Protein

MIA_04833_1

Length
504 amino acids


Browser: contig06:1094715-1096230-

Protein function

EGGNOG:0PHC0PGUG_00888resistance protein
SGD closest match:S000001090YHK8Probable drug/proton antiporter YHK8
CGD closest match:CAL0000189339orf19.3395Uncharacterized protein

Protein alignments

%idAln lengthE-value
MCA_05037_161.915%4700.0MCA_05037_1
A0A0J9XCN8_GEOCN53.862%4929.18e-163Similar to Saccharomyces cerevisiae YHR048W YHK8 Presumed antiporter of the DHA1 family of multidrug resistance transporters OS=Geotrichum candidum GN=BN980_GECA08s01968g PE=4 SV=1
UniRef50_A0A0J9XBE554.158%4691.67e-142Similar to Saccharomyces cerevisiae YHR048W YHK8 Presumed antiporter of the DHA1 family of multidrug resistance transporters n=3 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBE5_GEOCN
Q5A4P7_CANAL40.278%5042.09e-112Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3395 PE=4 SV=1
YHK8_YEAST38.367%4908.46e-108Probable drug/proton antiporter YHK8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHK8 PE=1 SV=1
A0A060TG04_BLAAD37.550%4981.53e-99ARAD1D27214p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27214g PE=4 SV=1
A0A167BZ56_9ASCO39.375%4801.12e-95Yhk8p OS=Sugiyamaella lignohabitans GN=YHK8 PE=4 SV=1
A0A1E4TE36_9ASCO39.149%4707.44e-95Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_99540 PE=4 SV=1
A0A1E3PJD3_9ASCO34.647%4822.70e-76Polyamine transport protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24585 PE=4 SV=1
Q6C1S6_YARLI34.756%4921.44e-74YALI0F13739p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13739g PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2601

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 450 504

Detailed signature matches

    1. PF07690 (MFS_1)
    1. PS50850 (MFS)
    2. SSF103473 (MFS gene...)
    3. cd06174 (MFS)
    1. PS00216 (SUGAR_TRAN...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)

Residue annotation

  1. putative substrate...

Protein sequence

>MIA_04833_1
MLVEKTAECGDIKTSTKIKWESTPPKTEDDGDFCIAWDGFDDKENVKNRPLLLRYIYAFLILLAAVAVTTSSSIYALSID
HLHNEFHQGHTVNALGITLFLFGMGVGPMFLSPISEQFGRKKPYIFSLIFMICFSLGGGFGKNIETILICRFLGGFSGSC
FMGVSAGSVSDLFNHDEISLPLFLYTLTPFLGAGMGPLISGFINQYISGPNSWRWTFHVMTIYSGFILFFIVFIVPETYP
PILLRMKAKRIRKEKDDDRYYAPIEHSDIKFSVKTVMMSVKRPTLMLVKIPMLLMLCIYCGLLLSLLYGFFVSYPYVFKT
VYLFTPSQIGLAFIGIIIGCALCLPFSFLNDTIVKSLTKRANGTSEPEFQLVQTIIGSIVTPIGLFVFGWSSKPSLHWIG
PIFGGGIVMWGSMVAMNGIFSYTIRSWHPFSASAMACNGVVRSTIAAVFPLFSLQMYQNLGIQWASTLLALLCVIYIPMP
IGLFFYGKKIRSKSTFDMDDVFII

GO term prediction

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0005215 transporter activity

Cellular Component

GO:0016021 integral component of membrane