Protein

MIA_05155_1

Length
1,269 amino acids

Browser: contig07:864854-868757-

Protein function

EGGNOG:0PHEFFG02781.1helicase (ski2
SGD closest match:S000004390SKI2Antiviral helicase SKI2
CGD closest match:CAL0000185019SKI2SKI complex RNA helicase subunit

Protein alignments

%idAln lengthE-value
MCA_05819_160.615%6830.0MCA_05819_1
A0A0J9XI75_GEOCN60.438%6850.0Similar to Saccharomyces cerevisiae YLR398C SKI2 Ski complex component and putative RNA helicase OS=Geotrichum candidum GN=BN980_GECA19s00120g PE=4 SV=1
A0A060SXD2_BLAAD56.681%6810.0ARAD1A03146p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03146g PE=4 SV=1
A0A167DAB9_9ASCO56.000%6500.0SKI complex RNA helicase subunit SKI2 OS=Sugiyamaella lignohabitans GN=SKI2 PE=4 SV=1
UniRef50_A0A167DAB956.000%6500.0SKI complex RNA helicase subunit SKI2 n=3 Tax=cellular organisms TaxID=131567 RepID=A0A167DAB9_9ASCO
A0A1E3PQU0_9ASCO51.395%6810.0Antiviral helicase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80957 PE=4 SV=1
Q6CH67_YARLI48.401%6880.0YALI0A11869p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A11869g PE=4 SV=2
Q5A337_CANAL48.052%6930.0SKI complex RNA helicase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SKI2 PE=4 SV=1
SKI2_YEAST46.930%6840.0Antiviral helicase SKI2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SKI2 PE=1 SV=2
A0A1E4THG6_9ASCO42.280%6938.25e-144Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_16251 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1170

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1269

Detailed signature matches

  1. Family IPR016438
    ATP-dependent RNA helicase Ski2
    1. PIRSF005198 (SKI2)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  6. Domain IPR025696
    rRNA-processing arch domain
    1. PF13234 (rRNA_proc-...)
  7. Domain IPR012961
    ATP-dependent RNA helicase Ski2, C-terminal
    1. SM01142 (DSHCT_2)
    2. PF08148 (DSHCT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00046 (DEXDc)
  4. cd00079 (HELICc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. putative Mg++ bind...
  3. nucleotide binding...
  4. ATP-binding site c...

Protein sequence

>MIA_05155_1
MSEIKSCLDSICKKIDSISCDSSFIDRSIIASSDHISEKDLSQENIIKTFLTPHPQFTSHWLDNLQELPPVDFLNDNTSQ
LFTPPQYKSVTGFKFHHAGLEGSIVGYSEYTISSEFSTKTSKNSLSLTREATSKADSVRGRPGYMPFAPGGVSILEENQK
IENLSRDTNGLYDIAPGLSRGLLDVLDDDKDVSAFSNENLVDMKDQEEISDSLDSPSEIDNQVSGSSDDENENDNYEDND
KDLEDESNNDSSVMQSTEIDVLLPNDITFGRIQNHIEPIPKSKDWAHEVDVNKTIKNFRELVPSMAKEYPFELDTFQKEA
VYHLEQGDSVFVAAHTSAGKTVVAEYAIAMASRNMTKAIYTSPIKALSNQKFRDFKDIFEDVGILTGDVQINSEASCLIM
TTEILRSMLYRGADLIRDVEFVIFDEVHYVNDQDRGVVWEEVIIMLPDHVKLILLSATVPNTFEFANWVGRTKQKDIYVI
STPKRPVPLEHYLWLKNKQIKIVNSDKKFLEEGYCAANNLLNPPAIPAGPKNGNKNDTNDTNGGRGGRGGRGGRGGSRGG
RGGRGGRGGGQLFNHSNSNNNSNRRRPNNNVHGKTTVLQLLQHLKKESLLPAVIFVFSQKQASSYASMITSIDYTTSKEK
SEIKMFVNTAISRLRKEDRELPQILEIRELLLRGIGTHHGGLLPIIKEIIEILFAKSLVKVLFATETFAMGLNLPTKTVV
FANTSKFDGHTFRQLYPGEYTQMAGRAGRRGLDTTGTVIIMTGSELSSQESFRELILGTPTKLQSQFRLTYNMILNLLRI
EALKVEEMIKRSFSENANQVMLPEHQKNVKINEEALTKLNREPCNFCDKDIEFVISKIDLYQKKSIELIKFFAKFVNGLS
AFPKGRIVVFKNGDEPRYVGLISNADTTRGTLNVFVLSRKPTDTFKDNAPFFPTIGGYIKRNMPNRFELAYNFRQISIPV
TSVEFITKLTVKFPPWILTKPKNPDYREAIQLLNSIFSFQDQWNEFHKDLKAVDMAIISKERAETFKLITTSQAISCPHF
VRHYSIEYERYKTQNNIEQLKQLIHGENMDLLPDYEQRIEVLKVLNYIDEDQNVLLKGRVACEITSGFELIITELILDNF
LASYEPEEIVSLLSVFLFQGASNVTSGPITPKLDYGKAKIKEVVTSTLDVFEQHSVLITQEETDFLENDRFALMEPIYEW
GRGMAFSDIMKLTIIPEGTIVRVITRLDEVCRQVMNAARIIGDATLYEKMELAQEKIKRDIVFCASLYL

GO term prediction

Biological Process

GO:0006401 RNA catabolic process

Molecular Function

GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

Cellular Component

None predicted.