Protein

MIA_05190_1

Length
890 amino acids


Browser: contig07:963191-965965+

Protein function

EGGNOG:0PIVMCHL1Important for chromosome transmission and normal cell cycle progression in G(2) M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II (By similarity)
SGD closest match:S000005929CHL1ATP-dependent DNA helicase CHL1
CGD closest match:CAL0000177726CHL1ATP-dependent DNA helicase CHL1

Protein alignments

%idAln lengthE-value
A0A0J9XED3_GEOCN51.176%8930.0Similar to Saccharomyces cerevisiae YPL008W CHL1 Probable DNA helicase involved in sister-chromatid cohesion and genome integrity OS=Geotrichum candidum GN=BN980_GECA12s00142g PE=4 SV=1
UniRef50_A0A0J9XED351.176%8930.0Similar to Saccharomyces cerevisiae YPL008W CHL1 Probable DNA helicase involved in sister-chromatid cohesion and genome integrity n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XED3_GEOCN
MCA_06266_149.286%9110.0MCA_06266_1
A0A1E3PRD8_9ASCO43.569%8630.0ATP-dependent RNA helicase CHL1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81974 PE=4 SV=1
CHL1_YARLI43.216%8770.0ATP-dependent DNA helicase CHL1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CHL1 PE=3 SV=1
A0A167ENN5_9ASCO41.686%8420.0Chl1p OS=Sugiyamaella lignohabitans GN=CHL1 PE=4 SV=1
A0A060TDE4_BLAAD42.222%8100.0ARAD1B24046p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B24046g PE=4 SV=1
CHL1_CANAL40.114%8800.0ATP-dependent DNA helicase CHL1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CHL1 PE=3 SV=1
CHL1_YEAST36.080%8981.18e-178ATP-dependent DNA helicase CHL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CHL1 PE=1 SV=1
A0A1E4TGL2_9ASCO36.301%8652.58e-164Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11308 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0045

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 890

Detailed signature matches

    1. PS51193 (HELICASE_A...)
    1. SM00488 (deadxpd)
    1. PF06733 (DEAD_2)
    1. PF13307 (Helicase_C_2)
    2. SM00491 (Cxpdneu3)
    1. PS00690 (DEAH_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_05190_1
MPEHIDIDYETEKSPETFGHPYKPYDIQLQFMKELYDTLQHKKVGIFESPTGMFCSEGKTLSLICGSVSWLRDTRRNQFE
TTGEDKEDEATKKLPAWVREQSKQMKQNAIVEQLKDLEAALKEAISLEETELREAQSLKRKRPPADYTVKRQKPAKDDLD
SDFYVLQDQDESLDDDFLTQQEKELQAIKARTNALLQVLEEGPSTKDDQPVFGKDQPKIFFASRTHSQLSQFVGQLRLPT
FKSSVPAFMPDEPIKEISLASRRQLCIHPAVSKYKSTQKMNDACLDMQKESCGCEYMLNMRDIKSRVRYREFRNAALAKI
RDIEDLAQLGKTKRMCPYYATREIANNGWAEIIALPYQLLLQREARDALGINLTNSVVVIDEAHNLLDTISSLYSLELTY
SQISRALTGLQTYQKKFQSRLSGINRIWLAKLIKTVTSIAHFLKKAQRKPPQETGPGKNIPASSFFANDDGAADTINVHD
LEQFVKKTKLVFKIESYLDKLETLEQQQHHHLVLGKVISFLLAIGNPSWEGKFFYGRNANKELQVQYILLDPSVKFREIV
DECRCVILAGGTMKPTEDYLTYLFPYLAKDQISIFSCNHIIPDKNLTVLPVGQRQGIKFNFTFGERNSKPMIEQLGLALI
DICKTVPDGVVVFLPSYVYMNSVIKIWESSTTNNRTILGALKAVKSVFWEPQNSGTDSSYMPSVETAGATTKILEEYTKK
IEGTTGRGAVLFAVVGGKMSEGINFSDKLARAVVMVGLPFPHAFSAEMVAKRDYVEQTTIKQQLQKNGAKDGDNPIKSTS
VSSSLQQLGKAKAREYYENVCMRAVNQCVGRAIRHADDYAAVILLDNRYGTDHIQGKLSQWVQKRIVHGPNGGSLTDLDA
LSKLSAFFQR

GO term prediction

Biological Process

GO:0006139 nucleobase-containing compound metabolic process

Molecular Function

GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

Cellular Component

None predicted.