Protein
MCA_05037_1
Length
489 amino acids
Browser: contigD:196017-197487-
RNA-seq: read pairs 698, FPKM 17.6, percentile rank 37.9% (100% = highest expression)
Protein function
| EGGNOG: | 0PHC0 | PGUG_00888 | resistance protein |
|---|---|---|---|
| SGD closest match: | S000001090 | YHK8 | Probable drug/proton antiporter YHK8 |
| CGD closest match: | CAL0000189339 | orf19.3395 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04833_1 | 61.91% | 470 | 0.0 | MIA_04833_1 |
| A0A0J9XCN8_GEOCN | 59.36% | 497 | 1e-168 | Similar to Saccharomyces cerevisiae YHR048W YHK8 Presumed antiporter of the DHA1 family of multidrug resistance transporters OS=Geotrichum candidum GN=BN980_GECA08s01968g PE=4 SV=1 |
| UniRef50_A0A0J9XBE5 | 57.14% | 497 | 1e-150 | Similar to Saccharomyces cerevisiae YHR048W YHK8 Presumed antiporter of the DHA1 family of multidrug resistance transporters n=3 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XBE5_GEOCN |
| Q5A4P7_CANAL | 45.37% | 518 | 3e-125 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.3395 PE=4 SV=1 |
| YHK8_YEAST | 43.15% | 482 | 2e-115 | Probable drug/proton antiporter YHK8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHK8 PE=1 SV=1 |
| A0A167BZ56_9ASCO | 43.69% | 499 | 4e-114 | Yhk8p OS=Sugiyamaella lignohabitans GN=YHK8 PE=4 SV=1 |
| A0A060TG04_BLAAD | 39.59% | 485 | 3e-102 | ARAD1D27214p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D27214g PE=4 SV=1 |
| A0A1E4TE36_9ASCO | 41.21% | 478 | 2e-93 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_99540 PE=4 SV=1 |
| Q6C1S6_YARLI | 37.43% | 505 | 1e-78 | YALI0F13739p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13739g PE=4 SV=1 |
| A0A1E3PF73_9ASCO | 37.38% | 428 | 2e-72 | MFS general substrate transporter OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84082 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0093
Protein family membership
- Major facilitator superfamily (IPR011701)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
400
450
489
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
Residue annotation
-
putative substrate...
Protein sequence
>MCA_05037_1 MDIEPEELKDTIVSDNTVDSEIEVKWDGIDDRENAKLLPKALRYVYALIISTSSLCVTSYSSIYSMAVDGIIKDFGHISH TVATLGITLFLLAMGFGPMFLSPISENFGRRIPYIGALLGMVAFSFGTAFANNIATLLVCRFFCGFSGSCFMGVAAGSFA DLFDKHEIAIPVMLYTLTPFLGAGLGPLVGGFINQYIDGNGNWRWTFHVMTIYAAVMLVLIVLVVPETYPPILLRKKAIR LRKQTGDSRYYAPIERSKQSLFSAIFLSCERPIKMLIFEPMLTLLCIYTGLLLALLYSFFVSYPYVFRTVYHFSISQVGM AFIGIIVGCSLAGPIALLNKKVVKWQVDRNNGVYQPEFELPQTMLGSVIVPIGLFLFGWLARPSIHWIGPVIGGGTVLFG NVVATNGIFAYTIDVWRQYSASAMACNGVVRSSIAAVFPLFSLQMYEKLGINWASTLLALLCVMYIPMPILFYKYGKKIR SKSKYSVHI
GO term prediction
Biological Process
GO:0055085 transmembrane transport
Molecular Function
GO:0005215 transporter activity
Cellular Component
GO:0016021 integral component of membrane