Protein
MCA_05819_1
Length
1,272 amino acids
Gene name: SKI2
Description: Antiviral helicase SKI2
Browser: contigD:2420087-2423967+
RNA-seq: read pairs 2227, FPKM 21.6, percentile rank 43.4% (100% = highest expression)
Protein function
Annotation: | SKI2 | Antiviral helicase SKI2 | |
---|---|---|---|
KEGG: | K12599 | SKI2 | antiviral helicase SKI2 [EC:3.6.4.-] |
EGGNOG: | 0PHEF | FG02781.1 | helicase (ski2 |
SGD closest match: | S000004390 | SKI2 | Antiviral helicase SKI2 |
CGD closest match: | CAL0000185019 | SKI2 | SKI complex RNA helicase subunit |
Protein alignments
%id | Aln length | E-value | ||
---|---|---|---|---|
MIA_05155_1 | 60.76% | 1282 | 0.0 | MIA_05155_1 |
A0A0J9XI75_GEOCN | 59.56% | 1229 | 0.0 | Similar to Saccharomyces cerevisiae YLR398C SKI2 Ski complex component and putative RNA helicase OS=Geotrichum candidum GN=BN980_GECA19s00120g PE=4 SV=1 |
A0A060SXD2_BLAAD | 55.20% | 1250 | 0.0 | ARAD1A03146p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A03146g PE=4 SV=1 |
UniRef50_U4L5A6 | 48.89% | 1262 | 0.0 | Similar to Uncharacterized helicase C550.03c acc. no. O59801 n=210 Tax=Fungi TaxID=4751 RepID=U4L5A6_PYROM |
A0A1E3PQU0_9ASCO | 57.96% | 992 | 0.0 | Antiviral helicase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80957 PE=4 SV=1 |
Q5A337_CANAL | 49.44% | 1240 | 0.0 | SKI complex RNA helicase subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SKI2 PE=4 SV=1 |
SKI2_YEAST | 46.95% | 1280 | 0.0 | Antiviral helicase SKI2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SKI2 PE=1 SV=2 |
A0A167DAB9_9ASCO | 55.59% | 653 | 0.0 | SKI complex RNA helicase subunit SKI2 OS=Sugiyamaella lignohabitans GN=SKI2 PE=4 SV=1 |
Q6CH23_YARLI | 50.36% | 691 | 0.0 | YALI0A13519p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A13519g PE=4 SV=1 |
A0A1E4T9N9_9ASCO | 34.54% | 996 | 6e-158 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_58742 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0361
Protein family membership
- ATP-dependent RNA helicase Ski2 (IPR016438)
Domains and repeats
-
Domain
-
Domain
1
200
400
600
800
1000
1272
Detailed signature matches
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PIRSF005198 (SKI2)
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-
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PF00270 (DEAD)
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-
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SSF52540 (P-loop co...)
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-
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PF13234 (rRNA_proc-...)
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no IPR
Unintegrated signatures
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-
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cd00046 (DEXDc)
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cd00079 (HELICc)
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mobidb-lite (disord...)
Residue annotation
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ATP binding site c...
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putative Mg++ bind...
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nucleotide binding...
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ATP-binding site c...
Protein sequence
>MCA_05819_1 MSIEEAIDAIRTKSANIPSDAHIIPKLKPADPEELENDELSNENLIKKFLTPSAQFSNQWLDRLQELPKVDIQSNSLQLF TAPEYKSVTGVKFDRYGLEGKIVGYSEYTAPSEFSTKNAKNSLSINREPSSKADMVKGRPGFMPFAPGGLVSAQELTGHS DINISRDDNGLYSSAPGLSRGITEHFDAKTSHGGVEDKEFMAPTLFKESQESDDDEEDIEDLDDESEVVDLANNLDELIL EKDKDNKTAKVSTKIYSEDIDNLLPNEITFGRIKSTIDKIPKVKEWAHNVDVNKTINNFHELVPSMAKEFPFELDTFQKE AVYHLEQGDSVFVAAHTSAGKTVVAEYAIAMAIRNNTKAIYTSPIKALSNQKFRDFKEIFDDVGILTGDVQINPEASCLI LTTEILRSMLYRGADLIRDVECVIFDEVHYVNDQDRGVVWEEVIIMLPEHIKLILLSATVPNTFEFGNWVGRTKQKDIYV ISTPKRPVPLEHYIWTKNRQIKIVDADKKFLEDGYKTVCNLINPPPPKGDDRNGKGGGQGQGGRGGSARGGGRGGRGGRG GRGGRGGGQLFIPSGGTSYGNQNRRFNSNTHGKTTFIQLLTHLRKENLLPAVIFVFSQKKATEYAQMLQSIDYCTNREKS EIRMFVDQAISRLKEEDRDLPQIHFVSELLSRGIGIHHGGLLPIVKEIIEILFAKSLVKVLFATETFAMGLNLPTKTVIF ASTRKHDGHSFRDLLPGEYTQMAGRAGRRGLDTFGTVMLMVSDSPPPADDLKKLILGTPTKLKSQFRLTYNMILNLLRIE ALRIEEMIKRSFSENANQVMLPEHQKNVKLKEESLAKLTREKCSNCDENLEKFAAAVKQEREIYQEILDASIRLYNAKNL FSRGRLIIFKLPNGVRMVGIILNFVAGSRAFTVLGASDSTPDPSDKVPYYSMIPGYCERNMNTRFKVASRYKIYRISLSD IEFIVRIQLRSEIDGYNNPSSKSFKELTKELKVAFVYQNKWNEATNKNISNTLDIASKQEERKKLIKELATFKCIKCPKF VQHYTIASEILCIEDQINGLKQLISSENMELLPDYEQRVAVLQDLNYIDESQNVLLKGRVACEISTGFELIITELVLDNF LASYEPEEIVALLSVFLFQGSNKDNGAPSKSVTPKLDIGRARIVEVVEQVLGVFEKYNVLVTPEEAEFLEKDRFALMEPV YEWGRGMAFKEIMRMTDVPEGTIVRVITRLDEVCRQVMNAAKIIGDTTLYDKMAVAQEKIKRDIVFCASLYL
GO term prediction
Biological Process
GO:0006401 RNA catabolic process
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
Cellular Component
None predicted.