Protein

MIA_05183_1

Length
398 amino acids


Browser: contig07:952319-953516-

Protein function

EGGNOG:0PKVSSTS1Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity)
SGD closest match:S000001450STS1Tethering factor for nuclear proteasome STS1
CGD closest match:CAL0000185317STS1Tethering factor for nuclear proteasome STS1

Protein alignments

%idAln lengthE-value
A0A167EEB8_9ASCO52.56%2151e-60Sts1p OS=Sugiyamaella lignohabitans GN=STS1 PE=3 SV=1
UniRef50_A0A167EEB852.56%2153e-57Sts1p n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167EEB8_9ASCO
MCA_06259_149.77%2194e-53MCA_06259_1
A0A060TCY1_BLAAD49.33%2251e-53ARAD1D03058p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D03058g PE=3 SV=1
A0A0J9XLN7_GEOCN51.98%2029e-53Similar to Saccharomyces cerevisiae YIR011C STS1 Protein required for localizing proteasomes to the nucleus OS=Geotrichum candidum GN=BN980_GECA32s02595g PE=3 SV=1
STS1_YARLI44.95%2187e-43Tethering factor for nuclear proteasome STS1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=STS1 PE=3 SV=1
A0A1E3PI37_9ASCO43.27%2084e-41Cut8-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83138 PE=3 SV=1
STS1_CANAL35.22%1592e-24Tethering factor for nuclear proteasome STS1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=STS1 PE=3 SV=1
A0A1E4TL53_9ASCO35.38%1954e-18Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30637 PE=3 SV=1
STS1_YEAST29.88%1642e-14Tethering factor for nuclear proteasome STS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STS1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0990

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_05183_1
MGLNAVLPPSTGWGFQFHASAAQNQHPHHHQQNMASSTSSNNSCDQTVPALHLSHLSVSRPKRKLNDDIAQDDSDEDSSI
QKLPSSTEPRRPSLRKQPSPPLASSIFSSPSILSTSPKNLAKIGKQSPLKHSKPAKRTRFDRMSGRPLPVARLVETLDKK
ALETLITALVQARPDTAPAIHALAPAVSVASALSALSAKLETIFLGLPYKGDQAGDYAYLRVRPAVDDFLAALADYTAHF
LPPNETQPSNSLAFLDAATLLLHKLPTWASPENNHARTVAYDRIAAAWVLALQEAAKRANGLGLAYGGWQSKLDNHNDLS
GQLLTPAASYLRNALRWMNDQHHQSNYNNHFYYNNADIPQSSAAAAGVAHPGPPPISAPVIPATGVFSKYSSGPSNWT

GO term prediction

Biological Process

GO:0031144 proteasome localization
GO:0071630 ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome

Molecular Function

None predicted.

Cellular Component

GO:0005634 nucleus