MCA_06266_1
Gene name: CHL1
Description: ATP-dependent DNA helicase CHL1
Browser: contigD:3718403-3721106+
RNA-seq: read pairs 257, FPKM 3.5, percentile rank 14.8% (100% = highest expression)
Protein function
| Annotation: | CHL1 | ATP-dependent DNA helicase CHL1 | |
|---|---|---|---|
| KEGG: | K11273 | DDX11 | chromosome transmission fidelity protein 1 [EC:3.6.4.13] |
| EGGNOG: | 0PIVM | CHL1 | Important for chromosome transmission and normal cell cycle progression in G(2) M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II (By similarity) |
| SGD closest match: | S000005929 | CHL1 | ATP-dependent DNA helicase CHL1 |
| CGD closest match: | CAL0000177726 | CHL1 | ATP-dependent DNA helicase CHL1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05190_1 | 49.18% | 911 | 0.0 | MIA_05190_1 |
| A0A0J9XED3_GEOCN | 45.12% | 902 | 0.0 | Similar to Saccharomyces cerevisiae YPL008W CHL1 Probable DNA helicase involved in sister-chromatid cohesion and genome integrity OS=Geotrichum candidum GN=BN980_GECA12s00142g PE=4 SV=1 |
| UniRef50_A0A0J9XED3 | 45.12% | 902 | 0.0 | Similar to Saccharomyces cerevisiae YPL008W CHL1 Probable DNA helicase involved in sister-chromatid cohesion and genome integrity n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XED3_GEOCN |
| A0A167ENN5_9ASCO | 39.07% | 901 | 0.0 | Chl1p OS=Sugiyamaella lignohabitans GN=CHL1 PE=4 SV=1 |
| A0A1E3PRD8_9ASCO | 39.52% | 916 | 0.0 | ATP-dependent RNA helicase CHL1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_81974 PE=4 SV=1 |
| A0A060TDE4_BLAAD | 36.54% | 903 | 0.0 | ARAD1B24046p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B24046g PE=4 SV=1 |
| CHL1_YARLI | 37.37% | 899 | 6e-178 | ATP-dependent DNA helicase CHL1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=CHL1 PE=3 SV=1 |
| CHL1_CANAL | 38.28% | 721 | 7e-152 | ATP-dependent DNA helicase CHL1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CHL1 PE=3 SV=1 |
| CHL1_YEAST | 33.37% | 911 | 4e-142 | ATP-dependent DNA helicase CHL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CHL1 PE=1 SV=1 |
| A0A1E4TGL2_9ASCO | 36.51% | 723 | 3e-136 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11308 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1148
Protein family membership
- DNA helicase (DNA repair), Rad3 type (IPR013020)
Domains and repeats
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Domain
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Domain
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Domain
Detailed signature matches
no IPR
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mobidb-lite (disord...)
Protein sequence
>MCA_06266_1 MTWLRDNNRKQFQDFEESNSNGGPSSSVPKWVREQYIKSKQQEIIEKFEKLQQDLKDALEIEEAERRSAQNINGKSSKRR HIAISTEQENMSNDDQFVLDDVASALECLDEKEQNVRAMSAKTRALLDELDQGSSLNADEQKNADNGDSIFATQGSQNRP LKIYFASRTHSQLSQFVGQLKLPHFPSVIPQDLLSHSKTISSDRSLIELFESIRHISLSSRKQLCIHPKISKYHSAQQIN DACLELQKSKSKTKSKSTSISKKLKITIDDKENECGCPYMLNPNDLRDRVKNREFRNASLIKIRDIEDLAELGRQKKVCP YYATRNVANNNWAEVISLPYQLLLQKESRESLGLDLKNSIVIIDEAHNLLDTISSIHSLSITYSQISQSLKALEFYKTKF ESRLTGRNLISLSKLIQVVKYLYQFFKAAKNKPFKETAPGSNIKITDFFPSDSTVDMINVHDLEKFVHQTHLVFKIEGYM EKILAEQKSVAAKDSNRAESAREKLVLSKVISFILAIGSPSWEGQFFFGRNEQNELQVEYILLDPSSKFKPIVEESRCII LAGGTMKPTDDFTNYLFPYLDPEQVSFFSCDHIIPDQNLTVLPISGNSGMNFNFTFAHRNNQAMIEKLGETILEICKCTP DGIVVFLPSYTYMASVFKIWKSSQINKVQTINDAIANTKEIFWEPHSGMTDQFSKNSTEMEEDSDQKSMKSMKRDYSTKE VLDNYSKYIFDRRKDPTSGGKTGAILFAVVGGKVSEGINFQDELARAVVMVGLPFPHAFSAEMVAKRKYIEQESLKRIQE QQGKGDKLPSSLEAQKKFAQSKAMEFYENICMKAVNQCVGRAIRHANDYAAIVLIDERYTKLNIQKKLSDWIRKGITSYP NNNATFSNAKTKLNNFFQSK
GO term prediction
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Cellular Component
None predicted.