Protein
MIA_04908_1
Length
1,500 amino acids
Browser: contig07:139203-143753+
Protein function
| EGGNOG: | 0PFP7 | ROM2 | nucleotide exchange factor |
|---|---|---|---|
| SGD closest match: | S000004363 | ROM2 | RHO1 GDP-GTP exchange protein 2 |
| CGD closest match: | CAL0000177920 | ROM2 | Rho family guanine nucleotide exchange factor |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MCA_01188_1 | 69.365% | 976 | 0.0 | MCA_01188_1 |
| A0A060T202_BLAAD | 58.453% | 1112 | 0.0 | ARAD1C21076p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C21076g PE=4 SV=1 |
| A0A0J9X8W4_GEOCN | 70.771% | 804 | 0.0 | Similar to Saccharomyces cerevisiae YGR070W ROM1 GDP/GTP exchange protein (GEP) for Rho1p and Rho2p OS=Geotrichum candidum GN=BN980_GECA05s04443g PE=4 SV=1 |
| A0A167DC69_9ASCO | 60.232% | 1036 | 0.0 | Rho family guanine nucleotide exchange factor ROM2 OS=Sugiyamaella lignohabitans GN=ROM2 PE=4 SV=1 |
| UniRef50_A0A167DC69 | 60.232% | 1036 | 0.0 | Rho family guanine nucleotide exchange factor ROM2 n=4 Tax=Saccharomycetales TaxID=4892 RepID=A0A167DC69_9ASCO |
| A0A1E3PKG6_9ASCO | 64.141% | 792 | 0.0 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_60047 PE=4 SV=1 |
| A0A1E4TEF9_9ASCO | 58.177% | 801 | 0.0 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26059 PE=4 SV=1 |
| Q6CDY6_YARLI | 55.860% | 802 | 0.0 | YALI0B20218p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B20218g PE=4 SV=1 |
| Q5AH90_CANAL | 39.841% | 1009 | 0.0 | Rho family guanine nucleotide exchange factor OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ROM2 PE=4 SV=1 |
| ROM2_YEAST | 37.984% | 1032 | 0.0 | RHO1 GDP-GTP exchange protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ROM2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2005
Predicted cleavage: 114
Protein family membership
None predicted.
Domains and repeats
-
Domain
-
Domain
1
200
400
600
800
1000
1200
1400
1500
Detailed signature matches
no IPR
Unintegrated signatures
-
-
PF15405 (PH_5)
-
cd00160 (RhoGEF)
-
cd04435 (DEP_fRom2)
-
mobidb-lite (disord...)
Residue annotation
-
GTPase interaction...
Protein sequence
>MIA_04908_1 MDGNRHFNNNSSHKQPRPSQSIPQLATQFQATSLHPTSSFNTAHQGNFHQGPSPQQHQQQQQQPQQFYNSSAAAAAASSA TLAPIPLSTSPQRPLGLSTRDAAFTNIFGFARPQPSVSGPVSTNTATEPGSERHFSASNTTFGYPQAGTFPDHQVASNIT GNGFGSGGGVGAPLSFQGPINSTQMAPVPVTTKFNSAYDEGINPRLYANGANYNASSTGLARPNRSESPAPSPFSVAPGQ QPTFYTPPPLAQVPPRPGSAGPQLQPAFQQKDINRNFDFVSANQPHHHQQKQPQQFAHGEGPQPHRPSLQAPTRQFNSLP RSPSLPANHLSAQLYQTQQPSPPPQQPQQLRSASGGSLPHHVPVPHTVRPPANQYNPNVIPVLPAPSTRSMSLTSASRPP GAADFNGRSHTMTLSGRIIPRRQGIEMLPHLHSTGGSGGNNTNQRSTSTGSASSSSASLVAMKVSKSKNQRSTSTSSHAS DDGTSVSEAGQAFGASHGSPNSSFSRGGAPFAGPTTIITTSRRSPLVKSAFLSKVAKAFQQRIVLRDRVKNELTYTKAFT GVEAVDLICYIIQTTDRNMALLLGRALDAQKFFHDVTYEHRLRDRANEVYQFNEIMVEREEDDHSHMSNSLSNSTTSISS MNSITATAGGAVVPYTGNKGALASSHAANERASSVGSVSQQLVPATPEHLHHGRSENGKKSEATSVPVNGIFVILTDCYS PTCTPDRLCYSIGCPRRLEQQARLNMKPNSVLKRAESRLSLHGDDEKEHKLWIHTVPKDIVDSVSDREKKRQEVICELIY TERDFVKDLEYLRDFWIKPLRASNIIPESRREEFLKQVFGVIPEVHSVNIRLAEALTKRQQQSPIVYQVGDIFLEYVPKF EPFIKYGKEQVYAKYEFEREKSINPQFAKFVDETERMKESRKLELNGYLTKPTTRLARYPLLLDAILKVTEDSNPDKENL PKARTLVREFLTQVNIESGRSENRQQLKQLDDRIRFRPNEWVDLKLKKADRQIIFKGTMKKRTGDKENQGDVLVYLFDNS LLFLRPKISNKREILNVYRKPIPLELLVINESDEAPSKGTTRRTSSSLISTAAKVAPMKENAQNRYPIMFQHLGRRGYEL ILYTSSYISRKKWVENIMHQKKVLMEKSNVYTQHILMQRFFDSTNRVICVTPFDGGRKLLYGTDNGIWISDTKMSADGAG RVTTKPTRVINMSSVSQIDVIEEYNMLLAMSEKTLYTWPLECLEMFDPVSNERRARKVIGHINFYKVGLGKGKILVCTAK NGSSTSTLKVLEPADPTPRGKRPPLRKFLRPQTEGLGVLKEMVVSSEIVSINFLTNNLCVGCTKGFEIMSLDTYMSESVL ALADTALDFVTRRETVKPIAIYRLQSEFLLNYSDFSFYVNASGWLSRSKWIIHWEGLPQGFAMSYPYIIAFEPNFVEIRH MESGEIVRVITGENIRFLHENTREIMYAFEDENGYDVVASLDFWQMEKKQGSGGAKKEGE
GO term prediction
Biological Process
GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction
Molecular Function
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Cellular Component
None predicted.