Protein

MCA_06040_1

Length
332 amino acids

Browser: contigD:3095562-3096561-

RNA-seq: read pairs 1201, FPKM 44.6, percentile rank 62.8% (100% = highest expression)

Protein function

EGGNOG:0PKDXPGUG_05499NUDIX domain-containing protein
SGD closest match:S000004141PCD1Peroxisomal coenzyme A diphosphatase 1, peroxisomal
CGD closest match:CAL0000194979PCD18-oxo-dGTP diphosphatase

Protein alignments

%idAln lengthE-value
MIA_05063_147.32%3366e-88MIA_05063_1
A0A0J9X4H1_GEOCN42.33%3261e-59Similar to Saccharomyces cerevisiae YLR151C PCD1 Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives OS=Geotrichum candidum GN=BN980_GECA03s00175g PE=4 SV=1
UniRef50_A0A0J9X4H142.33%3263e-56Similar to Saccharomyces cerevisiae YLR151C PCD1 Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4H1_GEOCN
A0A060TDB8_BLAAD40.19%3165e-52ARAD1D46706p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D46706g PE=4 SV=1
Q6C0C1_YARLI36.18%3405e-44YALI0F26037p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F26037g PE=4 SV=1
A0A167C6G0_9ASCO37.54%3337e-44Pcd1p OS=Sugiyamaella lignohabitans GN=PCD1 PE=4 SV=1
A0A1D8PU14_CANAL32.23%2117e-238-oxo-dGTP diphosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PCD1 PE=4 SV=1
PCD1_YEAST30.04%2432e-20Peroxisomal coenzyme A diphosphatase 1, peroxisomal OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCD1 PE=1 SV=1
A0A1E4TJ65_9ASCO29.19%2988e-21Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_361 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.7103
Predicted cleavage: 41

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 332

Detailed signature matches

  1. Domain IPR015797
    NUDIX hydrolase domain-like
    1. SSF55811 (Nudix)
  2. Domain IPR000086
    NUDIX hydrolase domain
    1. PS51462 (NUDIX)
    2. PF00293 (NUDIX)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.90.79.10
  2. cd03426 (CoAse)

Residue annotation

  1. putative active si...
  2. putative CoA bindi...
  3. nudix motif cd03426
  4. metal binding site...

Protein sequence

>MCA_06040_1
MISSTSKTALSRLRAYGAKVSSTAHPETSPWYTSPLFRRAAVLVILFETRNPITKAIELSTVLTTRSDHLSSFSGQVAFP
GGKADFDHESIYMAARREAMEEINFPPYNAEASTEEKQSSTITKYSNDIEHIGELPSYLARNLLVVSPSIAYVKTPEHCI
QDPTQLPESYSGLPHVLGTNQELKTVLRESGEVAHVFSAPIKHFLYATEPENSRNRNSHAHPWYHGAVGNWNGLKWWLHY
FNVLRRTGKQVGEPSHFLVWGLTARIIIDTARIAYEMKPEVDYNEIVGDEAVLNELVKGGYMHQPRSKADLNFPFKKIFG
DRLQELRCKPSI

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.