Protein

MIA_04947_1

Length
1,269 amino acids

Browser: contig07:242802-246612+

Protein function

EGGNOG:0PG2AMIP1DNA polymerase gamma
SGD closest match:S000005857MIP1DNA polymerase gamma
CGD closest match:CAL0000176297orf19.3431DNA-directed DNA polymerase gamma (Fragment)

Protein alignments

%idAln lengthE-value
MCA_04946_163.507%10550.0MCA_04946_1
A0A0J9XAM4_GEOCN60.852%10090.0Similar to Saccharomyces cerevisiae YOR330C MIP1 Catalytic subunit of the mitochondrial DNA polymerase OS=Geotrichum candidum GN=BN980_GECA07s00846g PE=4 SV=1
A0A060T2W1_BLAAD55.874%10130.0ARAD1A11572p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11572g PE=4 SV=1
A0A167EFM7_9ASCO55.700%10000.0DNA-directed DNA polymerase gamma MIP1 OS=Sugiyamaella lignohabitans GN=MIP1 PE=4 SV=1
UniRef50_A0A167EFM755.700%10000.0DNA-directed DNA polymerase gamma MIP1 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167EFM7_9ASCO
A0A1E3PH76_9ASCO53.472%10080.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_60318 PE=4 SV=1
Q6C143_YARLI47.283%10490.0YALI0F19404p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F19404g PE=4 SV=1
A0A1E4TAT0_9ASCO48.968%10170.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32312 PE=4 SV=1
DPOG_YEAST47.225%10270.0DNA polymerase gamma OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MIP1 PE=1 SV=3
A0A1D8PPN3_CANAL46.125%10580.0DNA-directed DNA polymerase gamma (Fragment) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3431 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9996
Predicted cleavage: 30

Protein family membership

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1269

Detailed signature matches

  1. Family IPR002297
    DNA-directed DNA-polymerase, family A, mitochondria
    1. PR00867 (DNAPOLG)
  2. Domain IPR012337
    Ribonuclease H-like domain
    1. SSF53098 (Ribonucle...)
    2. G3DSA:3.30.42...
  3. Domain IPR001098
    DNA-directed DNA polymerase, family A, palm domain
    1. SM00482 (polaultra3)
    2. PF00476 (DNA_pol_A)
  4. SITE IPR019760
    DNA-directed DNA polymerase, family A, conserved site
    1. PS00447 (DNA_POLYME...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.30.70...
  3. SSF56672 (DNA/RNA p...)
  4. mobidb-lite (disord...)

Protein sequence

>MIA_04947_1
MISSAASRWRLSRRLFSTCRTLPRPVNTTQSSSPSSEEPPRINAVGIQYLPSKLHTKIFGSPVPTLKTTADHDDYITRLS
IRHLKNNGLYGKKTTAYPTIDIDVPSISGKTLDEHFYKIGLSSAEPYLSKAKKFAAGDIPPMPKQQDWIKKSGWTKYAKG
AAPVSVDYPDDPDALVFDVEVLYKIHDFAVIAVAASPTAWYCWLSPWLLGESQNQRQLIPLGSKEEKLVIGHNVSYDRKR
IKDEYSVNLTNSMFVDTMSLHIAVNGMCSRQRMSWMKVRKVKNQIDSGETSEESAFELSAEIEENPWVNVSTLNSLADVG
YLHCGIQHDKSARDYFGTYSREQVLEELNMLIDYCARDVDVTYKVYKALLPRFIDVVPHPVSFAALRHMGSLFLPINESW
EKYLKDTEECYNAANDELQNNLINLAEEAVALKDTPEKWQADPWLSQLDWTITPIKMVKPKKKGEQPRPAKRQKLPGFPK
WYKDLFPSIGAPMNISVRSRTALILLRLRWDNYPIIWSTVHGFVFRVPITQKQRCLDKNYPFADMNTETDMSLKDDPKVV
YFKVPHKDGPKARCVSPMASSYREYFDKGILSSELDLAAKAIKVNAACSYWTSNRERVLSQMTVWSNEVDMGIPTKNEKD
FGMILPSLVPMGTITRRAVEKTWLTASNAKKNRIGSEQKAMVRTPPGYKFVGADVDSEELWIASLVGDSMFKMHGGTALG
WMTLEGSKNEGTDLHSKTASILGISRNDAKVFNYGRIYGAGLAFAQQLLKQFNPTLTEKEVQDTAMRLYAATKGTKTKSK
TLGFEGSGGFWRNGSESLIFNRLEEMANQDAPRTPVLGAAITEALKRQYLKASPFLPSRINWNIQSSGVDYLHLLITSMA
YLTKKYDIDARLFITVHDEIRYMVKDEDVDRAALALQISNLWTRAMFSLQLGIKELPYGVAFFSAVDVDHVLRKEVNLDC
VTPSHPNVIEPGYSMDIYELVKKCKSLAKNGVEPVDSPNLDEIKFTPELSVTEEIEEGHGPMVPYIAAQIAANSEELSLV
EKLATEENPDWDQFLGSTDDDAATKSTGGEADTKEIKELMRELETLTTAPEPVKTPKKRGPKPKTASKTKKNNSKGKKTA
TEKNKSQADKTEKSTLDSDKDTPVGAQVSEPKRRYTRRTTSNLHPLFVLPPELASLTSPDTPEGRSRLDKWRRERAQENR
SRMESFHTNKQSYSKPKLDELLMQYECQSPKMAVVPEEFFSPEEMYNIFGNDLRVHKNQTNEDRRRRAY

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity

Cellular Component

GO:0005760 gamma DNA polymerase complex