Protein

MCA_00984_1

Length
493 amino acids

Gene name: NMT1

Description: Glycylpeptide N-tetradecanoyltransferase

Browser: contigA:3129942-3131503-

RNA-seq: read pairs 2827, FPKM 70.7, percentile rank 72.9% (100% = highest expression)

Protein function

Annotation:NMT1Glycylpeptide N-tetradecanoyltransferase
KEGG:K00671NMT glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97]
EGGNOG:0PIATNMT1Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity)
SGD closest match:S000004185NMT1Glycylpeptide N-tetradecanoyltransferase
CGD closest match:CAL0000201559NMT1Glycylpeptide N-tetradecanoyltransferase

Protein alignments

%idAln lengthE-value
MIA_05203_167.91%4830.0MIA_05203_1
A0A0J9X9Q5_GEOCN57.85%4650.0Glycylpeptide N-tetradecanoyltransferase OS=Geotrichum candidum GN=BN980_GECA06s02034g PE=3 SV=1
A0A167ECH6_9ASCO52.71%4613e-175Glycylpeptide N-tetradecanoyltransferase OS=Sugiyamaella lignohabitans GN=NMT1 PE=3 SV=1
A0A060T9G1_BLAAD54.57%4601e-169Glycylpeptide N-tetradecanoyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37730g PE=3 SV=1
A0A1E3PS15_9ASCO49.66%4352e-148Glycylpeptide N-tetradecanoyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_63678 PE=3 SV=1
UniRef50_A0A1E3PS1549.66%4355e-145Glycylpeptide N-tetradecanoyltransferase n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PS15_9ASCO
NMT_CANAL47.51%4824e-148Glycylpeptide N-tetradecanoyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NMT1 PE=1 SV=2
NMT_YEAST50.56%4435e-147Glycylpeptide N-tetradecanoyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NMT1 PE=1 SV=1
NMT_YARLI47.84%4629e-141Glycylpeptide N-tetradecanoyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=NMT1 PE=3 SV=1
A0A1E4TAV3_9ASCO47.82%4351e-130Glycylpeptide N-tetradecanoyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57947 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0225

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 493

Detailed signature matches

  1. Family IPR000903
    Myristoyl-CoA:protein N-myristoyltransferase
    1. PIRSF015892 (N-myri...)
  2. Domain IPR016181
    Acyl-CoA N-acyltransferase
    1. SSF55729 (Acyl-CoA ...)
  3. Domain IPR022676
    Myristoyl-CoA:protein N-myristoyltransferase, N-terminal
    1. PF01233 (NMT)
  4. Domain IPR022677
    Myristoyl-CoA:protein N-myristoyltransferase, C-terminal
    1. PF02799 (NMT_C)
  5. SITE IPR022678
    Myristoyl-CoA:protein N-myristoyltransferase, conserved site
    1. PS00975 (NMT_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.63...
  2. mobidb-lite (disord...)

Protein sequence

>MCA_00984_1
MADKTPKDDNNDKPLSKDEIAQRIGELPSKSNNKLKGTDISKLLAMLSLANAAPTEEEKMTPKPMDEYKFWKTQPVPRFD
EDKVLKEGPIDSSKTVDDVPKTPGKLLPAFEWCVIDANDKKQLEEFYDLLYKNYIEDDDNTFRFRYTPQFLEWALKPPGW
KKEWNIGVRAKETGKLVASITGVPQVLRIKDMPPQLMGEVNFLCIHKKLRSKRLAPVLIKEVTRKINSDNIWQALYTAGL
ILPSPVATTRYYHRPLNWMKLNSVGFSASLPGQTPAQMVAKYALPKKPTLNNLRKMTMEDVPQVKELLNKYLDRFDMAPV
FETEDIAHWFIGSQNPLFEVSEEEKPVHSYVVTEDDGKTVTDFFSFYSIPTSVLGNSEYDSLNIAYSYYYASNVAFSVPS
KDRTPENQKKLAARLVVLQQNALIIAKNLNYDVYNAVTALDNPMFLSELKYSTGTGILNYYLFNYRVYSIDGGINKSQIL
TPPTNGGVGTILL

GO term prediction

Biological Process

GO:0006499 N-terminal protein myristoylation

Molecular Function

GO:0004379 glycylpeptide N-tetradecanoyltransferase activity

Cellular Component

None predicted.