Protein
MIA_05093_1
Length
485 amino acids
Browser: contig07:699227-700736+
Protein function
| EGGNOG: | 0PI87 | DDI1 | Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control and may be involved in the regulation of exocytosis (By similarity) |
|---|---|---|---|
| SGD closest match: | S000000945 | DDI1 | DNA damage-inducible protein 1 |
| CGD closest match: | CAL0000199868 | DDI1 | Ddi1p |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_06234_1 | 55.53% | 380 | 7e-132 | MCA_06234_1 |
| A0A0J9X6S1_GEOCN | 49.44% | 358 | 9e-111 | Similar to Saccharomyces cerevisiae YER143W DDI1 DNA damage-inducible v-SNARE binding protein with a role in suppression of protein secretion OS=Geotrichum candidum GN=BN980_GECA03s02826g PE=4 SV=1 |
| UniRef50_A0A0J9X6S1 | 49.44% | 358 | 2e-107 | Similar to Saccharomyces cerevisiae YER143W DDI1 DNA damage-inducible v-SNARE binding protein with a role in suppression of protein secretion n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X6S1_GEOCN |
| A0A060T043_BLAAD | 48.98% | 343 | 5e-101 | ARAD1C05258p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C05258g PE=4 SV=1 |
| A0A167DSM5_9ASCO | 45.45% | 363 | 5e-98 | Ddi1p OS=Sugiyamaella lignohabitans GN=DDI1 PE=4 SV=1 |
| DDI1_YEAST | 38.33% | 360 | 4e-61 | DNA damage-inducible protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DDI1 PE=1 SV=1 |
| DDI1_YARLI | 33.14% | 347 | 3e-58 | DNA damage-inducible protein 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DDI1 PE=3 SV=1 |
| A0A1D8PFX6_CANAL | 35.21% | 355 | 9e-50 | Ddi1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=DDI1 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0487
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
485
Detailed signature matches
no IPR
Unintegrated signatures
-
-
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cd01769 (UBL)
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mobidb-lite (disord...)
Residue annotation
-
Ubq - UCH interact...
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Ubq - E2 interacti...
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Ubq - CUE interact...
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Catalytic residue ...
-
catalytic motif cd...
Protein sequence
>MIA_05093_1 MKLTISFDADTFPNLQTLTMEIDAGKDMTLNDLLAYIEAESGVKRETMVLMHRGKVMKDTSSLSPSVTLENLDIKDGDLL LPQQEQQPQQEQPQQQLGITLPTNSNAEATDAGSGHTWTKLFQDMEVIRKHMLTNPVLRSGVIQQYPRLEAVVDDPLRFR EELVKIEQSRVKQEITKQAAMKKLEEDPYDEESQKMILKNIQEEAIMENFHKAMEHNPELFASVTMLFINTTVNNRPVKA FVDSGAQATIMSPACAERCGIAHLIDERFQGMAMGVGTARILGRIHSVPIQIGDQFLATSFTVMEGKGVDFLLGLDMLKK HRAMIDLKDNVLHIADVTVPFLPEAEIPNSGLFFQDAGSSAGSDTKTNTGPSTSNEPGSAGWSSSGPSGSASGSATSVAS GSGKKPDNSVGSSSSSKTTTDPAAATAQTGATASKPRTGPSPTPLKYTEDTVQSLMAMGYTRNKVLEALTLADGNPDLAA NLLLG
GO term prediction
Biological Process
GO:0006508 proteolysis
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
GO:0005515 protein binding
Cellular Component
None predicted.