3 SV=1
A0A167ECH6_9ASCO53.293%5012.54e-178Glycylpeptide N-tetradecanoyltransferase OS=Sugiyamaella lignohabitans GN=NMT1 PE=3 SV=1
A0A060T9G1_BLAAD55.202%4711.61e-169Glycylpeptide N-tetradecanoyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37730g PE=3 SV=1
NMT_CANAL48.620%4711.08e-152Glycylpeptide N-tetradecanoyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NMT1 PE=1 SV=2
NMT_YARLI50.881%4541.03e-150Glycylpeptide N-tetradecanoyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NMT1 PE=3 SV=1
A0A1E3PS15_9ASCO49.318%4402.68e-145Glycylpeptide N-tetradecanoyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_63678 PE=3 SV=1
UniRef50_A0A1X7R2H150.794%4415.14e-146Similar to Saccharomyces cerevisiae YLR195C NMT1 N-myristoyl transferase n=1 Tax=Kazachstania saulgeensis TaxID=1789683 RepID=A0A1X7R2H1_9SACH
NMT_YEAST48.292%4391.99e-137Glycylpeptide N-tetradecanoyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NMT1 PE=1 SV=1
A0A1E4TAV3_9ASCO46.789%4366.75e-129Glycylpeptide N-tetradecanoyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57947 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0371

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 499

Detailed signature matches

  1. Family IPR000903
    Myristoyl-CoA:protein N-myristoyltransferase
    1. PIRSF015892 (N-myri...)
  2. Domain IPR016181
    Acyl-CoA N-acyltransferase
    1. SSF55729 (Acyl-CoA ...)
  3. Domain IPR022676
    Myristoyl-CoA:protein N-myristoyltransferase, N-terminal
    1. PF01233 (NMT)
  4. Domain IPR022677
    Myristoyl-CoA:protein N-myristoyltransferase, C-terminal
    1. PF02799 (NMT_C)
  5. SITE IPR022678
    Myristoyl-CoA:protein N-myristoyltransferase, conserved site
    1. PS00975 (NMT_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.63...
  2. mobidb-lite (disord...)

Protein sequence

>MIA_05203_1
MSDQPKETPSKSTDDSKLPPEEVAKRIGELPSKSGKAPALQGLSLENLFKLLAMANATPDPEEKNKPKPMDEYKFWKTQP
VVKFGEEKAEQEGPIDEEKTVDDVAKAPRKLLPNFEWCVIDLNDKKQIEELYSLLYNNYIEDDDNTFRFQYSPEFLEWAL
KPPGWRSEWNVGVRIKDTGKLIASITGIPQFLRVRDKPAQEMAEINFLCVHKKLRNKRLSPALIQEVTRKVNLENIWQAL
YTAGTILPSPLSVTRYYHRPLNWTKLYEVGFSAPLPNQTPAEMVARYALPGETTLKNLREMTREDIPQVFVLLHEYLKRF
DLAPEFQSEAELAHWLLGPEDPLFPVETREKKPVHSFVVTEDDGKTVTDFFSFYSIPTTVLGVPGHDNINIAYSFYYATS
VARDVPSTDRTLENQKPLVSRLKKLQQNALILSKQLGHDVYNAVTCMDNPLFFEDLKFSIGTGILNYYLFNYRAYPVHGG
MRKQFLEAPANGGVGTIML

GO term prediction

Biological Process

GO:0006499 N-terminal protein myristoylation

Molecular Function

GO:0004379 glycylpeptide N-tetradecanoyltransferase activity

Cellular Component

None predicted.