MCA_06028_1

Protein

Length

478 amino acids

RNA-seq: read pairs 1946, FPKM 50.2, percentile rank 65.5% (100% = highest expression)

Protein function

KEGG:	K12393	AP1M	AP-1 complex subunit mu
EGGNOG:	0PGQF	FG08982.1	complex, subunit
SGD closest match:	S000006180	APM1	AP-1 complex subunit mu-1-I
CGD closest match:	CAL0000186413	APM1	Apm1p

Protein alignments

	%id	Aln length	E-value
MIA_05067_1	77.96%	481	0.0	MIA_05067_1
A0A0J9X6B2_GEOCN	65.77%	485	0.0	Similar to Saccharomyces cerevisiae YPL259C APM1 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1) OS=Geotrichum candidum GN=BN980_GECA03s00197g PE=3 SV=1
A0A060THJ5_BLAAD	57.74%	478	0.0	ARAD1D31526p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D31526g PE=3 SV=1
A0A161HFH7_9ASCO	52.65%	528	0.0	Apm1p OS=Sugiyamaella lignohabitans GN=APM1 PE=3 SV=1
A0A1E3PGC3_9ASCO	52.93%	495	6e-170	Clathrin adaptor, mu subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52754 PE=3 SV=1
UniRef50_A0A1E3PGC3	52.93%	495	2e-166	Clathrin adaptor, mu subunit n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PGC3_9ASCO
A0A1E4TG63_9ASCO	49.58%	474	2e-164	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_110094 PE=3 SV=1
Q6CEZ3_YARLI	47.72%	482	2e-158	YALI0B11682p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11682g PE=3 SV=1
AP1M1_YEAST	45.18%	498	4e-151	AP-1 complex subunit mu-1-I OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APM1 PE=1 SV=2
Q5AJY4_CANAL	46.46%	480	2e-146	Apm1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=APM1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1950

Protein family membership

Clathrin adaptor, mu subunit (IPR001392)

Domains and repeats

Domain
3 - 142
Longin-like domain (IPR011012)
AP complex, mu/sigma subunit (IPR022775)
156 - 471
Mu homology domain (IPR028565)

1 50 100 150 200 250 300 350 400 450 478

Detailed signature matches

IPR001392

Clathrin adaptor, mu subunit
1. PIRSF005992 (AP_com...)
  
  2 - 472
  
  PIRSF
  PIRSF005992 (AP_complex_mu)
2. PR00314 (CLATHRINADPT)
  
  359 - 370
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  249 - 276
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  13 - 33
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  158 - 186
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  319 - 334
  
  PRINTS
  PR00314 (CLATHRINADPT)
  
  102 - 129
  
  PRINTS
  PR00314 (CLATHRINADPT)
IPR011012

Longin-like domain
1. SSF64356 (SNARE-like)
  
  3 - 142
  
  SUPERFAMILY
  SSF64356 (SNARE-like)
IPR022775

AP complex, mu/sigma subunit
1. PF01217 (Clat_adapt...)
  
  3 - 129
  
  Pfam
  PF01217 (Clat_adaptor_s)
IPR028565

Mu homology domain
1. SSF49447 (Second do...)
  
  156 - 388
  
  SUPERFAMILY
  SSF49447 (Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor)
  
  421 - 471
  
  SUPERFAMILY
  SSF49447 (Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor)
2. PF00928 (Adap_comp_sub)
  
  156 - 471
  
  Pfam
  PF00928 (Adap_comp_sub)
3. PS51072 (MHD)
  
  167 - 471
  
  PROSITE profiles
  PS51072 (MHD)
IPR018240

Clathrin adaptor, mu subunit, conserved site
1. PS00990 (CLAT_ADAPT...)
  
  156 - 176
  
  PROSITE patterns
  PS00990 (CLAT_ADAPTOR_M_1)

no IPR

Unintegrated signatures

G3DSA:2.60.40...

163 - 242

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)

428 - 467

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)

292 - 427

GENE3D
G3DSA:2.60.40.1170 (G3DSA:2.60.40.1170)
G3DSA:3.30.45...

1 - 144

GENE3D
G3DSA:3.30.450.60 (G3DSA:3.30.450.60)
cd09250 (AP-1_Mu1_C...)

153 - 471

CDD
cd09250 (AP-1_Mu1_Cterm)

Residue annotation

heterotetramer int...

165Y

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

185D

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

187K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

189I

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

190H

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

200N

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

210K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

250E

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

253K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

277K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

284R

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

287N

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

301A

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

313T

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

315K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

321R

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

326F

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

345T

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

350V

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

353P

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

354E

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

363K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

369V

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

370E

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

372K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

428K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

429F

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

430E

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

433Y

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

442R

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

443Y

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

444L

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

445K

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

455S

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

456L

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

457P

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

458W

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

459V

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

464Q

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

466G

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)

467E

heterotetramer interface
165Y, 185D, 187K, 189I, 190H, 200N, 210K, 250E, 253K, 277K, 284R, 287N, 301A, 313T, 315K, 321R, 326F, 345T, 350V, 353P, 354E, 363K, 369V, 370E, 372K, 428K, 429F, 430E, 433Y, 442R, 443Y, 444L, 445K, 455S, 456L, 457P, 458W, 459V, 464Q, 466G, 467E
CDD
cd09250 (AP-1_Mu1_Cterm)
signal peptide bin...

171F

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

172L

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

173D

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

200N

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

325S

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

430E

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

432P

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

457P

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

458W

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

459V

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

460R

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

462L

signal peptide binding site
171F, 172L, 173D, 200N, 325S, 430E, 432P, 457P, 458W, 459V, 460R, 462L
CDD
cd09250 (AP-1_Mu1_Cterm)

Protein sequence

>MCA_06028_1
MTISAIFFLDSKGKPLLSRNYKGDIPITSAIEEFPKILVSAQQESTSIPPCINKNGINYIFITHNDIFILGLSKQNSNAS
AVLYFFHQLLETLTQYLNNLDEETIRDNFVIIYELLDEMMDFGHPQISDYKVLQEYITQDSHPASASASSIVTNAVSWRP
DGIFYKKNELFLDVIESVEFLLGADGKIIHNNVLGKVSVNAYLSGMPNLKLGLNDVDKKILQQQARERETGEVEPTKPKK
RIGSKQVHLEDVKFHQCVELDQFEADRTITFTPPDGKFDLLTYRVSNLASRPLFLVDATVAVKSRSRAIVNVTVKSQFRK
RSTASFVEISIPVPPDADSPKFKTTAGTVVYAPEKNAIVWKLKDFPGGVEYKMKTQIQLSSLTGQMDDEEFYNENTNGVS
SGAASVDSAVAFKTATINRIKTQPISVKFEIPYFAVSGLQVRYLKVEEPRLKYQSLPWVRYLTQSGEYQIRLPPQNVF

GO term prediction

Biological Process

GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport

Molecular Function

None predicted.

Cellular Component

GO:0030131 clathrin adaptor complex

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Entry type

Status

Per-residue features