Protein
MCA_04946_1
Length
1,159 amino acids
Gene name: MIP1
Description: DNA polymerase gamma; mitochondrial
Browser: contigC:4490755-4494306+
RNA-seq: read pairs 1386, FPKM 14.8, percentile rank 33.7% (100% = highest expression)
Protein function
| Annotation: | MIP1 | DNA polymerase gamma; mitochondrial | |
|---|---|---|---|
| KEGG: | K02332 | POLG1 | DNA polymerase gamma 1 [EC:2.7.7.7] |
| EGGNOG: | 0PG2A | MIP1 | DNA polymerase gamma |
| SGD closest match: | S000005857 | MIP1 | DNA polymerase gamma |
| CGD closest match: | CAL0000176297 | orf19.3431 | DNA-directed DNA polymerase gamma (Fragment) |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04947_1 | 63.51% | 1055 | 0.0 | MIA_04947_1 |
| A0A0J9XAM4_GEOCN | 62.37% | 1031 | 0.0 | Similar to Saccharomyces cerevisiae YOR330C MIP1 Catalytic subunit of the mitochondrial DNA polymerase OS=Geotrichum candidum GN=BN980_GECA07s00846g PE=4 SV=1 |
| A0A060T2W1_BLAAD | 55.50% | 1072 | 0.0 | ARAD1A11572p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11572g PE=4 SV=1 |
| A0A167EFM7_9ASCO | 55.33% | 1014 | 0.0 | DNA-directed DNA polymerase gamma MIP1 OS=Sugiyamaella lignohabitans GN=MIP1 PE=4 SV=1 |
| UniRef50_A0A167EFM7 | 55.33% | 1014 | 0.0 | DNA-directed DNA polymerase gamma MIP1 n=1 Tax=Sugiyamaella lignohabitans TaxID=796027 RepID=A0A167EFM7_9ASCO |
| A0A1E3PH76_9ASCO | 52.76% | 1033 | 0.0 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_60318 PE=4 SV=1 |
| Q6C143_YARLI | 47.37% | 1064 | 0.0 | YALI0F19404p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F19404g PE=4 SV=1 |
| A0A1E4TAT0_9ASCO | 50.61% | 976 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32312 PE=4 SV=1 |
| DPOG_YEAST | 48.05% | 1028 | 0.0 | DNA polymerase gamma OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MIP1 PE=1 SV=3 |
| A0A1D8PPN3_CANAL | 46.49% | 1067 | 0.0 | DNA-directed DNA polymerase gamma (Fragment) OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3431 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9867
Predicted cleavage: 36
Protein family membership
Domains and repeats
-
Domain
1
200
400
600
800
1000
1159
Detailed signature matches
no IPR
Unintegrated signatures
Residue annotation
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heterodimer interf...
-
DNA binding site c...
-
active site cd08641
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catalytic site cd0...
Protein sequence
>MCA_04946_1 MNIISLRSPCTTIGIRFRRPSAIFLRRLTNLSEKGIETGKENDLRINPVGIQYLPSNLQNQLFKSKSTIIPNRSTSKLSS SSLKKLQEIEDKNLVQLAIKHLKNNDLYGKKTSILPPVDLKLPKLVGDSLDEHFYKLGVYASEPYLSKAKQFASQSIPDI PTPDRWVQQSGWTKYHANGNTPIKVDYPDEKDALVLDVEVLYKISDFPIFAVAVSNSAWYCWVSPWFLGESESPRHLIPL GSEEEKLVIGHNVSYDRQRIKEEYSIHLSNSMFLDTMSLHIAVSGMCSRQRPDMIRVKRAKKSSEDVERDATAFSLLDEE IGENPWIQVSSLNNLADVAYLHCGIQHDKGVRDSFGKMTRQEARDQFNKLVDYCARDVATTFEVYKHLLPKFLTVIPHPV SFAGIRHMGSLFLPINHSWEKYLADSERCYEEHQGKLYDSLVKLANTAVELRDTPEKWRSDPWLRQLDWTITPIKMVKPK KKGELPRPAKRQKLPGYPKWYKDLFPTANSPMNISVRCRTAVFLLRLQWDGNPLIWSQSHGFVFKVPKANKQMFLDKNYS LADMNNDPDLSFKDDVNSVYFKIPHKDGPKAKCTSPMTASYYDYFDKKILSSEYDLAAEALKVNMSCSYWAHNRERAKSQ LAIWSDDTNMGIKVQSPKDFGMILPSLITMGTVTRRAVEKTWLTASNAKKNRIGSEQKSMIQAPPGYKFVGADVDSEELW IASLLGDSMFKIHGGTALGWMTLEGTKSEGTDLHSKTASILGISRNEAKVFNYGRIYGAGVTFAAQLLKQFNPRLTEKEA KETAKKLYSLTKGVKSHSESLKLSKFWRSGSESLIFNRLEEMADQETPRTPVLGATITEALQRKNLKKSSFLTSRINWTI QSSGVDYLHLLITSMHYLIKKYGISARLFVTVHDEIRYMVKEEDAYRVALALQISNIWTRAMFCHQVGINDLPLSCAFFS SVDIDHVLRKEVDLDCVTLSHPNPIKPGSSIDIFNTLKVCSTLDKPNSSKFTQDNDLGFQFDFDKVEYQPITPVILELDS KKGSLVPSIAAQISTSTKELRAVEYITDHCESDWSSFFTDEKKTLFINGKSKTVRKSTKDNLKTVSKQKRVTKTGSITPV FGTLEKKKKKLQLTYHNKIKKKMYQIPLMFLMTMRYPIY
GO term prediction
Biological Process
GO:0006260 DNA replication
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Cellular Component
GO:0005760 gamma DNA polymerase complex