Protein

MIA_04864_1

Length
573 amino acids


Browser: contig07:29699-31421-

Protein function

EGGNOG:0PIAFMDM34Component of the ERMES MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10 (By similarity)
SGD closest match:S000003187MDM34Mitochondrial distribution and morphology protein 34
CGD closest match:CAL0000184363MDM34Mitochondrial distribution and morphology protein 34

Protein alignments

%idAln lengthE-value
MCA_03722_164.737%3805.86e-162MCA_03722_1
A0A0J9XHG0_GEOCN59.229%3633.92e-137Mitochondrial distribution and morphology protein 34 OS=Geotrichum candidum GN=MDM34 PE=3 SV=1
UniRef50_A0A0J9XHG059.229%3638.02e-134Mitochondrial distribution and morphology protein 34 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHG0_GEOCN
A0A167EVQ3_9ASCO53.297%3641.26e-121Mitochondrial distribution and morphology protein 34 OS=Sugiyamaella lignohabitans GN=MDM34 PE=3 SV=1
A0A1E3PR98_9ASCO52.732%3661.34e-117Mitochondrial distribution and morphology protein 34 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=MDM34 PE=3 SV=1
MDM34_YARLI51.923%3649.22e-112Mitochondrial distribution and morphology protein 34 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=MDM34 PE=3 SV=1
A0A060T8C2_BLAAD55.195%3081.49e-105Mitochondrial distribution and morphology protein 34 OS=Blastobotrys adeninivorans GN=MDM34 PE=3 SV=1
A0A1E4TDK4_9ASCO55.385%1951.58e-73Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_13309 PE=4 SV=1
MDM34_CANAL50.667%2255.56e-61Mitochondrial distribution and morphology protein 34 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDM34 PE=3 SV=2
MDM34_YEAST30.131%2291.92e-15Mitochondrial distribution and morphology protein 34 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MDM34 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0335

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MIA_04864_1
MSFKFNWDSFTSDDDFYDRVRTLLSDALNRGKMPNILADRIRVRELYLGDESPQLEILEVGDLADDRFRGIFKLTYAGNA
SITLTTKIRANPVQVYAMSAPSFCMPRFQNSAAASLSIPLNLTLSDIKLSGIIILVFSKAKGLTLVFRNDPLQSIRVTST
FDTLPGIARFLQTQIETQIRLLFREDLPAILHKLSHKWTPQSNIGLEKSRLHQKMAEHQREKQAAAAAGGTDPTTSVAYN
EDFDVDAAAEHHDEDIQEEYVQFGDINPDMPILSPASMVKLNALCASQLTLSLFTPSIKETVYRANLEAHGEGATGSAGS
SGSALSALQHVDGSVDLDEIMKIQSRNYFRTSHAKPRRRVIKMGGAKTKAPQPPSGASASPAPITPPAKTIPAAAPVAEK
TTFAVSTSTSALTRTKTTTPLRKSARTTSRALKKPDAGLQAIPQSPSDGSEVAGMSPLGMRVSTPETPVKSSKPFTTSSM
PKPTDPEKAQVYARVQHSMRSQPPVLRVVVDAPLNKAPASAANSNAQLVLPKRRPRSGANHHGSSVGRKSAKSDEALEDE
GREYGSPPPAYVA

GO term prediction

Biological Process

GO:0007005 mitochondrion organization

Molecular Function

None predicted.

Cellular Component

GO:0032865 ERMES complex