Protein

MIA_04868_1

Length
530 amino acids


Browser: contig07:44373-45966+

Protein function

EGGNOG:0PHZ0FG05525.1Ceramide synthase
SGD closest match:S000000995LAG1Sphingosine N-acyltransferase LAG1
CGD closest match:CAL0000185837LAG1Sphingosine N-acyltransferase

Protein alignments

%idAln lengthE-value
MCA_05300_154.021%4851.50e-169MCA_05300_1
A0A0J9X9L5_GEOCN50.000%4541.10e-148Similar to Saccharomyces cerevisiae YKL008C LAC1 Ceramide synthase component OS=Geotrichum candidum GN=BN980_GECA06s01231g PE=4 SV=1
A0A167DPT5_9ASCO58.989%3567.01e-145Sphingosine N-acyltransferase LAG1 OS=Sugiyamaella lignohabitans GN=LAG1 PE=4 SV=1
A0A060T2S4_BLAAD59.184%3439.49e-144ARAD1C35134p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35134g PE=4 SV=1
Q6C2N3_YARLI54.000%3501.18e-132YALI0F06424p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F06424g PE=4 SV=1
UniRef50_Q6C2N354.000%3502.74e-129YALI0F06424p n=11 Tax=Ascomycota TaxID=4890 RepID=Q6C2N3_YARLI
Q5A879_CANAL59.561%3194.58e-127Sphingosine N-acyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=LAG1 PE=4 SV=1
A0A1E3PGJ2_9ASCO57.846%3253.10e-122Longevity assurance proteins LAG1/LAC1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52136 PE=4 SV=1
LAG1_YEAST51.902%3683.81e-120Sphingosine N-acyltransferase LAG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LAG1 PE=1 SV=1
A0A1E4TBG7_9ASCO55.128%3129.88e-111Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3737 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0195

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 500 530

Detailed signature matches

    1. PIRSF005225 (LAG1_LAC1)
    1. PF08390 (TRAM1)
    1. PS50922 (TLC)
    2. PF03798 (TRAM_LAG1_...)
    3. SM00724 (lag1_27)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)
  2. mobidb-lite (disord...)

Protein sequence

>MIA_04868_1
MSSANANDDDIIDFPKIQKLDSPAHPRRKSSVGNIDLGDTTVPALSTMPLDPRLERESRHRLRVLSASSANMPVVVEASS
ASEPSSSSQSAAEDDDDNIDSGTADTEVSSSSLQSSKPGLGARKRKPQKSPAATTSGHHPRLTTISPASPALQIWYRIRE
LAYRNTWLTPLVILALMASAYLVHPSPSNPLHMFLRLSYQRFDADGSPLDLYGKGYRDFAFVATGIVFFMFFREFCMQVI
LQPLAVNVFGLHRRSKISRFLEQTYAIVYFSISASFGFYIMYHNKDGLWYYNTRAFYEHYPHKAHDGLFKAFYLLQAAFW
AQQSIILMLQVEKPRKDFRELVFHHVVTIALIFCSYRFHFAMMGIAVFITMDTSDIFLSLSKTLNYLDSKYTPAMFVLFI
AVWVYLRHYLNIVILWSVLTQFRTVGPYQLSFPDQQYKCWISQIITFFLILALQLVNLYWLFLIFRILYRYVVGGVQKDE
RSDDEDEEEELQDDLQDKNDELLQAEDQEKRQRILEAVAISKQAKQVKSE

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane