MIA_05067_1

Protein

Length

475 amino acids

Browser: contig07:620058-621486-

Protein function

EGGNOG:	0PGQF	FG08982.1	complex, subunit
SGD closest match:	S000006180	APM1	AP-1 complex subunit mu-1-I
CGD closest match:	CAL0000186413	APM1	Apm1p

Protein alignments

	%id	Aln length	E-value
MCA_06028_1	77.963%	481	0.0	MCA_06028_1
A0A0J9X6B2_GEOCN	67.568%	481	0.0	Similar to Saccharomyces cerevisiae YPL259C APM1 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1) OS=Geotrichum candidum GN=BN980_GECA03s00197g PE=3 SV=1
A0A060THJ5_BLAAD	58.228%	474	0.0	ARAD1D31526p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D31526g PE=3 SV=1
A0A161HFH7_9ASCO	51.724%	522	0.0	Apm1p OS=Sugiyamaella lignohabitans GN=APM1 PE=3 SV=1
A0A1E3PGC3_9ASCO	51.633%	490	2.34e-172	Clathrin adaptor, mu subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52754 PE=3 SV=1
UniRef50_A0A1E3PGC3	51.633%	490	6.34e-169	Clathrin adaptor, mu subunit n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PGC3_9ASCO
A0A1E4TG63_9ASCO	50.426%	470	2.19e-170	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_110094 PE=3 SV=1
Q6CEZ3_YARLI	50.418%	478	1.43e-168	YALI0B11682p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11682g PE=3 SV=1
AP1M1_YEAST	46.545%	492	5.32e-160	AP-1 complex subunit mu-1-I OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APM1 PE=1 SV=2
Q5AJY4_CANAL	45.168%	476	4.80e-149	Apm1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APM1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2859

Protein family membership

Clathrin adaptor, mu subunit (IPR001392)

Domains and repeats

Domain
3 - 142
Longin-like domain (IPR011012)
AP complex, mu/sigma subunit (IPR022775)
156 - 468
Mu homology domain (IPR028565)

1 50 100 150 200 250 300 350 400 450 475

Detailed signature matches

IPR001392

Clathrin adaptor, mu subunit
1. PIRSF005992 (AP_com...)
  
  2 - 469
  
  PIRSF
  PIRSF005992 (AP_complex_mu)
2. PR00314 (CLATHRINADPT)
  
  251 - 278
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  13 - 33
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  321 - 336
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  158 - 186
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  102 - 129
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  361 - 372
  
  PRINTS
  PR00314 (CLATHRINADPT)
IPR011012

Longin-like domain
1. SSF64356 (SNARE-like)
  
  3 - 142
  
  SUPERFAMILY
  SSF64356 (SNARE-like)
IPR022775

AP complex, mu/sigma subunit
1. PF01217 (Clat_adapt...)
  
  3 - 129
  
  Pfam
  PF01217 (Clat_adaptor_s)
IPR028565

Mu homology domain
1. SSF49447 (Second do...)
  
  417 - 463
  
  SUPERFAMILY
  SSF49447 (Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor)
  
  156 - 390
  
  SUPERFAMILY
  SSF49447 (Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor)
2. PF00928 (Adap_comp_sub)
  
  156 - 468
  
  Pfam
  PF00928 (Adap_comp_sub)
3. PS51072 (MHD)
  
  167 - 468
  
  PROSITE profiles
  PS51072 (MHD)
IPR018240

Clathrin adaptor, mu subunit, conserved site
1. PS00990 (CLAT_ADAPT...)
  
  156 - 176
  
  PROSITE patterns
  PS00990 (CLAT_ADAPTOR_M_1)

no IPR

Unintegrated signatures

G3DSA:2.60.40...

163 - 244

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)

294 - 422

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)

423 - 463

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)
G3DSA:3.30.45...

1 - 144

GENE3D
G3DSA:3.30.450.60 (G3DSA:3.30.450.60)
cd09250 (AP-1_Mu1_C...)

153 - 464

CDD
cd09250 (AP-1_Mu1_Cterm)
mobidb-lite (disord...)

224 - 246

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

heterotetramer int...

165Y

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

185D

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

187K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

189I

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

190R

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

200N

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

210K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

252E

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

255K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

279K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

286R

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

288S

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

303D

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

315T

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

317K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

323R

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

328H

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

347T

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

352I

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

355P

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

356E

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

365K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

371Q

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

372E

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

374K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

424K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

425F

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

426D

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

429Y

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

438R

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

439Y

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

440L

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

441K

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

451A

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

452L

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

453P

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

454W

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

455V

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

460Q

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

462G

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)

463E

heterotetramer interface
165Y, 185D, 187K, 189I, 190R, 200N, 210K, 252E, 255K, 279K, 286R, 288S, 303D, 315T, 317K, 323R, 328H, 347T, 352I, 355P, 356E, 365K, 371Q, 372E, 374K, 424K, 425F, 426D, 429Y, 438R, 439Y, 440L, 441K, 451A, 452L, 453P, 454W, 455V, 460Q, 462G, 463E
CDD
cd09250 (AP-1_Mu1_Cterm)
signal peptide bin...

171F

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

172L

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

173D

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

200N

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

327T

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

426D

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

428P

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

453P

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

454W

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

455V

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

456R

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

458L

signal peptide binding site
171F, 172L, 173D, 200N, 327T, 426D, 428P, 453P, 454W, 455V, 456R, 458L
CDD
cd09250 (AP-1_Mu1_Cterm)

Protein sequence

>MIA_05067_1
MTVSAIFFLDSKGKPLLSRNYRGDLPITSAIEAFPSLLTEAQQRSTVVPPCINRNGINYLFITHSDIYVLALSKQNTNAS
AVLFFLHQLVQTLIQYLNALDEETIRDNFVIIYELLDEMMDFGHPQISDYKVLQEYITQDSHPASASASSIVTNSVSWRP
EGIFYKKNELFLDVVESVDFLLGADGKIIRNDVQGKVVVNAYLSGMPVLKLGLNDVDKKILEQQKKEEEEGVDHAQAPRP
RKKIGSKQVHMEDIKFHQCVQLDQFEDDRTIMFTPPDGKFDLLTYRVSNVSQRPLFAVDATVDLKSHSRAIINVTVKSQF
RKRSTATHVEIQIPVPRDADSPRFKTTAGTVIYAPELNAVVWKIKDFPGGQEYKMKAQVSLSSLAGEFDDNDEQLTSGAS
QTDSANAYRTATLTRIKNQPIRVKFDIPYFAVSGLQVRYLKVEEARLQYQALPWVRYLTQSGEEFAIRLPPKNVF

GO term prediction

Biological Process

GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

None predicted.

Cellular Component

GO:0030131 clathrin adaptor complex

Filter view on

Entry type

Status

Per-residue features