Protein
MIA_05190_1
Length
890 amino acids
Browser: contig07:963191-965965+
Protein function
| EGGNOG: | 0PIVM | CHL1 | Important for chromosome transmission and normal cell cycle progression in G(2) M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II (By similarity) |
|---|---|---|---|
| SGD closest match: | S000005929 | CHL1 | ATP-dependent DNA helicase CHL1 |
| CGD closest match: | CAL0000177726 | CHL1 | ATP-dependent DNA helicase CHL1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| A0A0J9XED3_GEOCN | 51.176% | 893 | 0.0 | Similar to Saccharomyces cerevisiae YPL008W CHL1 Probable DNA helicase involved in sister-chromatid cohesion and genome integrity OS=Geotrichum candidum GN=BN980_GECA12s00142g PE=4 SV=1 |
| UniRef50_A0A0J9XED3 | 51.176% | 893 | 0.0 | Similar to Saccharomyces cerevisiae YPL008W CHL1 Probable DNA helicase involved in sister-chromatid cohesion and genome integrity n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XED3_GEOCN |
| MCA_06266_1 | 49.286% | 911 | 0.0 | MCA_06266_1 |
| A0A1E3PRD8_9ASCO | 43.569% | 863 | 0.0 | ATP-dependent RNA helicase CHL1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81974 PE=4 SV=1 |
| CHL1_YARLI | 43.216% | 877 | 0.0 | ATP-dependent DNA helicase CHL1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CHL1 PE=3 SV=1 |
| A0A167ENN5_9ASCO | 41.686% | 842 | 0.0 | Chl1p OS=Sugiyamaella lignohabitans GN=CHL1 PE=4 SV=1 |
| A0A060TDE4_BLAAD | 42.222% | 810 | 0.0 | ARAD1B24046p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B24046g PE=4 SV=1 |
| CHL1_CANAL | 40.114% | 880 | 0.0 | ATP-dependent DNA helicase CHL1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CHL1 PE=3 SV=1 |
| CHL1_YEAST | 36.080% | 898 | 1.18e-178 | ATP-dependent DNA helicase CHL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CHL1 PE=1 SV=1 |
| A0A1E4TGL2_9ASCO | 36.301% | 865 | 2.58e-164 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11308 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0045
Protein family membership
- DNA helicase (DNA repair), Rad3 type (IPR013020)
Domains and repeats
-
Domain
-
Domain
-
Domain
1
100
200
300
400
500
600
700
800
890
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
mobidb-lite (disord...)
Protein sequence
>MIA_05190_1 MPEHIDIDYETEKSPETFGHPYKPYDIQLQFMKELYDTLQHKKVGIFESPTGMFCSEGKTLSLICGSVSWLRDTRRNQFE TTGEDKEDEATKKLPAWVREQSKQMKQNAIVEQLKDLEAALKEAISLEETELREAQSLKRKRPPADYTVKRQKPAKDDLD SDFYVLQDQDESLDDDFLTQQEKELQAIKARTNALLQVLEEGPSTKDDQPVFGKDQPKIFFASRTHSQLSQFVGQLRLPT FKSSVPAFMPDEPIKEISLASRRQLCIHPAVSKYKSTQKMNDACLDMQKESCGCEYMLNMRDIKSRVRYREFRNAALAKI RDIEDLAQLGKTKRMCPYYATREIANNGWAEIIALPYQLLLQREARDALGINLTNSVVVIDEAHNLLDTISSLYSLELTY SQISRALTGLQTYQKKFQSRLSGINRIWLAKLIKTVTSIAHFLKKAQRKPPQETGPGKNIPASSFFANDDGAADTINVHD LEQFVKKTKLVFKIESYLDKLETLEQQQHHHLVLGKVISFLLAIGNPSWEGKFFYGRNANKELQVQYILLDPSVKFREIV DECRCVILAGGTMKPTEDYLTYLFPYLAKDQISIFSCNHIIPDKNLTVLPVGQRQGIKFNFTFGERNSKPMIEQLGLALI DICKTVPDGVVVFLPSYVYMNSVIKIWESSTTNNRTILGALKAVKSVFWEPQNSGTDSSYMPSVETAGATTKILEEYTKK IEGTTGRGAVLFAVVGGKMSEGINFSDKLARAVVMVGLPFPHAFSAEMVAKRDYVEQTTIKQQLQKNGAKDGDNPIKSTS VSSSLQQLGKAKAREYYENVCMRAVNQCVGRAIRHADDYAAVILLDNRYGTDHIQGKLSQWVQKRIVHGPNGGSLTDLDA LSKLSAFFQR
GO term prediction
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Cellular Component
None predicted.