Protein

MIA_05159_1

Length
689 amino acids

Browser: contig07:874379-876449-

Protein function

EGGNOG:0PFJAFG06867.1DNA helicase
SGD closest match:S000001500HCS1DNA polymerase alpha-associated DNA helicase A
CGD closest match:CAL0000193898orf19.6199ATP-dependent 5'-3' DNA helicase

Protein alignments

%idAln lengthE-value
MCA_05827_159.855%6900.0MCA_05827_1
A0A0J9X5M0_GEOCN60.345%6960.0Similar to Saccharomyces cerevisiae YKL017C HCS1 Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis OS=Geotrichum candidum GN=BN980_GECA03s02870g PE=4 SV=1
A0A167FYS7_9ASCO53.266%6890.0ATP-dependent 5'-3' DNA helicase HCS1 OS=Sugiyamaella lignohabitans GN=HCS1 PE=4 SV=1
UniRef50_A0A167FYS753.266%6890.0ATP-dependent 5'-3' DNA helicase HCS1 n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167FYS7_9ASCO
A0A1E3PH35_9ASCO51.009%6940.0DNA helicase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_26851 PE=4 SV=1
A0A060T056_BLAAD51.248%6810.0ARAD1C05478p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C05478g PE=4 SV=1
Q6CFH6_YARLI46.444%6890.0YALI0B06897p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B06897g PE=4 SV=1
Q5AAW1_CANAL41.427%7296.26e-175ATP-dependent 5'-3' DNA helicase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6199 PE=4 SV=1
HCS1_YEAST42.219%6941.14e-166DNA polymerase alpha-associated DNA helicase A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HCS1 PE=1 SV=1
A0A1E4TKE7_9ASCO43.732%6866.31e-167Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_84103 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1581

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 689

Detailed signature matches

  1. Family IPR004483
    Helicase SMUBP-2/Hcs1-like
    1. TIGR00376
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. SM00487 (ultradead3)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. PF13086 (AAA_11)
  3. PF13087 (AAA_12)
  4. cd00046 (DEXDc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...

Protein sequence

>MIA_05159_1
MTSCSTKISENLSEALKEEQTADIDETNKLLNSLSPKQLANRGLAILNLVIGSIRTGTSGRPVISLELDPAVTQKNQELD
FGEIRNGDIVRISPYMNSADTKKKSQTKKKTKQHDTSDSKNDTFAIEGVVSINSNSLNVVIEEEFTNAIPSSDTRLWIVK
LTNNATYKRMEYALKSLKEIENPSRVQSILLGISDPSTSTSPPEIQYFNSELNDPQKDAIKFALGDSEVAVIHGPPGTGK
TYTLVEIIRQFVSQGKRVLVCGPSNISVDNILERLHNHIKGNKLIRIGHPARLLENNRIHSLDIVSKSNDYGQVVRELRE
EIDETLKKISKTKSWRERKEIYSNIRDLRKDYREREKKVIIDIILESQVVISTLHGAGSYSLRQVRRALGSTNKDLFDVI
IIDEVSQSLEAQCWIPVIDFPGAKKLIIAGDNKQLPPVVMSKNVQTKGVLEQTLFDRLEKLPCGKNIIKLLSIQYRMNKL
IMEFPSSYFYKSKLIADKSVAEKVIQSNEGEDIPPILWLDTQGYDYPEANSDESSAKGSRFEFSKYNENEAYLTRNYVFS
LVKKGVKPTEIGIIAPYSAQISLLSKIIHIRHQEIEISTVDGFQGREKVAIVLSLVRSNDTGEVGFLAEERRLNVAITRP
KKHLCIIGNTETLTKGNSKFLNQWVKWSYNKSEIDYPPIEDVLSSDLYM

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003677 DNA binding
GO:0005524 ATP binding

Cellular Component

None predicted.