Protein

MIA_05199_1

Length
697 amino acids


Browser: contig07:993468-995622-

Protein function

EGGNOG:0PHSNFG01789.1Ferric-chelate reductase
SGD closest match:S000005908FRE3Ferric reductase transmembrane component 3
CGD closest match:CAL0000193490CFL1Ferric/cupric reductase transmembrane component 1

Protein alignments

%idAln lengthE-value
MCA_05580_144.44%7110.0MCA_05580_1
A0A0J9XL84_GEOCN38.91%6811e-147Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p OS=Geotrichum candidum GN=BN980_GECA32s00846g PE=4 SV=1
UniRef50_A0A0J9XI2538.84%6903e-142Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI25_GEOCN
Q6CET4_YARLI36.57%6071e-101YALI0B13134p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B13134g PE=4 SV=1
A0A060SVU5_BLAAD36.69%5261e-94ARAD1A00286p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A00286g PE=4 SV=1
A0A167FY66_9ASCO31.57%7002e-92Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1
A0A1E3PIN1_9ASCO30.44%7036e-82Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83263 PE=4 SV=1
FRE1_CANAL32.69%5202e-80Ferric/cupric reductase transmembrane component 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFL1 PE=2 SV=2
A0A1E4TLJ4_9ASCO29.71%6162e-66Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30726 PE=4 SV=1
FRE3_YEAST29.73%5185e-63Ferric reductase transmembrane component 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE3 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7633
Predicted cleavage: 54

Protein family membership

None predicted.

Domains and repeats

1 100 200 300 400 500 600 697

Detailed signature matches

    1. PF01794 (Ferric_reduct)
    1. PS51384 (FAD_FR)
    1. PF08022 (FAD_binding_8)
    1. PF08030 (NAD_binding_6)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SFLDG01168 (Ferric_...)
  2. SFLDS00052 (Ferric_...)
  3. SSF52343 (Ferredoxi...)
  4. TRANSMEMBRANE (Tran...)
  5. cd06186 (NOX_Duox_l...)

Residue annotation

  1. FAD binding pocket...
  2. FAD binding motif ...
  3. NAD pyrophosphate ...
  4. NADP ribose bindin...
  5. NAD binding pocket...

Protein sequence

>MIA_05199_1
MKLLLQLTLLYISLSSVVATNSGDALFRGCAAWVSKYKFECPSKYAKSKGGRVTPCNCWSPEFIATYVDCAFRAKGANTN
YGLHSLLSTCATKTVRPDLTLDEINQIYLNASDYFVDVKTIKNKTETSYSPIRFTQAQIDQAQRSFAAGFYAKYTGQLYG
GLLLAYFGAILLAAAISNLLKKIAPGFVHKSTNNKVALFFRRKLINPALFGNKHSVPVKWGPFNMSLPTRAQFWVLAGYF
AMYIIFIFIKYDIYDGNTRFATRALQISRYVGDRAAIMALAQLPLVYTFAGRNNILIFLTGLSYDTMNLYHRWVSRVMYM
NIFIHAVCFSINYRKQGKYFSELKESDIVWGIVSCVCGGLAMFFSLRHFREKIYEIFLLTHWALVIFFTVGAWYHVKPHG
YMEWIYTAIAIWAFDRFGRLVRIVVNGINAKAHLELHPQHLIKIKVDYNSFWHPRAGAYAFIHFLNPLWRCWENHPFTLY
PSPIPGEEKKLIFCARVRSGKTAQIAKYLAANNNAKTVPIFIDGPYGHAVPLQTSESIVIITGGIGFTGGYSYACKLTHQ
AEKKNITFIWAIQNHENVETFRDELEYLYKNDVNVFIYLSNEPDGLQRKITVEKHNSDPENLNEKDLSSGSTISFNTTFQ
RPDLKVIIESAIADAPGSIGFLVCGPGSMNDDVRRNVSNNMGNGKARVDLYIEAFNW

GO term prediction

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.