Protein
MCA_05580_1
Length
716 amino acids
Gene name: FRE2A
Description: Ferric/cupric reductase transmembrane component 2
Browser: contigD:1698714-1700865-
RNA-seq: read pairs 463, FPKM 8.0, percentile rank 22.3% (100% = highest expression)
Protein function
Annotation: | FRE2A | Ferric/cupric reductase transmembrane component 2 | |
---|---|---|---|
EGGNOG: | 0PHSN | FG01789.1 | Ferric-chelate reductase |
SGD closest match: | S000001703 | FRE2 | Ferric/cupric reductase transmembrane component 2 |
CGD closest match: | CAL0000185898 | CFL4 | Ferric/cupric-chelate reductase |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_05670_1 | 45.20% | 708 | 0.0 | MIA_05670_1 |
A0A0J9XI25_GEOCN | 34.69% | 712 | 9e-141 | Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p OS=Geotrichum candidum GN=BN980_GECA16s00164g PE=4 SV=1 |
UniRef50_A0A0J9XI25 | 34.69% | 712 | 2e-137 | Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI25_GEOCN |
Q6CF26_YARLI | 33.93% | 669 | 5e-118 | YALI0B10846p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10846g PE=4 SV=1 |
A0A1E3PIN1_9ASCO | 31.31% | 677 | 2e-99 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83263 PE=4 SV=1 |
A0A060SVU5_BLAAD | 33.57% | 566 | 9e-100 | ARAD1A00286p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A00286g PE=4 SV=1 |
A0A167FY66_9ASCO | 29.81% | 681 | 5e-92 | Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1 |
A0A1D8PN54_CANAL | 29.78% | 675 | 8e-86 | Ferric/cupric-chelate reductase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFL4 PE=4 SV=1 |
A0A1E4TLJ4_9ASCO | 28.69% | 596 | 3e-71 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30726 PE=4 SV=1 |
FRE2_YEAST | 29.62% | 638 | 2e-66 | Ferric/cupric reductase transmembrane component 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7629
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
716
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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-
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NON_CYTOPLASM... (N...)
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SFLDG01168 (Ferric_...)
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SFLDS00052 (Ferric_...)
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SIGNAL_PEPTIDE (Sig...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SIGNAL_PEPTID... (S...)
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SSF52343 (Ferredoxi...)
-
-
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TRANSMEMBRANE (Tran...)
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cd06186 (NOX_Duox_l...)
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mobidb-lite (disord...)
Residue annotation
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FAD binding pocket...
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FAD binding motif ...
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beta-alpha-beta st...
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NAD pyrophosphate ...
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NAD binding pocket...
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NADP ribose bindin...
Protein sequence
>MCA_05580_1 MKISALLLLATANTALAIKSGDPVFRGCLRFYTPLTFQCPEEKAKGGAAKKPKKKSRVSKCNCQSPEFIASYTDCVLRSD GNHQKAFDSLLAACAIPGVNPDLTQEKVMEIYKNGTNYFIDYNTLPKEKSDGKDKKKNILYNPVKLPQEKVDVAVRGWRG FYYNWYVGQLYGGLLNAYFALIVFAAVVMNFCKRVFPKQVHAVSNIYIVKKFRQYIANPATCNQKHGVPGKWMKIINMSI PTRAQTIVIIGYWIIYLILNIIKYEVETSYFALVRMVGDRTGIIATAHLPLLFLFAGRNNILLYATNWSYDTMSCYHRWV AKGMYLGVFLHSVTFTVSYKNSGIYYSSFSKPDIVWGIVATVLGAFILFFSLRHFREYTYEFFLLSHQIFVVFFLIGTLY HVKPYGYAEWLWATIAVWAFDRAARLARIVISGLNSNAECQYYPESDVIKIKINYSEIWGASPGAYAFVYFLKPFWRCWE NHPFSLFPSPVPGEEKKLVLCVRAREGWTRYISKFLVKQPNYSMKCPILLEGPYGQHFHLQHNDNILLIAGGIGVTAVYS YVAKLRSQGQSKQITFVWLTRSIEYLNFFRDEIESLLQSDDIQVHIYVSQKSNINTPSTGSLSDEKRDSSTPSIDNSSSE EKCGESIISSKVMNCVSYGRPDLSEVIHNTVSDSAGTTGVMVCGPPGMNDDVRKFVTAEMGVSKNVIDLYVEGFNW
GO term prediction
Biological Process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
None predicted.