Protein

MIA_05063_1

Length
313 amino acids

Browser: contig07:615416-616358-

Protein function

EGGNOG:0PKDXPGUG_05499NUDIX domain-containing protein
SGD closest match:S000004141PCD1Peroxisomal coenzyme A diphosphatase 1, peroxisomal
CGD closest match:CAL0000194979PCD18-oxo-dGTP diphosphatase

Protein alignments

%idAln lengthE-value
MCA_06040_147.321%3368.79e-90MCA_06040_1
A0A0J9X4H1_GEOCN44.478%3358.09e-69Similar to Saccharomyces cerevisiae YLR151C PCD1 Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives OS=Geotrichum candidum GN=BN980_GECA03s00175g PE=4 SV=1
UniRef50_A0A0J9X4H144.478%3351.66e-65Similar to Saccharomyces cerevisiae YLR151C PCD1 Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4H1_GEOCN
A0A060TDB8_BLAAD42.308%3121.39e-50ARAD1D46706p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D46706g PE=4 SV=1
A0A167C6G0_9ASCO38.961%3081.88e-48Pcd1p OS=Sugiyamaella lignohabitans GN=PCD1 PE=4 SV=1
Q6C0C1_YARLI33.133%3322.39e-37YALI0F26037p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26037g PE=4 SV=1
A0A1E4TJ65_9ASCO33.688%2821.72e-29Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_361 PE=4 SV=1
A0A1D8PU14_CANAL32.099%2438.74e-188-oxo-dGTP diphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PCD1 PE=4 SV=1
PCD1_YEAST30.070%2866.69e-14Peroxisomal coenzyme A diphosphatase 1, peroxisomal OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCD1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4850
Predicted cleavage: 14

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 313

Detailed signature matches

  1. Domain IPR015797
    NUDIX hydrolase domain-like
    1. SSF55811 (Nudix)
  2. Domain IPR000086
    NUDIX hydrolase domain
    1. PS51462 (NUDIX)
    2. PF00293 (NUDIX)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.90.79.10
  2. cd03426 (CoAse)

Residue annotation

  1. putative active si...
  2. putative CoA bindi...
  3. nudix motif cd03426
  4. metal binding site...

Protein sequence

>MIA_05063_1
MLSSTTKTVLARLQAFGHGTVPSAEIPTPSFAAWDSVPAKRRAAVLVVLFETKNPVTNRVELSTVLTTRAAHLSSFSGHV
ALPGGKVDSEEETAREAARREASEEIGFPAMLPENDPIVDVSRFPAYLSRNLLAVAPFVAYIPSPTQIPPLYGLPDVLPD
NLEDVLRAGGEVGEVFSVPLRHFLYLHPPGSTPGAAPGRTPPVTPWYTGGDAIWGGLSWWMHHFAVRRRVNKLPGEPAHF
SVWGLTARILLDVARVGYAQTPEMRHTHNVGDEGLIEALVRGGHMAVARSKRDVSFNFTKAFGRDSPLLKSRL

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.